dc.creator | Zvicer, Jovana | |
dc.creator | Samardžić, M. | |
dc.creator | Mišković-Stanković, Vesna | |
dc.creator | Obradović, Bojana | |
dc.date.accessioned | 2021-03-10T12:38:01Z | |
dc.date.available | 2021-03-10T12:38:01Z | |
dc.date.issued | 2015 | |
dc.identifier.isbn | 978-146737983-0 | |
dc.identifier.uri | http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2880 | |
dc.description.abstract | Alginate nanocomposite hydrogels with incorporated electrochemically synthesized silver nanoparticles were investigated regarding cytotoxicity in vitro. Direct contact test of Ag/alginate discs was applied in 2D monolayer cultures of bovine calf chondrocytes while a 3D culture of bovine articular cartilage explants pressed by the discs was established in a biomimetic bioreactor with dynamic compression in the physiological regime (10 % strain, 0.84 Hz frequency, 1 h on / 1 h off). Moderate cytotoxicity was observed in 2D cell cultures as opposed to findings in 3D explant cultures, which were not affected by the Ag/alginate discs despite the compression. | en |
dc.publisher | 15th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2015 | |
dc.rights | restrictedAccess | |
dc.source | 2015 IEEE 15th International Conference on Bioinformatics and Bioengineering, BIBE 2015 | |
dc.title | Cytotoxicity studies of Ag/alginate nanocomposite hydrogels in 2D and 3D cultures | en |
dc.type | conferenceObject | |
dc.rights.license | ARR | |
dc.identifier.doi | 10.1109/BIBE.2015.7367664 | |
dc.identifier.pmid | | |
dc.identifier.scopus | 2-s2.0-84962875856 | |
dc.type.version | publishedVersion | |