Prikaz osnovnih podataka o dokumentu
Poly[(N-isopropylacrylamide)-co-(itaconic acid)] hydrogels with poly(ethylene glycol)
dc.creator | Kalagasidis Krušić, Melina | |
dc.creator | Veličković, Sava | |
dc.creator | Griffiths, Peter C. | |
dc.creator | Filipović, Jovanka | |
dc.date.accessioned | 2021-03-10T11:21:54Z | |
dc.date.available | 2021-03-10T11:21:54Z | |
dc.date.issued | 2010 | |
dc.identifier.issn | 0959-8103 | |
dc.identifier.uri | http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1682 | |
dc.description.abstract | The aim of the work reported here was to investigate temperature- and pH-sensitive hydrogels of N-isopropylacrylamide (NIPAM) and itaconic acid (IA) and their semi-interpenetrating polymer networks (semi-IPNs) with varying contents of poly(ethylene glycol) (PEG). The stimuli responsiveness, swelling behaviour and mechanical properties of the hydrogels and semi-IPNs were studied in order to investigate the effect of various amounts of PEG. Pulsed-gradient spin-echo NMR experiments were carried out to investigate the diffusion process. The pH sensitivity increased with an increasing amount of PEG in the semi-IPNs, while the overall rate of water uptake was diffusion-controlled (n lt 0.5). For certain PEG contents (5 and 10 wt%), the semi-IPNs exhibited better mechanical properties than the poly(NIPAM-co-IA) copolymer. The calculated values of the self-diffusion coefficients of water indicated facilitated diffusion of water through the system with increased amounts of PEG, while the self-diffusion coefficients of a model compound, metoprolol tartrate, showed no significant dependence on the amount of PEG. According to the results obtained and compared to results reported in the literature, the investigated semi-IPNs may have potential applications in the controlled release of macromolecular active agents such as proteins and peptides. | en |
dc.publisher | Wiley, Hoboken | |
dc.relation | info:eu-repo/grantAgreement/MESTD/MPN2006-2010/142023/RS// | |
dc.rights | restrictedAccess | |
dc.source | Polymer International | |
dc.subject | hydrogels | en |
dc.subject | semi-IPNs | en |
dc.subject | mechanical properties | en |
dc.subject | diffusion | en |
dc.title | Poly[(N-isopropylacrylamide)-co-(itaconic acid)] hydrogels with poly(ethylene glycol) | en |
dc.type | article | |
dc.rights.license | ARR | |
dc.citation.epage | 262 | |
dc.citation.issue | 2 | |
dc.citation.other | 59(2): 256-262 | |
dc.citation.rank | M21 | |
dc.citation.spage | 256 | |
dc.citation.volume | 59 | |
dc.identifier.doi | 10.1002/pi.2717 | |
dc.identifier.scopus | 2-s2.0-77953343291 | |
dc.identifier.wos | 000273922300017 | |
dc.type.version | publishedVersion |