TY  - CONF
AU  - Matić, Tamara
AU  - Ležaja Zebić, Maja
AU  - Miletić, Vesna
AU  - Janaćković, Đorđe
AU  - Veljović, Đorđe
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6685
UR  - https://ecers2023.org/en/program/full-conference-program/34
AB  - The main drawback of resin-based composites (RBCs) widely used in restorative dentistry presents their volumetric shrinkage during the polymerization that can lead to clinical failures of restorations such asmarginal gap formation, bacterial microleakage, fractures, and postoperative sensitivity. To address this problem, sintered hydroxyapatite based dental inserts were introduced in the central part of molar teethrestoration, due to chemical and structural similarities with inorganic part of teeth.
The fabrication of bioceramic dental inserts based on HAP doped with Sr and/or Mg ions presents a way to obtain a dentin substitute that has even greater resemblance to the biological apatite in dentin. However, ion-substitutions arise lattice strain that can have a signifi cant impact on phase composition and properties of apatite materials, especially upon thermal treatment, which could be determining for their further application.
The aims of this study were to comparatively analyze physico-chemical and mechanical properties of the Sr- or Mg-, and Sr+Mg substituted HAP based dental inserts; and evaluate their possible application as dentinsubstitutes. Mono (5 mol. % Sr or Mg ions) and binary- (3 mol.% Sr and 3 mol.% Mg ions) doped HAP nanoparticles were hydrothermally obtained, isostatically pressed into compacts and eventually sintered at 1200°C to obtain dental inserts. The inserts are meant to be adhered to the cavity walls as well as topped with resin composite for sealing and esthetic purposes. Bonding ability of obtained inserts with different commercialrestorative materials, as well as fracture resistance of human molars restored with doped HAP inserts was investigated.
Ion doping was found to infl uence phase compositions of sintered inserts, leading to different mechanical properties and etching behavior of inserts. All inserts showed fracture toughness and bonding ability torestorative materials similar to dentin, while the highest bond strength was obtained for HAP insert doped with 5 mol% Mg (Mg-HAP) bonded to. Fracture resistance of human molars restored with Mg-HAP wasshown to be similar to the fracture resistance of the conventionally restored molars. In conclusion the obtained hydroxyapatite based dental inserts present promising materials for application as dentin substitutes inrestorative dentistry, which have the potential to extend the durability of the restoration.
PB  - European Ceramic Society
C3  - The XVIIIth Conference and Exhibition of the European Ceramic Society (ECerS), Lyon-France, 2-6 July 2023
T1  - Sintered dental inserts based on ion-doped hydroxyapatite as dentin substitutes
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6685
ER  - 

@conference{
author = "Matić, Tamara and Ležaja Zebić, Maja and Miletić, Vesna and Janaćković, Đorđe and Veljović, Đorđe",
year = "2023",
abstract = "The main drawback of resin-based composites (RBCs) widely used in restorative dentistry presents their volumetric shrinkage during the polymerization that can lead to clinical failures of restorations such asmarginal gap formation, bacterial microleakage, fractures, and postoperative sensitivity. To address this problem, sintered hydroxyapatite based dental inserts were introduced in the central part of molar teethrestoration, due to chemical and structural similarities with inorganic part of teeth.
The fabrication of bioceramic dental inserts based on HAP doped with Sr and/or Mg ions presents a way to obtain a dentin substitute that has even greater resemblance to the biological apatite in dentin. However, ion-substitutions arise lattice strain that can have a signifi cant impact on phase composition and properties of apatite materials, especially upon thermal treatment, which could be determining for their further application.
The aims of this study were to comparatively analyze physico-chemical and mechanical properties of the Sr- or Mg-, and Sr+Mg substituted HAP based dental inserts; and evaluate their possible application as dentinsubstitutes. Mono (5 mol. % Sr or Mg ions) and binary- (3 mol.% Sr and 3 mol.% Mg ions) doped HAP nanoparticles were hydrothermally obtained, isostatically pressed into compacts and eventually sintered at 1200°C to obtain dental inserts. The inserts are meant to be adhered to the cavity walls as well as topped with resin composite for sealing and esthetic purposes. Bonding ability of obtained inserts with different commercialrestorative materials, as well as fracture resistance of human molars restored with doped HAP inserts was investigated.
Ion doping was found to infl uence phase compositions of sintered inserts, leading to different mechanical properties and etching behavior of inserts. All inserts showed fracture toughness and bonding ability torestorative materials similar to dentin, while the highest bond strength was obtained for HAP insert doped with 5 mol% Mg (Mg-HAP) bonded to. Fracture resistance of human molars restored with Mg-HAP wasshown to be similar to the fracture resistance of the conventionally restored molars. In conclusion the obtained hydroxyapatite based dental inserts present promising materials for application as dentin substitutes inrestorative dentistry, which have the potential to extend the durability of the restoration.",
publisher = "European Ceramic Society",
journal = "The XVIIIth Conference and Exhibition of the European Ceramic Society (ECerS), Lyon-France, 2-6 July 2023",
title = "Sintered dental inserts based on ion-doped hydroxyapatite as dentin substitutes",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6685"
}

Matić, T., Ležaja Zebić, M., Miletić, V., Janaćković, Đ.,& Veljović, Đ.. (2023). Sintered dental inserts based on ion-doped hydroxyapatite as dentin substitutes. in The XVIIIth Conference and Exhibition of the European Ceramic Society (ECerS), Lyon-France, 2-6 July 2023
European Ceramic Society..
https://hdl.handle.net/21.15107/rcub_technorep_6685

Matić T, Ležaja Zebić M, Miletić V, Janaćković Đ, Veljović Đ. Sintered dental inserts based on ion-doped hydroxyapatite as dentin substitutes. in The XVIIIth Conference and Exhibition of the European Ceramic Society (ECerS), Lyon-France, 2-6 July 2023. 2023;.
https://hdl.handle.net/21.15107/rcub_technorep_6685 .

Matić, Tamara, Ležaja Zebić, Maja, Miletić, Vesna, Janaćković, Đorđe, Veljović, Đorđe, "Sintered dental inserts based on ion-doped hydroxyapatite as dentin substitutes" in The XVIIIth Conference and Exhibition of the European Ceramic Society (ECerS), Lyon-France, 2-6 July 2023 (2023),
https://hdl.handle.net/21.15107/rcub_technorep_6685 .

TY  - JOUR
AU  - Matić, Tamara
AU  - Ležaja Zebić, Maja
AU  - Miletić, Vesna
AU  - Trajković, Isaak
AU  - Milošević, Miloš
AU  - Racić, Aleksandar
AU  - Veljović, Đorđe
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6659
AB  - This study aimed to (1) comparatively analyze properties of Sr- and Mg-substituted
hydroxyapatite (HAP)-based dental inserts; (2) evaluate insert bonding to restorative
materials, and (3) evaluate the effect of doped HAP inserts on fracture resistance
(FR) of human molars with large occlusal restorations. By ion-doping with Sr or Mg,
3 insert types were obtained and characterized using XRD, SEM, Vickers hardness and
fracture toughness. Shear bond strength (SBS) was determined between acid etched or
unetched inserts and following materials: Maxcem cement (Kerr); Filtek Z250
(3M) bonded with Single Bond Universal (SBU; 3M) or Clearfil Universal (Cf; Kuraray).
Modified Class I cavities were prepared in 16 intact molars and restored using insert
+ composite or composite only (control) (n = 8/group). FR of restored molars was
determined by static load until fracture upon thermal cycling. Fracture toughness was
similar between Sr/Mg-doped inserts (0.94–1.04 MPam 1/2 p = .429). Mg-doped
inserts showed greater hardness (range 4.78–5.15 GPa) than Sr6 inserts (3.74
± 0.31 GPa; p < .05). SBS for SBU and Cf adhesives (range 7.19–15.93 MPa) was higher
than for Maxcem (range 3.07–5.95 MPa) (p < .05). There was no significant difference
in FR between molars restored with insert-containing and control restorations (3.00
± 0.30 kN and 3.22 ± 0.42 kN, respectively; p > .05). HAP-based inserts doped with
Mg/Sr had different composition and mechanical properties. Adhesive bonding to
inserts resulted in greater bond strength than cementation, which may be improved by
insert acid-etching. Ion-doped HAP inserts did not affect FR of restored molars. In conclusion,
HAP-based dental inserts may potentially replace dentin in large cavities, without
affecting fracture resistance of restored teeth.
PB  - Wiley Periodicals LLC.
T2  - Journal of Biomedical Materials Research Part B: Applied Biomaterials
T1  - Hydroxyapatite-based dental inserts: microstructure, mechanical properties, bonding efficiency and fracture resistance of molars with occlusal restorations
DO  - 10.1002/jbm.b.35331
ER  - 

@article{
author = "Matić, Tamara and Ležaja Zebić, Maja and Miletić, Vesna and Trajković, Isaak and Milošević, Miloš and Racić, Aleksandar and Veljović, Đorđe",
year = "2023",
abstract = "This study aimed to (1) comparatively analyze properties of Sr- and Mg-substituted
hydroxyapatite (HAP)-based dental inserts; (2) evaluate insert bonding to restorative
materials, and (3) evaluate the effect of doped HAP inserts on fracture resistance
(FR) of human molars with large occlusal restorations. By ion-doping with Sr or Mg,
3 insert types were obtained and characterized using XRD, SEM, Vickers hardness and
fracture toughness. Shear bond strength (SBS) was determined between acid etched or
unetched inserts and following materials: Maxcem cement (Kerr); Filtek Z250
(3M) bonded with Single Bond Universal (SBU; 3M) or Clearfil Universal (Cf; Kuraray).
Modified Class I cavities were prepared in 16 intact molars and restored using insert
+ composite or composite only (control) (n = 8/group). FR of restored molars was
determined by static load until fracture upon thermal cycling. Fracture toughness was
similar between Sr/Mg-doped inserts (0.94–1.04 MPam 1/2 p = .429). Mg-doped
inserts showed greater hardness (range 4.78–5.15 GPa) than Sr6 inserts (3.74
± 0.31 GPa; p < .05). SBS for SBU and Cf adhesives (range 7.19–15.93 MPa) was higher
than for Maxcem (range 3.07–5.95 MPa) (p < .05). There was no significant difference
in FR between molars restored with insert-containing and control restorations (3.00
± 0.30 kN and 3.22 ± 0.42 kN, respectively; p > .05). HAP-based inserts doped with
Mg/Sr had different composition and mechanical properties. Adhesive bonding to
inserts resulted in greater bond strength than cementation, which may be improved by
insert acid-etching. Ion-doped HAP inserts did not affect FR of restored molars. In conclusion,
HAP-based dental inserts may potentially replace dentin in large cavities, without
affecting fracture resistance of restored teeth.",
publisher = "Wiley Periodicals LLC.",
journal = "Journal of Biomedical Materials Research Part B: Applied Biomaterials",
title = "Hydroxyapatite-based dental inserts: microstructure, mechanical properties, bonding efficiency and fracture resistance of molars with occlusal restorations",
doi = "10.1002/jbm.b.35331"
}

Matić, T., Ležaja Zebić, M., Miletić, V., Trajković, I., Milošević, M., Racić, A.,& Veljović, Đ.. (2023). Hydroxyapatite-based dental inserts: microstructure, mechanical properties, bonding efficiency and fracture resistance of molars with occlusal restorations. in Journal of Biomedical Materials Research Part B: Applied Biomaterials
Wiley Periodicals LLC...
https://doi.org/10.1002/jbm.b.35331

Matić T, Ležaja Zebić M, Miletić V, Trajković I, Milošević M, Racić A, Veljović Đ. Hydroxyapatite-based dental inserts: microstructure, mechanical properties, bonding efficiency and fracture resistance of molars with occlusal restorations. in Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2023;.
doi:10.1002/jbm.b.35331 .

Matić, Tamara, Ležaja Zebić, Maja, Miletić, Vesna, Trajković, Isaak, Milošević, Miloš, Racić, Aleksandar, Veljović, Đorđe, "Hydroxyapatite-based dental inserts: microstructure, mechanical properties, bonding efficiency and fracture resistance of molars with occlusal restorations" in Journal of Biomedical Materials Research Part B: Applied Biomaterials (2023),
https://doi.org/10.1002/jbm.b.35331 . .

TY  - JOUR
AU  - Matić, Tamara
AU  - Zebić, M. Ležaja
AU  - Miletić, Vesna
AU  - Cvijović-Alagić, Ivana
AU  - Petrović, Rada
AU  - Janaćković, Đorđe
AU  - Veljović, Đorđe
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5362
AB  - The aim of this study was to investigate the influence of binary Sr, Mg ion-doping compared to the single-ion doping effects on the phase composition and morphology of hydrothermally obtained calcium hydroxyapatite (HAP) powders and on the phase composition, microstructure, and mechanical properties of the sintered materials. Additionally, the focus of this study was to investigate the possible utilization of the binary doped Sr,Mg-HAP compacts as dentin substitutes in restorative dentistry by evaluating their bonding ability with commercially available restorative materials using the shear bond strength test (SBS). The hydrothermally obtained mono-doped Mg5 and Sr5 showed the monophasic apatite structure, while in all co-doped samples β-TCP phase was formed, resulting in biphasic calcium phosphate (BCP) powders. It was confirmed that co-doping with Sr and Mg ions led to the thermal stabilization of the β-TCP phase by suppressing the phase transition into α-TCP when sintered at 1200 °C. Moreover, the co-presence of Mg ions significantly improved the hardness of Sr-doped HAP from 3.74 to 5.02 GPa. Sr,Mg-HAP dental inserts were found to achieve sufficient bonding (13.53 MPa) through the micromechanical interlocking with Z250 dental composite and Single Bond Universal dental adhesive applied with a total etch approach. The SBS values obtained for the SrMg-HAP insert were similar to the literature data on bonding ability with human dentin, indicating that binary doped Sr,Mg-HAP ceramics present a promising material for application in restorative dentistry as dentin substitutes.
T2  - Ceramics International
T1  - Sr,Mg co-doping of calcium hydroxyapatite: Hydrothermal synthesis, processing, characterization and possible application as dentin substitutes
EP  - 11165
IS  - 8
SP  - 11155
VL  - 48
DO  - 10.1016/j.ceramint.2021.12.335
ER  - 

@article{
author = "Matić, Tamara and Zebić, M. Ležaja and Miletić, Vesna and Cvijović-Alagić, Ivana and Petrović, Rada and Janaćković, Đorđe and Veljović, Đorđe",
year = "2022",
abstract = "The aim of this study was to investigate the influence of binary Sr, Mg ion-doping compared to the single-ion doping effects on the phase composition and morphology of hydrothermally obtained calcium hydroxyapatite (HAP) powders and on the phase composition, microstructure, and mechanical properties of the sintered materials. Additionally, the focus of this study was to investigate the possible utilization of the binary doped Sr,Mg-HAP compacts as dentin substitutes in restorative dentistry by evaluating their bonding ability with commercially available restorative materials using the shear bond strength test (SBS). The hydrothermally obtained mono-doped Mg5 and Sr5 showed the monophasic apatite structure, while in all co-doped samples β-TCP phase was formed, resulting in biphasic calcium phosphate (BCP) powders. It was confirmed that co-doping with Sr and Mg ions led to the thermal stabilization of the β-TCP phase by suppressing the phase transition into α-TCP when sintered at 1200 °C. Moreover, the co-presence of Mg ions significantly improved the hardness of Sr-doped HAP from 3.74 to 5.02 GPa. Sr,Mg-HAP dental inserts were found to achieve sufficient bonding (13.53 MPa) through the micromechanical interlocking with Z250 dental composite and Single Bond Universal dental adhesive applied with a total etch approach. The SBS values obtained for the SrMg-HAP insert were similar to the literature data on bonding ability with human dentin, indicating that binary doped Sr,Mg-HAP ceramics present a promising material for application in restorative dentistry as dentin substitutes.",
journal = "Ceramics International",
title = "Sr,Mg co-doping of calcium hydroxyapatite: Hydrothermal synthesis, processing, characterization and possible application as dentin substitutes",
pages = "11165-11155",
number = "8",
volume = "48",
doi = "10.1016/j.ceramint.2021.12.335"
}

Matić, T., Zebić, M. L., Miletić, V., Cvijović-Alagić, I., Petrović, R., Janaćković, Đ.,& Veljović, Đ.. (2022). Sr,Mg co-doping of calcium hydroxyapatite: Hydrothermal synthesis, processing, characterization and possible application as dentin substitutes. in Ceramics International, 48(8), 11155-11165.
https://doi.org/10.1016/j.ceramint.2021.12.335

Matić T, Zebić ML, Miletić V, Cvijović-Alagić I, Petrović R, Janaćković Đ, Veljović Đ. Sr,Mg co-doping of calcium hydroxyapatite: Hydrothermal synthesis, processing, characterization and possible application as dentin substitutes. in Ceramics International. 2022;48(8):11155-11165.
doi:10.1016/j.ceramint.2021.12.335 .

Matić, Tamara, Zebić, M. Ležaja, Miletić, Vesna, Cvijović-Alagić, Ivana, Petrović, Rada, Janaćković, Đorđe, Veljović, Đorđe, "Sr,Mg co-doping of calcium hydroxyapatite: Hydrothermal synthesis, processing, characterization and possible application as dentin substitutes" in Ceramics International, 48, no. 8 (2022):11155-11165,
https://doi.org/10.1016/j.ceramint.2021.12.335 . .

TY  - CONF
AU  - Matić, Tamara
AU  - Zebić, Maja L.
AU  - Miletić, Vesna
AU  - Petrović, Rada
AU  - Janaćković, Đorđe
AU  - Veljović, Đorđe
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6674
AB  - Tooth caries presents one of the most common diseases worldwide, and its treatment involves
removal of the decayed tooth structure, and the cavity restoration using restorative dental materials. Resin based composites (RBCs) are the most commonly used restorative material in practice owing to their great aesthetic appearance allowing the clinicians to adapt the nuance of the restoration to the patient’s tooth color. However, the RBCs harden by the polymerization of monomers that leads to the polymerization shrinkage of the restoration, leaving the micro-gaps at the teeth-restorations interface which allows the secondary caries formation.
PB  - Belgrade : Serbian Academy of Sciences and Arts
C3  - Program & Book of Abstracts / Second International Conference on Electron Microscopy of Nanostructures ELMINA 2022, August 22nd-26th Belgrade, Serbia
T1  - Hydroxyapatite-based Bioceramic Dental Inserts as Dentin Substitute
EP  - 151
SP  - 150
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6674
ER  - 

@conference{
author = "Matić, Tamara and Zebić, Maja L. and Miletić, Vesna and Petrović, Rada and Janaćković, Đorđe and Veljović, Đorđe",
year = "2022",
abstract = "Tooth caries presents one of the most common diseases worldwide, and its treatment involves
removal of the decayed tooth structure, and the cavity restoration using restorative dental materials. Resin based composites (RBCs) are the most commonly used restorative material in practice owing to their great aesthetic appearance allowing the clinicians to adapt the nuance of the restoration to the patient’s tooth color. However, the RBCs harden by the polymerization of monomers that leads to the polymerization shrinkage of the restoration, leaving the micro-gaps at the teeth-restorations interface which allows the secondary caries formation.",
publisher = "Belgrade : Serbian Academy of Sciences and Arts",
journal = "Program & Book of Abstracts / Second International Conference on Electron Microscopy of Nanostructures ELMINA 2022, August 22nd-26th Belgrade, Serbia",
title = "Hydroxyapatite-based Bioceramic Dental Inserts as Dentin Substitute",
pages = "151-150",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6674"
}

Matić, T., Zebić, M. L., Miletić, V., Petrović, R., Janaćković, Đ.,& Veljović, Đ.. (2022). Hydroxyapatite-based Bioceramic Dental Inserts as Dentin Substitute. in Program & Book of Abstracts / Second International Conference on Electron Microscopy of Nanostructures ELMINA 2022, August 22nd-26th Belgrade, Serbia
Belgrade : Serbian Academy of Sciences and Arts., 150-151.
https://hdl.handle.net/21.15107/rcub_technorep_6674

Matić T, Zebić ML, Miletić V, Petrović R, Janaćković Đ, Veljović Đ. Hydroxyapatite-based Bioceramic Dental Inserts as Dentin Substitute. in Program & Book of Abstracts / Second International Conference on Electron Microscopy of Nanostructures ELMINA 2022, August 22nd-26th Belgrade, Serbia. 2022;:150-151.
https://hdl.handle.net/21.15107/rcub_technorep_6674 .

Matić, Tamara, Zebić, Maja L., Miletić, Vesna, Petrović, Rada, Janaćković, Đorđe, Veljović, Đorđe, "Hydroxyapatite-based Bioceramic Dental Inserts as Dentin Substitute" in Program & Book of Abstracts / Second International Conference on Electron Microscopy of Nanostructures ELMINA 2022, August 22nd-26th Belgrade, Serbia (2022):150-151,
https://hdl.handle.net/21.15107/rcub_technorep_6674 .

TY  - CONF
AU  - Matić, Tamara
AU  - Zebić, Maja L.
AU  - Miletić, Vesna
AU  - Petrović, Rada
AU  - Janaćković, Đorđe
AU  - Veljović, Đorđe
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6680
PB  - Belgrade : Institut za multidisciplinarna istraživanja
C3  - Programme and the Book of Abstracts / 6th Conference of The Serbian Society for Ceramic Materials, 6CSCS-2022, June 28-29, 2022, Belgrade, Serbia
T1  - THE INFLUENCE OF HYDROTHERMAL SYNTHESIS TEMPERATURE OF MAGNESIUM DOPED HYDROXYAPATITE ON ITS APPLICATION AS DENTIN SUBSTITUTE
EP  - 37
SP  - 36
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6680
ER  - 

@conference{
author = "Matić, Tamara and Zebić, Maja L. and Miletić, Vesna and Petrović, Rada and Janaćković, Đorđe and Veljović, Đorđe",
year = "2022",
publisher = "Belgrade : Institut za multidisciplinarna istraživanja",
journal = "Programme and the Book of Abstracts / 6th Conference of The Serbian Society for Ceramic Materials, 6CSCS-2022, June 28-29, 2022, Belgrade, Serbia",
title = "THE INFLUENCE OF HYDROTHERMAL SYNTHESIS TEMPERATURE OF MAGNESIUM DOPED HYDROXYAPATITE ON ITS APPLICATION AS DENTIN SUBSTITUTE",
pages = "37-36",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6680"
}

Matić, T., Zebić, M. L., Miletić, V., Petrović, R., Janaćković, Đ.,& Veljović, Đ.. (2022). THE INFLUENCE OF HYDROTHERMAL SYNTHESIS TEMPERATURE OF MAGNESIUM DOPED HYDROXYAPATITE ON ITS APPLICATION AS DENTIN SUBSTITUTE. in Programme and the Book of Abstracts / 6th Conference of The Serbian Society for Ceramic Materials, 6CSCS-2022, June 28-29, 2022, Belgrade, Serbia
Belgrade : Institut za multidisciplinarna istraživanja., 36-37.
https://hdl.handle.net/21.15107/rcub_technorep_6680

Matić T, Zebić ML, Miletić V, Petrović R, Janaćković Đ, Veljović Đ. THE INFLUENCE OF HYDROTHERMAL SYNTHESIS TEMPERATURE OF MAGNESIUM DOPED HYDROXYAPATITE ON ITS APPLICATION AS DENTIN SUBSTITUTE. in Programme and the Book of Abstracts / 6th Conference of The Serbian Society for Ceramic Materials, 6CSCS-2022, June 28-29, 2022, Belgrade, Serbia. 2022;:36-37.
https://hdl.handle.net/21.15107/rcub_technorep_6680 .

Matić, Tamara, Zebić, Maja L., Miletić, Vesna, Petrović, Rada, Janaćković, Đorđe, Veljović, Đorđe, "THE INFLUENCE OF HYDROTHERMAL SYNTHESIS TEMPERATURE OF MAGNESIUM DOPED HYDROXYAPATITE ON ITS APPLICATION AS DENTIN SUBSTITUTE" in Programme and the Book of Abstracts / 6th Conference of The Serbian Society for Ceramic Materials, 6CSCS-2022, June 28-29, 2022, Belgrade, Serbia (2022):36-37,
https://hdl.handle.net/21.15107/rcub_technorep_6680 .

TY  - JOUR
AU  - Kazuz, Abdul
AU  - Radovanović, Željko
AU  - Veljović, Đorđe
AU  - Kojić, Vesna
AU  - Jakimov, Dimitar
AU  - Vlajić-Tovilović, Tamara
AU  - Miletić, Vesna
AU  - Petrović, Rada
AU  - Janaćković, Đorđe
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5143
AB  - α-Tricalcium phosphate/fluorapatite (α-TCP/FAp) mixed powders were prepared in order to obtain dental root canal filling cements. Different liquids for cement pastes have been investigated and the most suitable one for obtaining rheologically optimal pastes was chosen for further analysis. Morphological changes in the cement materials as a consequence of the formation of hydroxyapatite (HAp) after the immersion in a simulated body fluid (SBF), an influence on the cell viability, and final success of the filling were investigated by field emission scanning electron microscopy. Treatment of the α-TCP/FAp mixtures in SBF at 37 °C resulted in a complete transformation of α-TCP into HAp after 10 days, while the exposure of MRC-5 human and L929 animal fibroblast cells to the cement showed complete absence of cytotoxicity. The root canal of an extracted tooth was filled with the α-TCP/FAp cement containing 5 wt.% of FAp and relatively strong adhesion between the cement and dentine was observed after 48 h. The same cement material was immersed during 10 days in SBF and after that both human and animal fibroblast cells during in vitro MTT tests showed higher cell viability compared to the control sample. These findings lead to a conclusion that the α-TCP/FAp based cement demonstrates potential for further development towards dental cement application.
PB  - University of Novi Sad, Faculty of Technology
T2  - Processing and Application of Ceramics
T1  - α-Tricalcium phosphate/fluorapatite-based cement – Promising dental root canal filling material
EP  - 29
IS  - 1
SP  - 22
VL  - 16
DO  - 10.2298/PAC2201022K
ER  - 

@article{
author = "Kazuz, Abdul and Radovanović, Željko and Veljović, Đorđe and Kojić, Vesna and Jakimov, Dimitar and Vlajić-Tovilović, Tamara and Miletić, Vesna and Petrović, Rada and Janaćković, Đorđe",
year = "2022",
abstract = "α-Tricalcium phosphate/fluorapatite (α-TCP/FAp) mixed powders were prepared in order to obtain dental root canal filling cements. Different liquids for cement pastes have been investigated and the most suitable one for obtaining rheologically optimal pastes was chosen for further analysis. Morphological changes in the cement materials as a consequence of the formation of hydroxyapatite (HAp) after the immersion in a simulated body fluid (SBF), an influence on the cell viability, and final success of the filling were investigated by field emission scanning electron microscopy. Treatment of the α-TCP/FAp mixtures in SBF at 37 °C resulted in a complete transformation of α-TCP into HAp after 10 days, while the exposure of MRC-5 human and L929 animal fibroblast cells to the cement showed complete absence of cytotoxicity. The root canal of an extracted tooth was filled with the α-TCP/FAp cement containing 5 wt.% of FAp and relatively strong adhesion between the cement and dentine was observed after 48 h. The same cement material was immersed during 10 days in SBF and after that both human and animal fibroblast cells during in vitro MTT tests showed higher cell viability compared to the control sample. These findings lead to a conclusion that the α-TCP/FAp based cement demonstrates potential for further development towards dental cement application.",
publisher = "University of Novi Sad, Faculty of Technology",
journal = "Processing and Application of Ceramics",
title = "α-Tricalcium phosphate/fluorapatite-based cement – Promising dental root canal filling material",
pages = "29-22",
number = "1",
volume = "16",
doi = "10.2298/PAC2201022K"
}

Kazuz, A., Radovanović, Ž., Veljović, Đ., Kojić, V., Jakimov, D., Vlajić-Tovilović, T., Miletić, V., Petrović, R.,& Janaćković, Đ.. (2022). α-Tricalcium phosphate/fluorapatite-based cement – Promising dental root canal filling material. in Processing and Application of Ceramics
University of Novi Sad, Faculty of Technology., 16(1), 22-29.
https://doi.org/10.2298/PAC2201022K

Kazuz A, Radovanović Ž, Veljović Đ, Kojić V, Jakimov D, Vlajić-Tovilović T, Miletić V, Petrović R, Janaćković Đ. α-Tricalcium phosphate/fluorapatite-based cement – Promising dental root canal filling material. in Processing and Application of Ceramics. 2022;16(1):22-29.
doi:10.2298/PAC2201022K .

Kazuz, Abdul, Radovanović, Željko, Veljović, Đorđe, Kojić, Vesna, Jakimov, Dimitar, Vlajić-Tovilović, Tamara, Miletić, Vesna, Petrović, Rada, Janaćković, Đorđe, "α-Tricalcium phosphate/fluorapatite-based cement – Promising dental root canal filling material" in Processing and Application of Ceramics, 16, no. 1 (2022):22-29,
https://doi.org/10.2298/PAC2201022K . .

TY  - CONF
AU  - Matić, Tamara
AU  - Ležaja Zebić, Maja
AU  - Miletić, Vesna
AU  - Petrović, Rada
AU  - Janaćković, Đorđe
AU  - Veljović, Đorđe
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6679
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of abstracts / Nineteenth Young Researchers' Conference Materials Science and Engineering, December 1-3, 2021, Belgrade, Serbia
T1  - Dental inserts based on calcium hydroxyapatite: The influence of cation doping
SP  - 13
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6679
ER  - 

@conference{
author = "Matić, Tamara and Ležaja Zebić, Maja and Miletić, Vesna and Petrović, Rada and Janaćković, Đorđe and Veljović, Đorđe",
year = "2021",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of abstracts / Nineteenth Young Researchers' Conference Materials Science and Engineering, December 1-3, 2021, Belgrade, Serbia",
title = "Dental inserts based on calcium hydroxyapatite: The influence of cation doping",
pages = "13",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6679"
}

Matić, T., Ležaja Zebić, M., Miletić, V., Petrović, R., Janaćković, Đ.,& Veljović, Đ.. (2021). Dental inserts based on calcium hydroxyapatite: The influence of cation doping. in Program and the Book of abstracts / Nineteenth Young Researchers' Conference Materials Science and Engineering, December 1-3, 2021, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 13.
https://hdl.handle.net/21.15107/rcub_technorep_6679

Matić T, Ležaja Zebić M, Miletić V, Petrović R, Janaćković Đ, Veljović Đ. Dental inserts based on calcium hydroxyapatite: The influence of cation doping. in Program and the Book of abstracts / Nineteenth Young Researchers' Conference Materials Science and Engineering, December 1-3, 2021, Belgrade, Serbia. 2021;:13.
https://hdl.handle.net/21.15107/rcub_technorep_6679 .

Matić, Tamara, Ležaja Zebić, Maja, Miletić, Vesna, Petrović, Rada, Janaćković, Đorđe, Veljović, Đorđe, "Dental inserts based on calcium hydroxyapatite: The influence of cation doping" in Program and the Book of abstracts / Nineteenth Young Researchers' Conference Materials Science and Engineering, December 1-3, 2021, Belgrade, Serbia (2021):13,
https://hdl.handle.net/21.15107/rcub_technorep_6679 .

TY  - CONF
AU  - Matić, Tamara
AU  - Ležaja Zebić, Maja
AU  - Miletić, Vesna
AU  - Petrović, Rada
AU  - Janaćković, Đorđe
AU  - Veljović, Đorđe
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7315
AB  - Decayed or damaged tooth structure is widely being repaired with the resin
based dental composites (RBCs) in the clinical practice. However, relatively high failure rate
and short lifespan are common in the case of the larger posterior teeth restorations,
caused by the polymerization shrinkage of RBCs. In order to reduce the polymerization
shrinkage inorganic dental inserts were introduced. The aim of this study was to fabricate
dental inserts based on hydroxyapatite doped with 5 mol. % of magnesium ions (MgHAP)
and determine their bonding ability with a restorative material widely used in the clinical
practice – Clearfil Universal adhesive. The MgHAP powder and insert were characterized
using energy dispersive X-ray (EDX) analysis, X-ray diffraction (XRD) analysis and scanning
electron microscopy (FE-SEM). Bonding ability of the inserts with restorative material was
measured by shear bond strength (SBS) test, and the type of fracture was determined by
the optical microscope. The obtained mean SBS value of the MgHAP inserts was 12.7 MPa,
with mostly cohesive type of the fracture present. These inserts present promising dentin
substitutes for application in the restorative dentistry.
PB  - Belgrade : Institut za istraživanja i projektovanja u privredi
C3  - Abstract proceedings / Young Researches Conference 2020, YOURS 2020, 28th September 2020, Belgrade
T1  - Bonding ability of magnesium doped hydroxyapatite based insert with Clearfil dental adhesive
SP  - 40
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7315
ER  - 

@conference{
author = "Matić, Tamara and Ležaja Zebić, Maja and Miletić, Vesna and Petrović, Rada and Janaćković, Đorđe and Veljović, Đorđe",
year = "2020",
abstract = "Decayed or damaged tooth structure is widely being repaired with the resin
based dental composites (RBCs) in the clinical practice. However, relatively high failure rate
and short lifespan are common in the case of the larger posterior teeth restorations,
caused by the polymerization shrinkage of RBCs. In order to reduce the polymerization
shrinkage inorganic dental inserts were introduced. The aim of this study was to fabricate
dental inserts based on hydroxyapatite doped with 5 mol. % of magnesium ions (MgHAP)
and determine their bonding ability with a restorative material widely used in the clinical
practice – Clearfil Universal adhesive. The MgHAP powder and insert were characterized
using energy dispersive X-ray (EDX) analysis, X-ray diffraction (XRD) analysis and scanning
electron microscopy (FE-SEM). Bonding ability of the inserts with restorative material was
measured by shear bond strength (SBS) test, and the type of fracture was determined by
the optical microscope. The obtained mean SBS value of the MgHAP inserts was 12.7 MPa,
with mostly cohesive type of the fracture present. These inserts present promising dentin
substitutes for application in the restorative dentistry.",
publisher = "Belgrade : Institut za istraživanja i projektovanja u privredi",
journal = "Abstract proceedings / Young Researches Conference 2020, YOURS 2020, 28th September 2020, Belgrade",
title = "Bonding ability of magnesium doped hydroxyapatite based insert with Clearfil dental adhesive",
pages = "40",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7315"
}

Matić, T., Ležaja Zebić, M., Miletić, V., Petrović, R., Janaćković, Đ.,& Veljović, Đ.. (2020). Bonding ability of magnesium doped hydroxyapatite based insert with Clearfil dental adhesive. in Abstract proceedings / Young Researches Conference 2020, YOURS 2020, 28th September 2020, Belgrade
Belgrade : Institut za istraživanja i projektovanja u privredi., 40.
https://hdl.handle.net/21.15107/rcub_technorep_7315

Matić T, Ležaja Zebić M, Miletić V, Petrović R, Janaćković Đ, Veljović Đ. Bonding ability of magnesium doped hydroxyapatite based insert with Clearfil dental adhesive. in Abstract proceedings / Young Researches Conference 2020, YOURS 2020, 28th September 2020, Belgrade. 2020;:40.
https://hdl.handle.net/21.15107/rcub_technorep_7315 .

Matić, Tamara, Ležaja Zebić, Maja, Miletić, Vesna, Petrović, Rada, Janaćković, Đorđe, Veljović, Đorđe, "Bonding ability of magnesium doped hydroxyapatite based insert with Clearfil dental adhesive" in Abstract proceedings / Young Researches Conference 2020, YOURS 2020, 28th September 2020, Belgrade (2020):40,
https://hdl.handle.net/21.15107/rcub_technorep_7315 .

TY  - JOUR
AU  - Kazuz, A.
AU  - Radovanović, Željko
AU  - Veljović, Đorđe
AU  - Kojić, Vesna
AU  - Miletić, Vesna
AU  - Petrović, Rada
AU  - Janaćković, Đorđe
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4371
AB  - Composite cements based on alpha-tricalcium phosphate (alpha-TCP) and nanostructured fluorapatite (FAp), alpha-TCP/FAp, appropriate for dental usage as root canal filling material, have been prepared with the improved mechanical properties and biocompatibility. The influence of FAp concentration on the composite cement properties was investigated. The processing conditions for FAp powders synthesis were optimized and the powder with optimal properties was chosen to obtain alpha-TCP/FAp composite types of cement alpha-TCP powder was prepared by calcination of hydrothermally synthesized hydroxyapatite (HAp) at 1500 degrees C for 2 h. Morphology and phase composition of powders were investigated by X-ray diffraction (XRD), Fourier transformed infrared spectroscopy (FTIR), Field emission scanning electron microscopy (FESEM), and energy dispersive X-ray spectroscopy (EDS). Soaking of alpha-TCP/FAp specimens in simulated body fluid (SBF) affected the successful transformation of alpha-TCP into HAp, while the compressive test revealed the influence of this transformation and FAp content on the mechanical properties of the composites. Specimen containing 5% of FAp after 10 days in SBF showed the highest compressive strength. In vitro MIT and DET biocompatibility tests, performed in the culture of MRC-5 human fibroblast cells, revealed that alpha-TCP/FAp had no cytotoxic effect. These initial findings showed that alpha-TCP/FAp composite cements could yield favorable mechanical properties with no adverse effect on biocompatibility.
PB  - Elsevier Sci Ltd, Oxford
T2  - Ceramics International
T1  - alpha-Tricalcium phosphate/fluorapatite based composite cements: Synthesis, mechanical properties, and biocompatibility
IS  - 16
VL  - 46
DO  - 10.1016/j.ceramint.2020.06.301
ER  - 

@article{
author = "Kazuz, A. and Radovanović, Željko and Veljović, Đorđe and Kojić, Vesna and Miletić, Vesna and Petrović, Rada and Janaćković, Đorđe",
year = "2020",
abstract = "Composite cements based on alpha-tricalcium phosphate (alpha-TCP) and nanostructured fluorapatite (FAp), alpha-TCP/FAp, appropriate for dental usage as root canal filling material, have been prepared with the improved mechanical properties and biocompatibility. The influence of FAp concentration on the composite cement properties was investigated. The processing conditions for FAp powders synthesis were optimized and the powder with optimal properties was chosen to obtain alpha-TCP/FAp composite types of cement alpha-TCP powder was prepared by calcination of hydrothermally synthesized hydroxyapatite (HAp) at 1500 degrees C for 2 h. Morphology and phase composition of powders were investigated by X-ray diffraction (XRD), Fourier transformed infrared spectroscopy (FTIR), Field emission scanning electron microscopy (FESEM), and energy dispersive X-ray spectroscopy (EDS). Soaking of alpha-TCP/FAp specimens in simulated body fluid (SBF) affected the successful transformation of alpha-TCP into HAp, while the compressive test revealed the influence of this transformation and FAp content on the mechanical properties of the composites. Specimen containing 5% of FAp after 10 days in SBF showed the highest compressive strength. In vitro MIT and DET biocompatibility tests, performed in the culture of MRC-5 human fibroblast cells, revealed that alpha-TCP/FAp had no cytotoxic effect. These initial findings showed that alpha-TCP/FAp composite cements could yield favorable mechanical properties with no adverse effect on biocompatibility.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Ceramics International",
title = "alpha-Tricalcium phosphate/fluorapatite based composite cements: Synthesis, mechanical properties, and biocompatibility",
number = "16",
volume = "46",
doi = "10.1016/j.ceramint.2020.06.301"
}

Kazuz, A., Radovanović, Ž., Veljović, Đ., Kojić, V., Miletić, V., Petrović, R.,& Janaćković, Đ.. (2020). alpha-Tricalcium phosphate/fluorapatite based composite cements: Synthesis, mechanical properties, and biocompatibility. in Ceramics International
Elsevier Sci Ltd, Oxford., 46(16).
https://doi.org/10.1016/j.ceramint.2020.06.301

Kazuz A, Radovanović Ž, Veljović Đ, Kojić V, Miletić V, Petrović R, Janaćković Đ. alpha-Tricalcium phosphate/fluorapatite based composite cements: Synthesis, mechanical properties, and biocompatibility. in Ceramics International. 2020;46(16).
doi:10.1016/j.ceramint.2020.06.301 .

Kazuz, A., Radovanović, Željko, Veljović, Đorđe, Kojić, Vesna, Miletić, Vesna, Petrović, Rada, Janaćković, Đorđe, "alpha-Tricalcium phosphate/fluorapatite based composite cements: Synthesis, mechanical properties, and biocompatibility" in Ceramics International, 46, no. 16 (2020),
https://doi.org/10.1016/j.ceramint.2020.06.301 . .

TY  - JOUR
AU  - Ayoub, Giuma
AU  - Ležaja-Zebić, Maja
AU  - Miletić, Vesna
AU  - Petrović, Rada
AU  - Veljović, Đorđe
AU  - Janaćković, Đorđe
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4476
AB  - The application of sintered calcium phosphate dental inserts in the central part of tooth cavities can reduce amount of embedded dental composite and polymerization shrinkage of final dental fillings. The aim of this study was to analyze comparatively physico-chemical and mechanical properties of dental inserts and shear bond strength (SBS) between three dissimilar hydroxyapatite-based dental inserts and different restorative materials, after application of different clinical protocols. Starting from two different hydroxyapatite nano powders and nanostructured stabilized zirconia (YSZ), monophasic two-step sintered dense HAp inserts (TSSHAp), biphasic single-step sintered controlled porous inserts (HAp/TCp), and single-step sintered reinforced HAp/YSZ inserts were processed and characterized. Obvious differences in the microstructure of inserts surface were visualized after etching with 37% phosphoric acid. Fracture toughness of sintered inserts was ranged between 1.01 and 1.85 MPam(1/2) (maximum value in the case of HAp/YSZ), while hardness values were in the range of 3.71-5.22 GPa (maximum value in the case of TSSHAp). Acid etching before application improved SBS between inserts and Maxcem compared to direct cement application. TSSHAp and HAP/TCp inserts showed comparable and relatively high SBS values, certainly higher compared to HAp/YSZ inserts. Slightly higher SBS values were measured in the case of TSSHAp insert group, and the highest mean SBS value of 18.51 MPa was determined between TSSHAp inserts and Filtek Z250_SBU following the "self-etch" protocol.
PB  - Wiley, Hoboken
T2  - Journal of Biomedical Materials Research Part B-Applied Biomaterials
T1  - Dissimilar sintered calcium phosphate dental inserts as dentine substitutes: Shear bond strength to restorative materials
EP  - 2470
IS  - 6
SP  - 2461
VL  - 108
DO  - 10.1002/jbm.b.34578
ER  - 

@article{
author = "Ayoub, Giuma and Ležaja-Zebić, Maja and Miletić, Vesna and Petrović, Rada and Veljović, Đorđe and Janaćković, Đorđe",
year = "2020",
abstract = "The application of sintered calcium phosphate dental inserts in the central part of tooth cavities can reduce amount of embedded dental composite and polymerization shrinkage of final dental fillings. The aim of this study was to analyze comparatively physico-chemical and mechanical properties of dental inserts and shear bond strength (SBS) between three dissimilar hydroxyapatite-based dental inserts and different restorative materials, after application of different clinical protocols. Starting from two different hydroxyapatite nano powders and nanostructured stabilized zirconia (YSZ), monophasic two-step sintered dense HAp inserts (TSSHAp), biphasic single-step sintered controlled porous inserts (HAp/TCp), and single-step sintered reinforced HAp/YSZ inserts were processed and characterized. Obvious differences in the microstructure of inserts surface were visualized after etching with 37% phosphoric acid. Fracture toughness of sintered inserts was ranged between 1.01 and 1.85 MPam(1/2) (maximum value in the case of HAp/YSZ), while hardness values were in the range of 3.71-5.22 GPa (maximum value in the case of TSSHAp). Acid etching before application improved SBS between inserts and Maxcem compared to direct cement application. TSSHAp and HAP/TCp inserts showed comparable and relatively high SBS values, certainly higher compared to HAp/YSZ inserts. Slightly higher SBS values were measured in the case of TSSHAp insert group, and the highest mean SBS value of 18.51 MPa was determined between TSSHAp inserts and Filtek Z250_SBU following the "self-etch" protocol.",
publisher = "Wiley, Hoboken",
journal = "Journal of Biomedical Materials Research Part B-Applied Biomaterials",
title = "Dissimilar sintered calcium phosphate dental inserts as dentine substitutes: Shear bond strength to restorative materials",
pages = "2470-2461",
number = "6",
volume = "108",
doi = "10.1002/jbm.b.34578"
}

Ayoub, G., Ležaja-Zebić, M., Miletić, V., Petrović, R., Veljović, Đ.,& Janaćković, Đ.. (2020). Dissimilar sintered calcium phosphate dental inserts as dentine substitutes: Shear bond strength to restorative materials. in Journal of Biomedical Materials Research Part B-Applied Biomaterials
Wiley, Hoboken., 108(6), 2461-2470.
https://doi.org/10.1002/jbm.b.34578

Ayoub G, Ležaja-Zebić M, Miletić V, Petrović R, Veljović Đ, Janaćković Đ. Dissimilar sintered calcium phosphate dental inserts as dentine substitutes: Shear bond strength to restorative materials. in Journal of Biomedical Materials Research Part B-Applied Biomaterials. 2020;108(6):2461-2470.
doi:10.1002/jbm.b.34578 .

Ayoub, Giuma, Ležaja-Zebić, Maja, Miletić, Vesna, Petrović, Rada, Veljović, Đorđe, Janaćković, Đorđe, "Dissimilar sintered calcium phosphate dental inserts as dentine substitutes: Shear bond strength to restorative materials" in Journal of Biomedical Materials Research Part B-Applied Biomaterials, 108, no. 6 (2020):2461-2470,
https://doi.org/10.1002/jbm.b.34578 . .

TY  - JOUR
AU  - Stasić, Jovana
AU  - Selaković, Nenad
AU  - Puač, Nevena
AU  - Miletić, Maja
AU  - Malović, Gordana
AU  - Petrović, Zoran Lj
AU  - Veljović, Đorđe
AU  - Miletić, Vesna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5048
AB  - The study aims to evaluate the effects of non-thermal atmospheric plasma (NTAP) treatments on dentin wetting and surface free energy (SFE) and compare the effects of NTAP treatment, etch-and-rinse, and self-etch protocols for application of universal adhesives. Materials and methods: Mid-coronal dentin of intact third molars was used to measure contact angles of distilled water, ethylene-glycol, and diiodomethane and calculate SFE following different NTAP preset treatments (feeding gas consisting of pure He, He + 1% O 2 , He + 1.5% O 2 ), power input (1 or 3 W), and tip-to-surface distance (2, 4, or 8 mm). Contact angles of reference liquids and SFE of dentin following He + 1.5% O 2 at 3-W and 4-mm treatment was compared to phosphoric acid etching. Contact angles of Single Bond Universal (SBU; 3M ESPE) and Clearfil Universal Bond (CUB; Kuraray Noritake) were measured following NTAP, etch-and-rinse, and self-etch protocols. Results: NTAP significantly reduced contact angles of reference liquids and increased dentin SFE compared to untreated dentin (p < 0.05). O 2 intensified the effect of He NTAP (p < 0.05). NTAP and phosphoric acid increased dentin polarity and Lewis base surface characteristics. Phosphoric acid increased contact angles of adhesives compared to the self-etch protocol (p < 0.05). NTAP resulted in lower adhesive contact angles than phosphoric acid, the difference being statistically significant for CUB (p [removed] 0.05). Conclusions: He NTAP with and without O 2 increased dentin wetting and SFE, surpassing the effect of phosphoric acid and lowering adhesive contact angles. NTAP produced no apparent micro-morphological changes on dentin surface comparable to acid etching. Clinical significance: NTAP treatment of dentin prior to adhesive application increases dentin wetting and surface free energy facilitating better adhesive distribution on dentin surface compared to phosphoric acid etching and similar to the “self-etch” application protocol.
PB  - Springer Verlag
T2  - Clinical Oral Investigations
T1  - Effects of non-thermal atmospheric plasma treatment on dentin wetting and surface free energy for application of universal adhesives
EP  - 1396
IS  - 3
SP  - 1383
VL  - 23
DO  - 10.1007/s00784-018-2563-2
ER  - 

@article{
author = "Stasić, Jovana and Selaković, Nenad and Puač, Nevena and Miletić, Maja and Malović, Gordana and Petrović, Zoran Lj and Veljović, Đorđe and Miletić, Vesna",
year = "2019",
abstract = "The study aims to evaluate the effects of non-thermal atmospheric plasma (NTAP) treatments on dentin wetting and surface free energy (SFE) and compare the effects of NTAP treatment, etch-and-rinse, and self-etch protocols for application of universal adhesives. Materials and methods: Mid-coronal dentin of intact third molars was used to measure contact angles of distilled water, ethylene-glycol, and diiodomethane and calculate SFE following different NTAP preset treatments (feeding gas consisting of pure He, He + 1% O 2 , He + 1.5% O 2 ), power input (1 or 3 W), and tip-to-surface distance (2, 4, or 8 mm). Contact angles of reference liquids and SFE of dentin following He + 1.5% O 2 at 3-W and 4-mm treatment was compared to phosphoric acid etching. Contact angles of Single Bond Universal (SBU; 3M ESPE) and Clearfil Universal Bond (CUB; Kuraray Noritake) were measured following NTAP, etch-and-rinse, and self-etch protocols. Results: NTAP significantly reduced contact angles of reference liquids and increased dentin SFE compared to untreated dentin (p < 0.05). O 2 intensified the effect of He NTAP (p < 0.05). NTAP and phosphoric acid increased dentin polarity and Lewis base surface characteristics. Phosphoric acid increased contact angles of adhesives compared to the self-etch protocol (p < 0.05). NTAP resulted in lower adhesive contact angles than phosphoric acid, the difference being statistically significant for CUB (p [removed] 0.05). Conclusions: He NTAP with and without O 2 increased dentin wetting and SFE, surpassing the effect of phosphoric acid and lowering adhesive contact angles. NTAP produced no apparent micro-morphological changes on dentin surface comparable to acid etching. Clinical significance: NTAP treatment of dentin prior to adhesive application increases dentin wetting and surface free energy facilitating better adhesive distribution on dentin surface compared to phosphoric acid etching and similar to the “self-etch” application protocol.",
publisher = "Springer Verlag",
journal = "Clinical Oral Investigations",
title = "Effects of non-thermal atmospheric plasma treatment on dentin wetting and surface free energy for application of universal adhesives",
pages = "1396-1383",
number = "3",
volume = "23",
doi = "10.1007/s00784-018-2563-2"
}

Stasić, J., Selaković, N., Puač, N., Miletić, M., Malović, G., Petrović, Z. L., Veljović, Đ.,& Miletić, V.. (2019). Effects of non-thermal atmospheric plasma treatment on dentin wetting and surface free energy for application of universal adhesives. in Clinical Oral Investigations
Springer Verlag., 23(3), 1383-1396.
https://doi.org/10.1007/s00784-018-2563-2

Stasić J, Selaković N, Puač N, Miletić M, Malović G, Petrović ZL, Veljović Đ, Miletić V. Effects of non-thermal atmospheric plasma treatment on dentin wetting and surface free energy for application of universal adhesives. in Clinical Oral Investigations. 2019;23(3):1383-1396.
doi:10.1007/s00784-018-2563-2 .

Stasić, Jovana, Selaković, Nenad, Puač, Nevena, Miletić, Maja, Malović, Gordana, Petrović, Zoran Lj, Veljović, Đorđe, Miletić, Vesna, "Effects of non-thermal atmospheric plasma treatment on dentin wetting and surface free energy for application of universal adhesives" in Clinical Oral Investigations, 23, no. 3 (2019):1383-1396,
https://doi.org/10.1007/s00784-018-2563-2 . .

TY  - JOUR
AU  - Mitrović, Aleksandra
AU  - Tanasić, Ivan
AU  - Mitrović, Nenad
AU  - Miletić, Vesna
AU  - Bakić, Gordana
AU  - Milošević, Miloš
AU  - Antonović, Dušan
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5878
AB  - The study showed an application of the 3 D Digital Image Correlation Method (3 D-DIC) for detection of von Mises strain in samples of the self-etch, self-adhesive resin based cement (RBC). The aim was to determine and compare strain in the self-cured and light-cured Maxcem Elite, furthermore to investigate the hardness of these two cement-types. The experiment was carried out using two groups of Maxcem Elite (Kerr, Orange, CA, USA) samples; each tested group includes five (o5 x 2 mm sized) samples, for both self-curing and light-curing mode. All samples were prepared by filling teflon ring-type molds. In addition, Vickers micro-hardness was measured for all samples. Maxcem Elite showed similar maximum strain values from 10% to 12% for both groups. Besides the maximum strain value, the 3 D-DIC method also enabled monitoring the change of strain field even after the recommended polymerization time. This method has shown that the polymerization shrinkage continues even after 10 min which disagreed with manufacturer's suggestion. Group II showed maximum strain values of 12% in the peripheral zone after 10 min, in the last Stage (Stage 60). Statistically significant difference was not found in the overall strain between self- and light-cured Maxcem Elite neither peripherally (p = 0.118) nor centrally (p = 0.879). However, statistical significance was found in strain regarding central and peripheral zone in both, self-cured (p = 0.020) and light-cured (p = 0.002) Maxcem Elite. The mean von Mises strain values in the periphery of the samples (Section 0) were significantly higher compared to strain values in the center of the samples (for Section 1 and 2). The last stage (Stage 60) of the light-cured Maxcem Elite polymerization showed significantly higher values of von Mises strain compared to initial stage (Stage 0). Higher values of micro-hardness were noticed on the surfaces directly exposed to LED lamp after performing measurements of micro-hardness on light-cured samples.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Journal of Adhesion Science & Technology
T1  - Analysis of the strain and hardness in self-cured and light-cured self-adhesive resin based cement
EP  - 2695
IS  - 24
SP  - 2684
VL  - 33
DO  - 10.1080/01694243.2019.1654221
ER  - 

@article{
author = "Mitrović, Aleksandra and Tanasić, Ivan and Mitrović, Nenad and Miletić, Vesna and Bakić, Gordana and Milošević, Miloš and Antonović, Dušan",
year = "2019",
abstract = "The study showed an application of the 3 D Digital Image Correlation Method (3 D-DIC) for detection of von Mises strain in samples of the self-etch, self-adhesive resin based cement (RBC). The aim was to determine and compare strain in the self-cured and light-cured Maxcem Elite, furthermore to investigate the hardness of these two cement-types. The experiment was carried out using two groups of Maxcem Elite (Kerr, Orange, CA, USA) samples; each tested group includes five (o5 x 2 mm sized) samples, for both self-curing and light-curing mode. All samples were prepared by filling teflon ring-type molds. In addition, Vickers micro-hardness was measured for all samples. Maxcem Elite showed similar maximum strain values from 10% to 12% for both groups. Besides the maximum strain value, the 3 D-DIC method also enabled monitoring the change of strain field even after the recommended polymerization time. This method has shown that the polymerization shrinkage continues even after 10 min which disagreed with manufacturer's suggestion. Group II showed maximum strain values of 12% in the peripheral zone after 10 min, in the last Stage (Stage 60). Statistically significant difference was not found in the overall strain between self- and light-cured Maxcem Elite neither peripherally (p = 0.118) nor centrally (p = 0.879). However, statistical significance was found in strain regarding central and peripheral zone in both, self-cured (p = 0.020) and light-cured (p = 0.002) Maxcem Elite. The mean von Mises strain values in the periphery of the samples (Section 0) were significantly higher compared to strain values in the center of the samples (for Section 1 and 2). The last stage (Stage 60) of the light-cured Maxcem Elite polymerization showed significantly higher values of von Mises strain compared to initial stage (Stage 0). Higher values of micro-hardness were noticed on the surfaces directly exposed to LED lamp after performing measurements of micro-hardness on light-cured samples.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Journal of Adhesion Science & Technology",
title = "Analysis of the strain and hardness in self-cured and light-cured self-adhesive resin based cement",
pages = "2695-2684",
number = "24",
volume = "33",
doi = "10.1080/01694243.2019.1654221"
}

Mitrović, A., Tanasić, I., Mitrović, N., Miletić, V., Bakić, G., Milošević, M.,& Antonović, D.. (2019). Analysis of the strain and hardness in self-cured and light-cured self-adhesive resin based cement. in Journal of Adhesion Science & Technology
Taylor & Francis Ltd, Abingdon., 33(24), 2684-2695.
https://doi.org/10.1080/01694243.2019.1654221

Mitrović A, Tanasić I, Mitrović N, Miletić V, Bakić G, Milošević M, Antonović D. Analysis of the strain and hardness in self-cured and light-cured self-adhesive resin based cement. in Journal of Adhesion Science & Technology. 2019;33(24):2684-2695.
doi:10.1080/01694243.2019.1654221 .

Mitrović, Aleksandra, Tanasić, Ivan, Mitrović, Nenad, Miletić, Vesna, Bakić, Gordana, Milošević, Miloš, Antonović, Dušan, "Analysis of the strain and hardness in self-cured and light-cured self-adhesive resin based cement" in Journal of Adhesion Science & Technology, 33, no. 24 (2019):2684-2695,
https://doi.org/10.1080/01694243.2019.1654221 . .

TY  - JOUR
AU  - Stasić, Jovana
AU  - Selaković, Nenad
AU  - Puač, Nevena
AU  - Miletić, Maja
AU  - Malović, Gordana
AU  - Petrović, Zoran Lj
AU  - Veljović, Đorđe
AU  - Miletić, Vesna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4263
AB  - ObjectivesThe study aims to evaluate the effects of non-thermal atmospheric plasma (NTAP) treatments on dentin wetting and surface free energy (SFE) and compare the effects of NTAP treatment, etch-and-rinse, and self-etch protocols for application of universal adhesives.Materials and methodsMid-coronal dentin of intact third molars was used to measure contact angles of distilled water, ethylene-glycol, and diiodomethane and calculate SFE following different NTAP preset treatments (feeding gas consisting of pure He, He + 1% O-2, He + 1.5% O-2), power input (1 or 3W), and tip-to-surface distance (2, 4, or 8mm). Contact angles of reference liquids and SFE of dentin following He + 1.5% O-2 at 3-W and 4-mm treatment was compared to phosphoric acid etching. Contact angles of Single Bond Universal (SBU; 3M ESPE) and Clearfil Universal Bond (CUB; Kuraray Noritake) were measured following NTAP, etch-and-rinse, and self-etch protocols.ResultsNTAP significantly reduced contact angles of reference liquids and increased dentin SFE compared to untreated dentin (p lt 0.05). O-2 intensified the effect of He NTAP (p lt 0.05). NTAP and phosphoric acid increased dentin polarity and Lewis base surface characteristics. Phosphoric acid increased contact angles of adhesives compared to the self-etch protocol (p lt 0.05). NTAP resulted in lower adhesive contact angles than phosphoric acid, the difference being statistically significant for CUB (p lt 0.05). Compared to the self-etch protocol, NTAP slightly reduced CUB contact angle but not that of SBU (p gt 0.05).ConclusionsHe NTAP with and without O-2 increased dentin wetting and SFE, surpassing the effect of phosphoric acid and lowering adhesive contact angles. NTAP produced no apparent micro-morphological changes on dentin surface comparable to acid etching.Clinical significanceNTAP treatment of dentin prior to adhesive application increases dentin wetting and surface free energy facilitating better adhesive distribution on dentin surface compared to phosphoric acid etching and similar to the self-etch application protocol.
PB  - Springer Heidelberg, Heidelberg
T2  - Clinical Oral Investigations
T1  - Effects of non-thermal atmospheric plasma treatment on dentin wetting and surface free energy for application of universal adhesives
EP  - 1396
IS  - 3
SP  - 1383
VL  - 23
DO  - 10.1007/s00784-018-2563-2
ER  - 

@article{
author = "Stasić, Jovana and Selaković, Nenad and Puač, Nevena and Miletić, Maja and Malović, Gordana and Petrović, Zoran Lj and Veljović, Đorđe and Miletić, Vesna",
year = "2019",
abstract = "ObjectivesThe study aims to evaluate the effects of non-thermal atmospheric plasma (NTAP) treatments on dentin wetting and surface free energy (SFE) and compare the effects of NTAP treatment, etch-and-rinse, and self-etch protocols for application of universal adhesives.Materials and methodsMid-coronal dentin of intact third molars was used to measure contact angles of distilled water, ethylene-glycol, and diiodomethane and calculate SFE following different NTAP preset treatments (feeding gas consisting of pure He, He + 1% O-2, He + 1.5% O-2), power input (1 or 3W), and tip-to-surface distance (2, 4, or 8mm). Contact angles of reference liquids and SFE of dentin following He + 1.5% O-2 at 3-W and 4-mm treatment was compared to phosphoric acid etching. Contact angles of Single Bond Universal (SBU; 3M ESPE) and Clearfil Universal Bond (CUB; Kuraray Noritake) were measured following NTAP, etch-and-rinse, and self-etch protocols.ResultsNTAP significantly reduced contact angles of reference liquids and increased dentin SFE compared to untreated dentin (p lt 0.05). O-2 intensified the effect of He NTAP (p lt 0.05). NTAP and phosphoric acid increased dentin polarity and Lewis base surface characteristics. Phosphoric acid increased contact angles of adhesives compared to the self-etch protocol (p lt 0.05). NTAP resulted in lower adhesive contact angles than phosphoric acid, the difference being statistically significant for CUB (p lt 0.05). Compared to the self-etch protocol, NTAP slightly reduced CUB contact angle but not that of SBU (p gt 0.05).ConclusionsHe NTAP with and without O-2 increased dentin wetting and SFE, surpassing the effect of phosphoric acid and lowering adhesive contact angles. NTAP produced no apparent micro-morphological changes on dentin surface comparable to acid etching.Clinical significanceNTAP treatment of dentin prior to adhesive application increases dentin wetting and surface free energy facilitating better adhesive distribution on dentin surface compared to phosphoric acid etching and similar to the self-etch application protocol.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Clinical Oral Investigations",
title = "Effects of non-thermal atmospheric plasma treatment on dentin wetting and surface free energy for application of universal adhesives",
pages = "1396-1383",
number = "3",
volume = "23",
doi = "10.1007/s00784-018-2563-2"
}

Stasić, J., Selaković, N., Puač, N., Miletić, M., Malović, G., Petrović, Z. L., Veljović, Đ.,& Miletić, V.. (2019). Effects of non-thermal atmospheric plasma treatment on dentin wetting and surface free energy for application of universal adhesives. in Clinical Oral Investigations
Springer Heidelberg, Heidelberg., 23(3), 1383-1396.
https://doi.org/10.1007/s00784-018-2563-2

Stasić J, Selaković N, Puač N, Miletić M, Malović G, Petrović ZL, Veljović Đ, Miletić V. Effects of non-thermal atmospheric plasma treatment on dentin wetting and surface free energy for application of universal adhesives. in Clinical Oral Investigations. 2019;23(3):1383-1396.
doi:10.1007/s00784-018-2563-2 .

Stasić, Jovana, Selaković, Nenad, Puač, Nevena, Miletić, Maja, Malović, Gordana, Petrović, Zoran Lj, Veljović, Đorđe, Miletić, Vesna, "Effects of non-thermal atmospheric plasma treatment on dentin wetting and surface free energy for application of universal adhesives" in Clinical Oral Investigations, 23, no. 3 (2019):1383-1396,
https://doi.org/10.1007/s00784-018-2563-2 . .

TY  - JOUR
AU  - Miletić, Vesna
AU  - Marjanović, Jovana
AU  - Veljović, Đorđe
AU  - Stasić, Jovana
AU  - Petrović, Violeta
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4050
AB  - Objective To determine color changes in bulk-fill composite and universal composite restorations with dissimilar dentin replacement materials in extracted teeth after staining in red wine. Materials and Methods Cylindrical, 4 mm deep, class I cavities were prepared in 140 human molars. Bottom 2 mm was restored with Biodentine (Septodont), everX posterior (GC) or experimental HAP inserts. Each dentin replacement material was covered with a 2-mm layer of a universal composite Filtek Z250 or Z550 (3M ESPE) or Gradia Posterior (GC). Groups combining top composite layer and the underlying dentin replacement were designated as "composite_dentin replacement." Filtek Bulk Fill (3M ESPE) and Tetric EvoCeram Bulk Fill (Ivoclar Vivadent) were placed as a single 4-mm layer. Color measurements were performed using Vita Easyshade 4.0 (Vita Zahnfabrik) initially and after 48-hours storage in red wine at 37 degrees C. Results Color differences (Delta E-oo) ranged between 2.1 +/- 0.7 (Z250_HAP) and 7.8 +/- 1.1 (Z550_everX). EverX resulted in higher Delta E-oo of the overlying composite than HAP (P  lt  .001) and Biodentine (P = .006). Generally, Delta E-oo was affected more by decreasing lightness (Delta L ') than changes in chroma (Delta C '). Conclusions EverX resulted in higher Delta E-oo of the restoration than Biodentine and experimental HAP after staining in red wine. No significant differences in Delta E-oo may be expected in different composites with the same underlying dentin replacement material. The same was generally true for bulk-fill and universal composites. Clinical Significance Similar extent of color changes may be expected in bulk-fill and universal composites. Highly translucent everX might exhibit greater color differences irrespective of the capping composite than non-translucent materials. Clinicians have a wider choice of composite materials to cover a particular dentin replacement material, for example, everX or Biodentine, as similar color differences may be expected in various overlying composite brands.
PB  - Wiley, Hoboken
T2  - Journal of Esthetic and Restorative Dentistry
T1  - Color stability of bulk-fill and universal composite restorations with dissimilar dentin replacement materials
EP  - 528
IS  - 5
SP  - 520
VL  - 31
DO  - 10.1111/jerd.12529
ER  - 

@article{
author = "Miletić, Vesna and Marjanović, Jovana and Veljović, Đorđe and Stasić, Jovana and Petrović, Violeta",
year = "2019",
abstract = "Objective To determine color changes in bulk-fill composite and universal composite restorations with dissimilar dentin replacement materials in extracted teeth after staining in red wine. Materials and Methods Cylindrical, 4 mm deep, class I cavities were prepared in 140 human molars. Bottom 2 mm was restored with Biodentine (Septodont), everX posterior (GC) or experimental HAP inserts. Each dentin replacement material was covered with a 2-mm layer of a universal composite Filtek Z250 or Z550 (3M ESPE) or Gradia Posterior (GC). Groups combining top composite layer and the underlying dentin replacement were designated as "composite_dentin replacement." Filtek Bulk Fill (3M ESPE) and Tetric EvoCeram Bulk Fill (Ivoclar Vivadent) were placed as a single 4-mm layer. Color measurements were performed using Vita Easyshade 4.0 (Vita Zahnfabrik) initially and after 48-hours storage in red wine at 37 degrees C. Results Color differences (Delta E-oo) ranged between 2.1 +/- 0.7 (Z250_HAP) and 7.8 +/- 1.1 (Z550_everX). EverX resulted in higher Delta E-oo of the overlying composite than HAP (P  lt  .001) and Biodentine (P = .006). Generally, Delta E-oo was affected more by decreasing lightness (Delta L ') than changes in chroma (Delta C '). Conclusions EverX resulted in higher Delta E-oo of the restoration than Biodentine and experimental HAP after staining in red wine. No significant differences in Delta E-oo may be expected in different composites with the same underlying dentin replacement material. The same was generally true for bulk-fill and universal composites. Clinical Significance Similar extent of color changes may be expected in bulk-fill and universal composites. Highly translucent everX might exhibit greater color differences irrespective of the capping composite than non-translucent materials. Clinicians have a wider choice of composite materials to cover a particular dentin replacement material, for example, everX or Biodentine, as similar color differences may be expected in various overlying composite brands.",
publisher = "Wiley, Hoboken",
journal = "Journal of Esthetic and Restorative Dentistry",
title = "Color stability of bulk-fill and universal composite restorations with dissimilar dentin replacement materials",
pages = "528-520",
number = "5",
volume = "31",
doi = "10.1111/jerd.12529"
}

Miletić, V., Marjanović, J., Veljović, Đ., Stasić, J.,& Petrović, V.. (2019). Color stability of bulk-fill and universal composite restorations with dissimilar dentin replacement materials. in Journal of Esthetic and Restorative Dentistry
Wiley, Hoboken., 31(5), 520-528.
https://doi.org/10.1111/jerd.12529

Miletić V, Marjanović J, Veljović Đ, Stasić J, Petrović V. Color stability of bulk-fill and universal composite restorations with dissimilar dentin replacement materials. in Journal of Esthetic and Restorative Dentistry. 2019;31(5):520-528.
doi:10.1111/jerd.12529 .

Miletić, Vesna, Marjanović, Jovana, Veljović, Đorđe, Stasić, Jovana, Petrović, Violeta, "Color stability of bulk-fill and universal composite restorations with dissimilar dentin replacement materials" in Journal of Esthetic and Restorative Dentistry, 31, no. 5 (2019):520-528,
https://doi.org/10.1111/jerd.12529 . .

TY  - JOUR
AU  - Matić, Tamara
AU  - Ležaja-Zebić, Maja
AU  - Cvijović-Alagić, Ivana
AU  - Miletić, Vesna
AU  - Petrović, Rada
AU  - Janaćković, Đorđe
AU  - Veljović, Đorđe
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3918
AB  - This study aimed to investigate the possibility of modifying model BisGMA/TEGDMA dental composite by substituting 10 wt. % of conventional glass fillers with bioactive fillers based on calcinated nanosized hydroxyapatite (HAp) and Mg-doped hydroxyapatite (Mg-HAp). HAp and Mg-HAp powders were synthesized hydrothermally. Mechanical properties: hardness by Vickers (HV) and flexural strength (Fs) were tested initially and after being stored for 28 days in simulated body fluid (SBF). The experimental composites with HAp and Mg-HAp particles showed no statistically significant difference in HV compared to the control (p gt 0.05) either initially or after storage. Although mean Fs values of modified composites tested initially were lower (62 MPa) than those of the control (72 MPa), after 28 days of storage in SBF Fs values were greater for modified composites (42 MPa control sample, 48 MPa HAp, and Mg-HAp samples). In vitro bioactivity of BisGMA/TEGDMA composites with HAp and Mg-HAp particles after 28 days in SBF was not detected.
PB  - Savez inženjera metalurgije Srbije, Beograd
T2  - Metallurgical & Materials Engineering
T1  - The effect of calcinated hydroxyapatite and magnesium doped hydroxyapatite as fillers on the mechanical properties of a model bisgma/tegdma dental composite initially and after aging
EP  - 281
IS  - 4
SP  - 271
VL  - 24
DO  - 10.30544/403
ER  - 

@article{
author = "Matić, Tamara and Ležaja-Zebić, Maja and Cvijović-Alagić, Ivana and Miletić, Vesna and Petrović, Rada and Janaćković, Đorđe and Veljović, Đorđe",
year = "2018",
abstract = "This study aimed to investigate the possibility of modifying model BisGMA/TEGDMA dental composite by substituting 10 wt. % of conventional glass fillers with bioactive fillers based on calcinated nanosized hydroxyapatite (HAp) and Mg-doped hydroxyapatite (Mg-HAp). HAp and Mg-HAp powders were synthesized hydrothermally. Mechanical properties: hardness by Vickers (HV) and flexural strength (Fs) were tested initially and after being stored for 28 days in simulated body fluid (SBF). The experimental composites with HAp and Mg-HAp particles showed no statistically significant difference in HV compared to the control (p gt 0.05) either initially or after storage. Although mean Fs values of modified composites tested initially were lower (62 MPa) than those of the control (72 MPa), after 28 days of storage in SBF Fs values were greater for modified composites (42 MPa control sample, 48 MPa HAp, and Mg-HAp samples). In vitro bioactivity of BisGMA/TEGDMA composites with HAp and Mg-HAp particles after 28 days in SBF was not detected.",
publisher = "Savez inženjera metalurgije Srbije, Beograd",
journal = "Metallurgical & Materials Engineering",
title = "The effect of calcinated hydroxyapatite and magnesium doped hydroxyapatite as fillers on the mechanical properties of a model bisgma/tegdma dental composite initially and after aging",
pages = "281-271",
number = "4",
volume = "24",
doi = "10.30544/403"
}

Matić, T., Ležaja-Zebić, M., Cvijović-Alagić, I., Miletić, V., Petrović, R., Janaćković, Đ.,& Veljović, Đ.. (2018). The effect of calcinated hydroxyapatite and magnesium doped hydroxyapatite as fillers on the mechanical properties of a model bisgma/tegdma dental composite initially and after aging. in Metallurgical & Materials Engineering
Savez inženjera metalurgije Srbije, Beograd., 24(4), 271-281.
https://doi.org/10.30544/403

Matić T, Ležaja-Zebić M, Cvijović-Alagić I, Miletić V, Petrović R, Janaćković Đ, Veljović Đ. The effect of calcinated hydroxyapatite and magnesium doped hydroxyapatite as fillers on the mechanical properties of a model bisgma/tegdma dental composite initially and after aging. in Metallurgical & Materials Engineering. 2018;24(4):271-281.
doi:10.30544/403 .

Matić, Tamara, Ležaja-Zebić, Maja, Cvijović-Alagić, Ivana, Miletić, Vesna, Petrović, Rada, Janaćković, Đorđe, Veljović, Đorđe, "The effect of calcinated hydroxyapatite and magnesium doped hydroxyapatite as fillers on the mechanical properties of a model bisgma/tegdma dental composite initially and after aging" in Metallurgical & Materials Engineering, 24, no. 4 (2018):271-281,
https://doi.org/10.30544/403 . .

TY  - JOUR
AU  - Marjanović, Jovana
AU  - Veljović, Đorđe
AU  - Stasić, Jovana
AU  - Savić-Stanković, Tatjana
AU  - Trifković, Branka
AU  - Miletić, Vesna
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3999
AB  - Objectives. To evaluate optical properties (color and translucency) of 'sandwich' restorations of resin-based composites and esthetically unfavorable dentin restoratives. Methods. Cylindrical 'dentin' specimens (8 mm in diameter and 2 mm thick, N = 5/group) were prepared using EverX Posterior (GC), Biodentine (Septodont), experimental hydroxyapatite (HAP) or conventional composites (Gradia Direct Posterior, GC; Filtek Z250 and Filtek Z500, 3M ESPE). Capping 'enamel' layers were prepared using composites (Gradia Direct Posterior, Filtek Z250 or Z550) of Al or A3 shade and the following thickness: 0.6, 1 or 2 mm. Color (Delta E) and translucency parameter (TP) were determined using a spectrophotometer (VITA Easyshade Advance 4.0, VITA Zahnfabrik). Data were statistically analyzed using analysis of variance with Tukey's post-hoc tests (alpha = 0.05). Results. TP was greatly affected by layer thickness, whilst Delta E depended on shade and layer thickness of the capping composite. HAP and Biodentine showed significantly lower TP and higher Delta E (deviation from 'ideal white') than composites (p  lt  0.05). Greater TP was seen in EverX_composite groups than in corresponding control groups of the same shade and thickness. TP of composites combined with Biodentine or HAP was below 2, lower than the corresponding control groups (p  lt  0.05). Within-group differences of Delta E were greatest in HAP_composite groups. EverX_Gradia and EverX_FiltekZ250 combinations showed the most comparable Delta E with the control groups. Significance. A 2 mm thick layer of composite covering dentin restoratives with unfavorable esthetics is recommended for a final 'sandwich' restoration that is esthetically comparable to a conventional, mono-composite control restoration.
PB  - Elsevier Sci Ltd, Oxford
T2  - Dental Materials
T1  - Optical properties of composite restorations influenced by dissimilar dentin restoratives
EP  - 745
IS  - 5
SP  - 737
VL  - 34
DO  - 10.1016/j.dental.2018.01.017
ER  - 

@article{
author = "Marjanović, Jovana and Veljović, Đorđe and Stasić, Jovana and Savić-Stanković, Tatjana and Trifković, Branka and Miletić, Vesna",
year = "2018",
abstract = "Objectives. To evaluate optical properties (color and translucency) of 'sandwich' restorations of resin-based composites and esthetically unfavorable dentin restoratives. Methods. Cylindrical 'dentin' specimens (8 mm in diameter and 2 mm thick, N = 5/group) were prepared using EverX Posterior (GC), Biodentine (Septodont), experimental hydroxyapatite (HAP) or conventional composites (Gradia Direct Posterior, GC; Filtek Z250 and Filtek Z500, 3M ESPE). Capping 'enamel' layers were prepared using composites (Gradia Direct Posterior, Filtek Z250 or Z550) of Al or A3 shade and the following thickness: 0.6, 1 or 2 mm. Color (Delta E) and translucency parameter (TP) were determined using a spectrophotometer (VITA Easyshade Advance 4.0, VITA Zahnfabrik). Data were statistically analyzed using analysis of variance with Tukey's post-hoc tests (alpha = 0.05). Results. TP was greatly affected by layer thickness, whilst Delta E depended on shade and layer thickness of the capping composite. HAP and Biodentine showed significantly lower TP and higher Delta E (deviation from 'ideal white') than composites (p  lt  0.05). Greater TP was seen in EverX_composite groups than in corresponding control groups of the same shade and thickness. TP of composites combined with Biodentine or HAP was below 2, lower than the corresponding control groups (p  lt  0.05). Within-group differences of Delta E were greatest in HAP_composite groups. EverX_Gradia and EverX_FiltekZ250 combinations showed the most comparable Delta E with the control groups. Significance. A 2 mm thick layer of composite covering dentin restoratives with unfavorable esthetics is recommended for a final 'sandwich' restoration that is esthetically comparable to a conventional, mono-composite control restoration.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Dental Materials",
title = "Optical properties of composite restorations influenced by dissimilar dentin restoratives",
pages = "745-737",
number = "5",
volume = "34",
doi = "10.1016/j.dental.2018.01.017"
}

Marjanović, J., Veljović, Đ., Stasić, J., Savić-Stanković, T., Trifković, B.,& Miletić, V.. (2018). Optical properties of composite restorations influenced by dissimilar dentin restoratives. in Dental Materials
Elsevier Sci Ltd, Oxford., 34(5), 737-745.
https://doi.org/10.1016/j.dental.2018.01.017

Marjanović J, Veljović Đ, Stasić J, Savić-Stanković T, Trifković B, Miletić V. Optical properties of composite restorations influenced by dissimilar dentin restoratives. in Dental Materials. 2018;34(5):737-745.
doi:10.1016/j.dental.2018.01.017 .

Marjanović, Jovana, Veljović, Đorđe, Stasić, Jovana, Savić-Stanković, Tatjana, Trifković, Branka, Miletić, Vesna, "Optical properties of composite restorations influenced by dissimilar dentin restoratives" in Dental Materials, 34, no. 5 (2018):737-745,
https://doi.org/10.1016/j.dental.2018.01.017 . .

TY  - JOUR
AU  - Ayoub, Giuma
AU  - Veljović, Đorđe
AU  - Ležaja-Zebić, Maja
AU  - Miletić, Vesna
AU  - Palcevskis, Eriks
AU  - Petrović, Rada
AU  - Janaćković, Đorđe
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3936
AB  - The objective of the study was to process nano-structured hydroxyapatite/yttrium-stabilized zirconia bioceramic and to investigate the possibilities of its application as dentin replacement in the form of dental inserts. The processing conditions were varied in order to optimize phase composition, microstructure, fracture toughness, hardness and shear bond strength (SBS) between the obtained composite inserts and restorative materials, following either the "total-etch" or "self-etch" clinical protocol. Composite nano-powder, obtained by mixing and homogenization of 80 wt% of stoichiometric hydroxyapatite (HAp) synthesized by modified precipitation method and 20wt% of yttrium-stabilized ZrO2 (YSZ) synthesized by plasma method, was isostatically pressed into cylinder-shaped green bodies. After dilatometric analysis, HAp/YSZ inserts were sintered in the temperature range from 1200 degrees C to 1300 degrees C. Hardness and fracture toughness of sintered inserts were ranged between 3.90 +/- 0.20 - 3.95 +/- 0.12 GPa and 1.82 +/- 0.04 - 1.88 +/- 0.03 MPam(1/2), respectively. Microstructural analysis of biphasic HAp/t-ZrO2 inserts indicated two potential fracture mechanisms for fracture toughness increasing. Sintering temperature and different clinical protocols affected SBS between processed inserts and commercial dental restorative materials. Maximum SBS values of 10.50 +/- 4.94 MPa (mean standard deviation) were reached in inserts sintered at 1300 degrees C, following the "self-etch" protocol of adhesive application. It could be concluded that resin-based composites could be strongly bonded to HAp/YSZ inserts, preferably with self-etch" adhesive application. In addition, the values of fracture toughness and hardness of the obtained inserts indicated the possibility of their usage as dentin substitutes, which could be a good prerequisite for satisfactory mechanics of restored teeth.
PB  - Elsevier Sci Ltd, Oxford
T2  - Ceramics International
T1  - Composite nanostructured hydroxyapatite/yttrium stabilized zirconia dental inserts - The processing and application as dentin substitutes
EP  - 18208
IS  - 15
SP  - 18200
VL  - 44
DO  - 10.1016/j.ceramint.2018.07.028
ER  - 

@article{
author = "Ayoub, Giuma and Veljović, Đorđe and Ležaja-Zebić, Maja and Miletić, Vesna and Palcevskis, Eriks and Petrović, Rada and Janaćković, Đorđe",
year = "2018",
abstract = "The objective of the study was to process nano-structured hydroxyapatite/yttrium-stabilized zirconia bioceramic and to investigate the possibilities of its application as dentin replacement in the form of dental inserts. The processing conditions were varied in order to optimize phase composition, microstructure, fracture toughness, hardness and shear bond strength (SBS) between the obtained composite inserts and restorative materials, following either the "total-etch" or "self-etch" clinical protocol. Composite nano-powder, obtained by mixing and homogenization of 80 wt% of stoichiometric hydroxyapatite (HAp) synthesized by modified precipitation method and 20wt% of yttrium-stabilized ZrO2 (YSZ) synthesized by plasma method, was isostatically pressed into cylinder-shaped green bodies. After dilatometric analysis, HAp/YSZ inserts were sintered in the temperature range from 1200 degrees C to 1300 degrees C. Hardness and fracture toughness of sintered inserts were ranged between 3.90 +/- 0.20 - 3.95 +/- 0.12 GPa and 1.82 +/- 0.04 - 1.88 +/- 0.03 MPam(1/2), respectively. Microstructural analysis of biphasic HAp/t-ZrO2 inserts indicated two potential fracture mechanisms for fracture toughness increasing. Sintering temperature and different clinical protocols affected SBS between processed inserts and commercial dental restorative materials. Maximum SBS values of 10.50 +/- 4.94 MPa (mean standard deviation) were reached in inserts sintered at 1300 degrees C, following the "self-etch" protocol of adhesive application. It could be concluded that resin-based composites could be strongly bonded to HAp/YSZ inserts, preferably with self-etch" adhesive application. In addition, the values of fracture toughness and hardness of the obtained inserts indicated the possibility of their usage as dentin substitutes, which could be a good prerequisite for satisfactory mechanics of restored teeth.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Ceramics International",
title = "Composite nanostructured hydroxyapatite/yttrium stabilized zirconia dental inserts - The processing and application as dentin substitutes",
pages = "18208-18200",
number = "15",
volume = "44",
doi = "10.1016/j.ceramint.2018.07.028"
}

Ayoub, G., Veljović, Đ., Ležaja-Zebić, M., Miletić, V., Palcevskis, E., Petrović, R.,& Janaćković, Đ.. (2018). Composite nanostructured hydroxyapatite/yttrium stabilized zirconia dental inserts - The processing and application as dentin substitutes. in Ceramics International
Elsevier Sci Ltd, Oxford., 44(15), 18200-18208.
https://doi.org/10.1016/j.ceramint.2018.07.028

Ayoub G, Veljović Đ, Ležaja-Zebić M, Miletić V, Palcevskis E, Petrović R, Janaćković Đ. Composite nanostructured hydroxyapatite/yttrium stabilized zirconia dental inserts - The processing and application as dentin substitutes. in Ceramics International. 2018;44(15):18200-18208.
doi:10.1016/j.ceramint.2018.07.028 .

Ayoub, Giuma, Veljović, Đorđe, Ležaja-Zebić, Maja, Miletić, Vesna, Palcevskis, Eriks, Petrović, Rada, Janaćković, Đorđe, "Composite nanostructured hydroxyapatite/yttrium stabilized zirconia dental inserts - The processing and application as dentin substitutes" in Ceramics International, 44, no. 15 (2018):18200-18208,
https://doi.org/10.1016/j.ceramint.2018.07.028 . .

TY  - JOUR
AU  - Ležaja, Maja
AU  - Jokić, Bojan
AU  - Veljović, Đorđe
AU  - Miletić, Vesna
PY  - 2016
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3276
AB  - The aim of this study was to compare the effect of hydroxyapatite (HAP) nano-rods (HAP rods) and HAP nano-sticks (HAP sticks) added to commercial adhesives on the macro-shear bond strength (SBS) to dentine and morphology of the adhesive-dentine interface. HAP was added to Single Bond Universal (SBU, 3M ESPE) and Te-Econom Bond (TeE; Ivoclar Vivadent), in the form of water suspensions to avoid agglomeration of nano-particles and to achieve HAP concentrations of 0.5, 1.0 and 1.5 wt%. Following a 'total-etch' or a 'self-etch' protocol, the adhesives were applied to flat dentine surface of 162 intact human, third molars (N = 6/group). Composite (Z250, 3M ESPE) was built-up using a split stainless steel mould, 3 mm in diameter. SBS was tested using a universal testing machine at 1 mm/min until fracture. Data were statistically analysed using two-way and one-way analysis of variance with Tukey's post-test (alpha = 0.05). HAP(rods) had no significant effect on SBS of the tested adhesives while HAP(sticks) improved bond strength to dentine only of adhesives applied following the 'total-etch' total-etch protocol. SBS values of SBU containing 1% HAP(sticks) (15.10 +/- 2.96 MPa) and TeE containing 0.5% HAP(sticks) applied following the total-etch protocol (12.96 +/- 4.48 MPa) were higher than those of their respective control groups (10.36 +/- 2.68 and 7.97 +/- 3.64 MPa). Samples with higher SBS showed more 'mixed' failures. HAP nano-fillers may improve bond strength of total-etch adhesives without an adverse effect on adhesive dispersion on dentine and its ability to infiltrate dentinal tubules.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Journal of Adhesion Science and Technology
T1  - Shear bond strength to dentine of dental adhesives containing hydroxyapatite nano-fillers
EP  - 2689
IS  - 24
SP  - 2678
VL  - 30
DO  - 10.1080/01694243.2016.1197086
ER  - 

@article{
author = "Ležaja, Maja and Jokić, Bojan and Veljović, Đorđe and Miletić, Vesna",
year = "2016",
abstract = "The aim of this study was to compare the effect of hydroxyapatite (HAP) nano-rods (HAP rods) and HAP nano-sticks (HAP sticks) added to commercial adhesives on the macro-shear bond strength (SBS) to dentine and morphology of the adhesive-dentine interface. HAP was added to Single Bond Universal (SBU, 3M ESPE) and Te-Econom Bond (TeE; Ivoclar Vivadent), in the form of water suspensions to avoid agglomeration of nano-particles and to achieve HAP concentrations of 0.5, 1.0 and 1.5 wt%. Following a 'total-etch' or a 'self-etch' protocol, the adhesives were applied to flat dentine surface of 162 intact human, third molars (N = 6/group). Composite (Z250, 3M ESPE) was built-up using a split stainless steel mould, 3 mm in diameter. SBS was tested using a universal testing machine at 1 mm/min until fracture. Data were statistically analysed using two-way and one-way analysis of variance with Tukey's post-test (alpha = 0.05). HAP(rods) had no significant effect on SBS of the tested adhesives while HAP(sticks) improved bond strength to dentine only of adhesives applied following the 'total-etch' total-etch protocol. SBS values of SBU containing 1% HAP(sticks) (15.10 +/- 2.96 MPa) and TeE containing 0.5% HAP(sticks) applied following the total-etch protocol (12.96 +/- 4.48 MPa) were higher than those of their respective control groups (10.36 +/- 2.68 and 7.97 +/- 3.64 MPa). Samples with higher SBS showed more 'mixed' failures. HAP nano-fillers may improve bond strength of total-etch adhesives without an adverse effect on adhesive dispersion on dentine and its ability to infiltrate dentinal tubules.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Journal of Adhesion Science and Technology",
title = "Shear bond strength to dentine of dental adhesives containing hydroxyapatite nano-fillers",
pages = "2689-2678",
number = "24",
volume = "30",
doi = "10.1080/01694243.2016.1197086"
}

Ležaja, M., Jokić, B., Veljović, Đ.,& Miletić, V.. (2016). Shear bond strength to dentine of dental adhesives containing hydroxyapatite nano-fillers. in Journal of Adhesion Science and Technology
Taylor & Francis Ltd, Abingdon., 30(24), 2678-2689.
https://doi.org/10.1080/01694243.2016.1197086

Ležaja M, Jokić B, Veljović Đ, Miletić V. Shear bond strength to dentine of dental adhesives containing hydroxyapatite nano-fillers. in Journal of Adhesion Science and Technology. 2016;30(24):2678-2689.
doi:10.1080/01694243.2016.1197086 .

Ležaja, Maja, Jokić, Bojan, Veljović, Đorđe, Miletić, Vesna, "Shear bond strength to dentine of dental adhesives containing hydroxyapatite nano-fillers" in Journal of Adhesion Science and Technology, 30, no. 24 (2016):2678-2689,
https://doi.org/10.1080/01694243.2016.1197086 . .

TY  - JOUR
AU  - Ležaja, Maja
AU  - Veljović, Đorđe
AU  - Manojlović, Dragica
AU  - Milošević, Miloš
AU  - Mitrović, Nenad
AU  - Janaćković, Đorđe
AU  - Miletić, Vesna
PY  - 2015
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3036
AB  - Objective. To determine the shear bond strength (SBS) between synthetic controlled porous hydroxyapatite (HAP) inserts and restorative materials and dimensional changes of insert-containing restorations during curing. Methods. Cylinder-shaped HAP inserts (4 mm in diameter, 1.6 mm thick) were cemented in dentin discs (5 mm x 1.6 mm), cut mid-coronally from human third molars, using one of the following materials: universal microhybrid composite Filtek Z250, flowable composite Filtek Ultimate or glass-ionomer Vitrebond (all 3M ESPE). SBS of the same materials to HAP inserts was tested in a universal testing machine. Three-dimensional digital image correlation system Aramis (GOM) was used to measure strains and displacements. Data were statistically analyzed using one-way ANOVA with Tukey's post-test (alpha = 0.05). Results. SBS of restorative materials to HAP inserts ranged between 12.2 +/- 2.1 MPa (Filtek Z250) and 0.7 +/- 0.4 MPa (Filtek Z250 without an adhesive). The 'total-etch' approach of adhesive application significantly increased SBS of both Filtek Z250 (12.2 +/- 2.1 MPa) and Filtek Ultimate flowable (9.5 +/- 2.5 MPa) compared to the 'self-etch' approach (8.2 +/- 1.6 MPa and 4.4 +/- 0.9 MPa, respectively) (p  lt  0.05). HAP inserts reduced polymerization shrinkage to below 0.5% as well as displacements in the central region of the restorations. Peripheral shrinkage of restorative materials was similar with and without HAP inserts as were displacements of Filtek Z250 and Vitrebond. Significance. Replacing major part of dentin clinically, especially in large cavities, HAP inserts may shorten clinical working time, improve dimensional stability of the restoration by reducing central shrinkage and displacements and provide adhesive bonding to universal composites following a 'total-etch' approach.
PB  - Elsevier Sci Ltd, Oxford
T2  - Dental Materials
T1  - Bond strength of restorative materials to hydroxyapatite inserts and dimensional changes of insert-containing restorations during polymerization
EP  - 181
IS  - 2
SP  - 171
VL  - 31
DO  - 10.1016/j.dental.2014.11.017
ER  - 

@article{
author = "Ležaja, Maja and Veljović, Đorđe and Manojlović, Dragica and Milošević, Miloš and Mitrović, Nenad and Janaćković, Đorđe and Miletić, Vesna",
year = "2015",
abstract = "Objective. To determine the shear bond strength (SBS) between synthetic controlled porous hydroxyapatite (HAP) inserts and restorative materials and dimensional changes of insert-containing restorations during curing. Methods. Cylinder-shaped HAP inserts (4 mm in diameter, 1.6 mm thick) were cemented in dentin discs (5 mm x 1.6 mm), cut mid-coronally from human third molars, using one of the following materials: universal microhybrid composite Filtek Z250, flowable composite Filtek Ultimate or glass-ionomer Vitrebond (all 3M ESPE). SBS of the same materials to HAP inserts was tested in a universal testing machine. Three-dimensional digital image correlation system Aramis (GOM) was used to measure strains and displacements. Data were statistically analyzed using one-way ANOVA with Tukey's post-test (alpha = 0.05). Results. SBS of restorative materials to HAP inserts ranged between 12.2 +/- 2.1 MPa (Filtek Z250) and 0.7 +/- 0.4 MPa (Filtek Z250 without an adhesive). The 'total-etch' approach of adhesive application significantly increased SBS of both Filtek Z250 (12.2 +/- 2.1 MPa) and Filtek Ultimate flowable (9.5 +/- 2.5 MPa) compared to the 'self-etch' approach (8.2 +/- 1.6 MPa and 4.4 +/- 0.9 MPa, respectively) (p  lt  0.05). HAP inserts reduced polymerization shrinkage to below 0.5% as well as displacements in the central region of the restorations. Peripheral shrinkage of restorative materials was similar with and without HAP inserts as were displacements of Filtek Z250 and Vitrebond. Significance. Replacing major part of dentin clinically, especially in large cavities, HAP inserts may shorten clinical working time, improve dimensional stability of the restoration by reducing central shrinkage and displacements and provide adhesive bonding to universal composites following a 'total-etch' approach.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Dental Materials",
title = "Bond strength of restorative materials to hydroxyapatite inserts and dimensional changes of insert-containing restorations during polymerization",
pages = "181-171",
number = "2",
volume = "31",
doi = "10.1016/j.dental.2014.11.017"
}

Ležaja, M., Veljović, Đ., Manojlović, D., Milošević, M., Mitrović, N., Janaćković, Đ.,& Miletić, V.. (2015). Bond strength of restorative materials to hydroxyapatite inserts and dimensional changes of insert-containing restorations during polymerization. in Dental Materials
Elsevier Sci Ltd, Oxford., 31(2), 171-181.
https://doi.org/10.1016/j.dental.2014.11.017

Ležaja M, Veljović Đ, Manojlović D, Milošević M, Mitrović N, Janaćković Đ, Miletić V. Bond strength of restorative materials to hydroxyapatite inserts and dimensional changes of insert-containing restorations during polymerization. in Dental Materials. 2015;31(2):171-181.
doi:10.1016/j.dental.2014.11.017 .

Ležaja, Maja, Veljović, Đorđe, Manojlović, Dragica, Milošević, Miloš, Mitrović, Nenad, Janaćković, Đorđe, Miletić, Vesna, "Bond strength of restorative materials to hydroxyapatite inserts and dimensional changes of insert-containing restorations during polymerization" in Dental Materials, 31, no. 2 (2015):171-181,
https://doi.org/10.1016/j.dental.2014.11.017 . .

TY  - JOUR
AU  - Manojlović, Dragica
AU  - Radisić, Marina
AU  - Laušević, Mila
AU  - Živković, Slavoljub
AU  - Miletić, Vesna
PY  - 2013
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5704
AB  - Elution of potentially toxic substances, including monomers, from resin-based dental composites may affect the biocompatibility of these materials in clinical conditions. In addition to the amounts of eluted monomers, mathematical modeling of elution kinetics reveals composite restorations as potential chronic sources of leachable monomers. The aim of this work was to experimentally quantify elution of main cross-linking monomers from four commercial composites and offer a mathematical model of elution kinetics. Composite samples (n = 7 per group) of Filtek Supreme XT (3M ESPE), Tetric EvoCeram (Ivoclar Vivadent), Admira (Voco), and Filtek Z250 (3M ESPE) were prepared in 2-mm thick Teflon moulds and cured with halogen or light-emitting diode light. Monomer elution in ethanol and water was analyzed using high-performance liquid chromatography up to 28 days postimmersion. The mathematical model was expressed as a sum of two exponential regression functions representing the first-order kinetics law. Elution kinetics in all cases followed the same mathematical model though differences in rate constants as well as the extent of monomer elution were material-, LCU-, medium-dependent. The proposed mechanisms of elution indicate fast elution from surface and subsurface layers and up to 100 times slower monomer extraction from the bulk polymer.
PB  - Wiley-Blackwell, Hoboken
T2  - Journal of Biomedical Materials Research Part B: Applied Biomaterials
T1  - Mathematical modeling of cross-linking monomer elution from resin-based dental composites
EP  - 67
IS  - 1
SP  - 61
VL  - 101B
DO  - 10.1002/jbm.b.32815
ER  - 

@article{
author = "Manojlović, Dragica and Radisić, Marina and Laušević, Mila and Živković, Slavoljub and Miletić, Vesna",
year = "2013",
abstract = "Elution of potentially toxic substances, including monomers, from resin-based dental composites may affect the biocompatibility of these materials in clinical conditions. In addition to the amounts of eluted monomers, mathematical modeling of elution kinetics reveals composite restorations as potential chronic sources of leachable monomers. The aim of this work was to experimentally quantify elution of main cross-linking monomers from four commercial composites and offer a mathematical model of elution kinetics. Composite samples (n = 7 per group) of Filtek Supreme XT (3M ESPE), Tetric EvoCeram (Ivoclar Vivadent), Admira (Voco), and Filtek Z250 (3M ESPE) were prepared in 2-mm thick Teflon moulds and cured with halogen or light-emitting diode light. Monomer elution in ethanol and water was analyzed using high-performance liquid chromatography up to 28 days postimmersion. The mathematical model was expressed as a sum of two exponential regression functions representing the first-order kinetics law. Elution kinetics in all cases followed the same mathematical model though differences in rate constants as well as the extent of monomer elution were material-, LCU-, medium-dependent. The proposed mechanisms of elution indicate fast elution from surface and subsurface layers and up to 100 times slower monomer extraction from the bulk polymer.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Journal of Biomedical Materials Research Part B: Applied Biomaterials",
title = "Mathematical modeling of cross-linking monomer elution from resin-based dental composites",
pages = "67-61",
number = "1",
volume = "101B",
doi = "10.1002/jbm.b.32815"
}

Manojlović, D., Radisić, M., Laušević, M., Živković, S.,& Miletić, V.. (2013). Mathematical modeling of cross-linking monomer elution from resin-based dental composites. in Journal of Biomedical Materials Research Part B: Applied Biomaterials
Wiley-Blackwell, Hoboken., 101B(1), 61-67.
https://doi.org/10.1002/jbm.b.32815

Manojlović D, Radisić M, Laušević M, Živković S, Miletić V. Mathematical modeling of cross-linking monomer elution from resin-based dental composites. in Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2013;101B(1):61-67.
doi:10.1002/jbm.b.32815 .

Manojlović, Dragica, Radisić, Marina, Laušević, Mila, Živković, Slavoljub, Miletić, Vesna, "Mathematical modeling of cross-linking monomer elution from resin-based dental composites" in Journal of Biomedical Materials Research Part B: Applied Biomaterials, 101B, no. 1 (2013):61-67,
https://doi.org/10.1002/jbm.b.32815 . .

TY  - JOUR
AU  - Lezaja, Maja
AU  - Veljović, Đorđe
AU  - Jokić, Bojan
AU  - Cvijović-Alagić, Ivana
AU  - Zrilić, Milorad
AU  - Miletić, Vesna
PY  - 2013
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2471
AB  - This study investigated the effect of shape, size, and surface modification of hydroxyapatite (HAP) fillers on the degree of conversion (DC) and mechanical properties of a model BisGMA/TEGDMA composite initially and after 4 weeks of storage. Ten percent of conventional glass fillers were replaced by HAP spheres (Sph), silicon-doped spheres (Sph(Si)), whiskers (Wh), silicon-doped whiskers (Wh(Si)), and nanosized HAP particles (Nano). Spheres were specifically structured agglomerates consisting of a central void and radially orientated primary particles, whereas whiskers were compact monocrystals. DC, Vickers hardness (HV), flexural strength (Fs), flexural modulus (Ef), compressive strength (Cs), and compressive modulus (Ec) were tested. There were no significant differences in the DC between all tested groups. HV decreased by 5.4-17% with the addition of HAP, while Fs increased by 13.9-29% except in Nano group (decrease by 13%). After storage, Sph and Sph(Si) groups showed similar HV, Ef, Cs and Ec and higher Fs than the control. The fracture mode of HAP spheres was through the central void whereas whiskers showed longitudinal delamination, transverse, and mixed fractures. HAP spheres with or without silicon- doping have a potential to be part of the filler content of dental composites.
PB  - Wiley-Blackwell, Hoboken
T2  - Journal of Biomedical Materials Research Part B-Applied Biomaterials
T1  - Effect of hydroxyapatite spheres, whiskers, and nanoparticles on mechanical properties of a model BisGMA/TEGDMA composite initially and after storage
EP  - 1476
IS  - 8
SP  - 1469
VL  - 101
DO  - 10.1002/jbm.b.32967
ER  - 

@article{
author = "Lezaja, Maja and Veljović, Đorđe and Jokić, Bojan and Cvijović-Alagić, Ivana and Zrilić, Milorad and Miletić, Vesna",
year = "2013",
abstract = "This study investigated the effect of shape, size, and surface modification of hydroxyapatite (HAP) fillers on the degree of conversion (DC) and mechanical properties of a model BisGMA/TEGDMA composite initially and after 4 weeks of storage. Ten percent of conventional glass fillers were replaced by HAP spheres (Sph), silicon-doped spheres (Sph(Si)), whiskers (Wh), silicon-doped whiskers (Wh(Si)), and nanosized HAP particles (Nano). Spheres were specifically structured agglomerates consisting of a central void and radially orientated primary particles, whereas whiskers were compact monocrystals. DC, Vickers hardness (HV), flexural strength (Fs), flexural modulus (Ef), compressive strength (Cs), and compressive modulus (Ec) were tested. There were no significant differences in the DC between all tested groups. HV decreased by 5.4-17% with the addition of HAP, while Fs increased by 13.9-29% except in Nano group (decrease by 13%). After storage, Sph and Sph(Si) groups showed similar HV, Ef, Cs and Ec and higher Fs than the control. The fracture mode of HAP spheres was through the central void whereas whiskers showed longitudinal delamination, transverse, and mixed fractures. HAP spheres with or without silicon- doping have a potential to be part of the filler content of dental composites.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Journal of Biomedical Materials Research Part B-Applied Biomaterials",
title = "Effect of hydroxyapatite spheres, whiskers, and nanoparticles on mechanical properties of a model BisGMA/TEGDMA composite initially and after storage",
pages = "1476-1469",
number = "8",
volume = "101",
doi = "10.1002/jbm.b.32967"
}

Lezaja, M., Veljović, Đ., Jokić, B., Cvijović-Alagić, I., Zrilić, M.,& Miletić, V.. (2013). Effect of hydroxyapatite spheres, whiskers, and nanoparticles on mechanical properties of a model BisGMA/TEGDMA composite initially and after storage. in Journal of Biomedical Materials Research Part B-Applied Biomaterials
Wiley-Blackwell, Hoboken., 101(8), 1469-1476.
https://doi.org/10.1002/jbm.b.32967

Lezaja M, Veljović Đ, Jokić B, Cvijović-Alagić I, Zrilić M, Miletić V. Effect of hydroxyapatite spheres, whiskers, and nanoparticles on mechanical properties of a model BisGMA/TEGDMA composite initially and after storage. in Journal of Biomedical Materials Research Part B-Applied Biomaterials. 2013;101(8):1469-1476.
doi:10.1002/jbm.b.32967 .

Lezaja, Maja, Veljović, Đorđe, Jokić, Bojan, Cvijović-Alagić, Ivana, Zrilić, Milorad, Miletić, Vesna, "Effect of hydroxyapatite spheres, whiskers, and nanoparticles on mechanical properties of a model BisGMA/TEGDMA composite initially and after storage" in Journal of Biomedical Materials Research Part B-Applied Biomaterials, 101, no. 8 (2013):1469-1476,
https://doi.org/10.1002/jbm.b.32967 . .

TY  - JOUR
AU  - Manojlović, Dragica
AU  - Radisić, Marina
AU  - Vasiljević, Tatjana
AU  - Živković, Slavoljub
AU  - Laušević, Mila
AU  - Miletić, Vesna
PY  - 2011
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5640
AB  - Objectives. To study monomer elution from four resin-based composites (RBCs) cured with different light sources. Methods. Twenty-eight premolars were randomly allocated to four groups. Standardized cavities were prepared and restored with a nanohybrid (Filtek Supreme XT or Tetric EvoCeram), an ormocer (Admira) or a microhybrid RBC (Filtek Z250) which served as control. Buccal restorations were cured with a halogen and oral restorations with an LED light-curing unit. Elution of diurethane dimethacrylate (UDMA), Bisphenol A diglycidylether methacrylate (BisGMA), triethylene glycol dimethacrylate (TEGDMA) and 2-hydroxyethyl methacrylate (HEMA) was analyzed using high-performance liquid chromatography (HPLC) 1h to 28 days post-immersion in 75% ethanol. Data were analyzed using multivariate and repeated measures analysis of variance (alpha = 0.05). Results. The greatest elution of UDMA and BisGMA occurred from Tetric EvoCeram and the least from Filtek Z250 (p  lt  0.05). LED and halogen light-curing units gave similar results for all RBCs (p > 0.05) except Tetric EvoCeram which showed greater elution for the LED unit (p  lt  0.05). TEGDMA was below the limit of quantification. HEMA eluted in similar concentrations from Filtek Supreme and Tetric EvoCeram (p > 0.05). Significance. : The two nanohybrid RBCs eluted more cross-linking monomers than the ormocer and the control microhybrid RBC. Continuous elution over 28 days indicates that RBCs act as a chronic source of monomers in clinical conditions. Light source may affect monomer elution since differences were found for one out of four RBCs. Mathematical models for elution kinetics of UDMA and BisGMA indicated two elution mechanisms.
PB  - Elsevier Sci Ltd, Oxford
T2  - Dental Materials
T1  - Monomer elution from nanohybrid and ormocer-based composites cured with different light sources
EP  - 378
IS  - 4
SP  - 371
VL  - 27
DO  - 10.1016/j.dental.2010.11.017
ER  - 

@article{
author = "Manojlović, Dragica and Radisić, Marina and Vasiljević, Tatjana and Živković, Slavoljub and Laušević, Mila and Miletić, Vesna",
year = "2011",
abstract = "Objectives. To study monomer elution from four resin-based composites (RBCs) cured with different light sources. Methods. Twenty-eight premolars were randomly allocated to four groups. Standardized cavities were prepared and restored with a nanohybrid (Filtek Supreme XT or Tetric EvoCeram), an ormocer (Admira) or a microhybrid RBC (Filtek Z250) which served as control. Buccal restorations were cured with a halogen and oral restorations with an LED light-curing unit. Elution of diurethane dimethacrylate (UDMA), Bisphenol A diglycidylether methacrylate (BisGMA), triethylene glycol dimethacrylate (TEGDMA) and 2-hydroxyethyl methacrylate (HEMA) was analyzed using high-performance liquid chromatography (HPLC) 1h to 28 days post-immersion in 75% ethanol. Data were analyzed using multivariate and repeated measures analysis of variance (alpha = 0.05). Results. The greatest elution of UDMA and BisGMA occurred from Tetric EvoCeram and the least from Filtek Z250 (p  lt  0.05). LED and halogen light-curing units gave similar results for all RBCs (p > 0.05) except Tetric EvoCeram which showed greater elution for the LED unit (p  lt  0.05). TEGDMA was below the limit of quantification. HEMA eluted in similar concentrations from Filtek Supreme and Tetric EvoCeram (p > 0.05). Significance. : The two nanohybrid RBCs eluted more cross-linking monomers than the ormocer and the control microhybrid RBC. Continuous elution over 28 days indicates that RBCs act as a chronic source of monomers in clinical conditions. Light source may affect monomer elution since differences were found for one out of four RBCs. Mathematical models for elution kinetics of UDMA and BisGMA indicated two elution mechanisms.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Dental Materials",
title = "Monomer elution from nanohybrid and ormocer-based composites cured with different light sources",
pages = "378-371",
number = "4",
volume = "27",
doi = "10.1016/j.dental.2010.11.017"
}

Manojlović, D., Radisić, M., Vasiljević, T., Živković, S., Laušević, M.,& Miletić, V.. (2011). Monomer elution from nanohybrid and ormocer-based composites cured with different light sources. in Dental Materials
Elsevier Sci Ltd, Oxford., 27(4), 371-378.
https://doi.org/10.1016/j.dental.2010.11.017

Manojlović D, Radisić M, Vasiljević T, Živković S, Laušević M, Miletić V. Monomer elution from nanohybrid and ormocer-based composites cured with different light sources. in Dental Materials. 2011;27(4):371-378.
doi:10.1016/j.dental.2010.11.017 .

Manojlović, Dragica, Radisić, Marina, Vasiljević, Tatjana, Živković, Slavoljub, Laušević, Mila, Miletić, Vesna, "Monomer elution from nanohybrid and ormocer-based composites cured with different light sources" in Dental Materials, 27, no. 4 (2011):371-378,
https://doi.org/10.1016/j.dental.2010.11.017 . .