dc.creator | Kostić, Danijela | |
dc.creator | Vidović, Srđan | |
dc.creator | Obradović, Bojana | |
dc.date.accessioned | 2021-03-10T13:15:35Z | |
dc.date.available | 2021-03-10T13:15:35Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1388-0764 | |
dc.identifier.uri | http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3458 | |
dc.description.abstract | A stepwise experimental and mathematical modeling approach was used to assess silver release from nanocomposite Ag/alginate microbeads in wet and dried forms into water and into normal saline solution chosen as a simplified model for certain biological fluids (e.g., blood plasma, wound exudates, sweat, etc). Three phenomena were connected and mathematically described: diffusion of silver nanoparticles (AgNPs) within the alginate hydrogel, AgNP oxidation/dissolution and reaction with chloride ions, and diffusion of the resultant silver-chloride species. Mathematical modeling results agreed well with the experimental data with the AgNP diffusion coefficient estimated as 1.3 x 10(-18) m(2) s(-1), while the first-order kinetic rate constant of AgNP oxidation/dissolution and diffusivity of silver-chloride species were shown to be inversely related. In specific, rapid rehydration and swelling of dry Ag/alginate microbeads induced fast AgNP oxidation/dissolution reaction with Cl- and AgCl precipitation within the microbeads with the lowest diffusivity of silver-chloride species compared to wet microbeads in normal saline. The proposed mathematical model provided an insight into the phenomena related to silver release from nanocomposite Ca-alginate hydrogels relevant for use of antimicrobial devices and established, at the same time, a basis for further in-depth studies of AgNP interactions in hydrogels in the presence of chloride ions. | en |
dc.publisher | Springer, Dordrecht | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46010/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/45019/RS// | |
dc.rights | restrictedAccess | |
dc.source | Journal of Nanoparticle Research | |
dc.subject | Modeling and simulation | en |
dc.subject | Environmental effects | en |
dc.subject | Diffusion | en |
dc.subject | Silver nanoparticles | en |
dc.subject | Silver-chloride species | en |
dc.subject | Alginate hydrogel | en |
dc.title | Silver release from nanocomposite Ag/alginate hydrogels in the presence of chloride ions: experimental results and mathematical modeling | en |
dc.type | article | |
dc.rights.license | ARR | |
dc.citation.issue | 3 | |
dc.citation.other | 18(3): - | |
dc.citation.rank | M22 | |
dc.citation.volume | 18 | |
dc.identifier.doi | 10.1007/s11051-016-3384-3 | |
dc.identifier.scopus | 2-s2.0-84961151231 | |
dc.identifier.wos | 000372283600003 | |
dc.type.version | publishedVersion | |