TY  - JOUR
AU  - Taboun, Abdulrraouf
AU  - Jovanović, Marija
AU  - Petrović, Miloš
AU  - Stajčić, Ivana
AU  - Pešić, Ivan
AU  - Stojanović, Dušica B.
AU  - Radojević, Vesna
PY  - 2024
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7455
AB  - The aim of this study is to investigate the influence of cross-linking and reinforcements in gelatin on the physico-mechanical properties of obtained composites. The gelatin-based composites cross-linked with citric acid (CA) were prepared: gelatin type B (GB) and β-tricalcium phosphate (β-TCP) and novel hybrid composite GB with β-TCP and hydroxyapatite (HAp) particles, and their structure, thermal, and mechanical properties were compared with pure gelatin B samples. FTIR analysis revealed that no chemical interaction between the reinforcements and gelatin matrix was established during the processing of hybrid composites by the solution casting method, proving the particles had no influence on GB cross-linking. The morphological investigation of hybrid composites revealed that cross-linking with CA improved the dispersion of particles, which further led to an increase in mechanical performance. The microindentation test showed that the hardness value was increased by up to 449%, which shows the high potential of β-TCP and HAp particle reinforcement combined with CA as a cross-linking agent. Furthermore, the reduced modulus of elasticity was increased by up to 288%. Results of the MTT assay on L929 cells have revealed that the hybrid composite GB-TCP-HA-CA was not cytotoxic. These results showed that GB cross-linked with CA and reinforced with different calcium phosphates presents a valuable novel material with potential applications in dentistry.
PB  - MDPI
T2  - Polymers
T1  - Citric Acid Cross-Linked Gelatin-Based Composites with Improved Microhardness
IS  - 8
SP  - 1077
VL  - 16
DO  - 10.3390/polym16081077
ER  - 

@article{
author = "Taboun, Abdulrraouf and Jovanović, Marija and Petrović, Miloš and Stajčić, Ivana and Pešić, Ivan and Stojanović, Dušica B. and Radojević, Vesna",
year = "2024",
abstract = "The aim of this study is to investigate the influence of cross-linking and reinforcements in gelatin on the physico-mechanical properties of obtained composites. The gelatin-based composites cross-linked with citric acid (CA) were prepared: gelatin type B (GB) and β-tricalcium phosphate (β-TCP) and novel hybrid composite GB with β-TCP and hydroxyapatite (HAp) particles, and their structure, thermal, and mechanical properties were compared with pure gelatin B samples. FTIR analysis revealed that no chemical interaction between the reinforcements and gelatin matrix was established during the processing of hybrid composites by the solution casting method, proving the particles had no influence on GB cross-linking. The morphological investigation of hybrid composites revealed that cross-linking with CA improved the dispersion of particles, which further led to an increase in mechanical performance. The microindentation test showed that the hardness value was increased by up to 449%, which shows the high potential of β-TCP and HAp particle reinforcement combined with CA as a cross-linking agent. Furthermore, the reduced modulus of elasticity was increased by up to 288%. Results of the MTT assay on L929 cells have revealed that the hybrid composite GB-TCP-HA-CA was not cytotoxic. These results showed that GB cross-linked with CA and reinforced with different calcium phosphates presents a valuable novel material with potential applications in dentistry.",
publisher = "MDPI",
journal = "Polymers",
title = "Citric Acid Cross-Linked Gelatin-Based Composites with Improved Microhardness",
number = "8",
pages = "1077",
volume = "16",
doi = "10.3390/polym16081077"
}

Taboun, A., Jovanović, M., Petrović, M., Stajčić, I., Pešić, I., Stojanović, D. B.,& Radojević, V.. (2024). Citric Acid Cross-Linked Gelatin-Based Composites with Improved Microhardness. in Polymers
MDPI., 16(8), 1077.
https://doi.org/10.3390/polym16081077

Taboun A, Jovanović M, Petrović M, Stajčić I, Pešić I, Stojanović DB, Radojević V. Citric Acid Cross-Linked Gelatin-Based Composites with Improved Microhardness. in Polymers. 2024;16(8):1077.
doi:10.3390/polym16081077 .

Taboun, Abdulrraouf, Jovanović, Marija, Petrović, Miloš, Stajčić, Ivana, Pešić, Ivan, Stojanović, Dušica B., Radojević, Vesna, "Citric Acid Cross-Linked Gelatin-Based Composites with Improved Microhardness" in Polymers, 16, no. 8 (2024):1077,
https://doi.org/10.3390/polym16081077 . .

TY  - CONF
AU  - Jovanović, Marija
AU  - Petrović, Miloš
AU  - Stojanović, Dušica
AU  - Radulović, Nataša
AU  - Pantelić, Danijel
AU  - Radojević, Vesna
AU  - Uskoković, Petar
PY  - 2024
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7441
AB  - The objective of this study was to processand evaluatea suitablescaffold matrix system for drug delivery and tissue regeneration. Abioinspired approachwas applied.Thescaffold based onnatural polymer gelatin,blended  with polyvinylpyrrolidone,and crosslinked  by  genipin,was  3D  printed  by semi-solid  extrusion(SSE).This  3D printing techniquedoes not require high temperature or UV curing, so it allows the use  ofthermo-and UV-sensitive drugs, cells, or other biological components.The influence of genipin, a natural crosslinking agent, and itscontent on the mechanical properties and the cytotoxicity of obtained scaffolds were investigated.
PB  - Savez hemijskih inženjera Srbije
C3  - Hemijska industrija - Supplementary Issue - ExcellMater Conference 2024 Abstracts
T1  - Evaluation of crosslinked gelatin-polyvinylpyrrolidone scaffold for application in drug delivery and tissue engineering
IS  - 1S
SP  - 25
VL  - 78
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7441
ER  - 

@conference{
author = "Jovanović, Marija and Petrović, Miloš and Stojanović, Dušica and Radulović, Nataša and Pantelić, Danijel and Radojević, Vesna and Uskoković, Petar",
year = "2024",
abstract = "The objective of this study was to processand evaluatea suitablescaffold matrix system for drug delivery and tissue regeneration. Abioinspired approachwas applied.Thescaffold based onnatural polymer gelatin,blended  with polyvinylpyrrolidone,and crosslinked  by  genipin,was  3D  printed  by semi-solid  extrusion(SSE).This  3D printing techniquedoes not require high temperature or UV curing, so it allows the use  ofthermo-and UV-sensitive drugs, cells, or other biological components.The influence of genipin, a natural crosslinking agent, and itscontent on the mechanical properties and the cytotoxicity of obtained scaffolds were investigated.",
publisher = "Savez hemijskih inženjera Srbije",
journal = "Hemijska industrija - Supplementary Issue - ExcellMater Conference 2024 Abstracts",
title = "Evaluation of crosslinked gelatin-polyvinylpyrrolidone scaffold for application in drug delivery and tissue engineering",
number = "1S",
pages = "25",
volume = "78",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7441"
}

Jovanović, M., Petrović, M., Stojanović, D., Radulović, N., Pantelić, D., Radojević, V.,& Uskoković, P.. (2024). Evaluation of crosslinked gelatin-polyvinylpyrrolidone scaffold for application in drug delivery and tissue engineering. in Hemijska industrija - Supplementary Issue - ExcellMater Conference 2024 Abstracts
Savez hemijskih inženjera Srbije., 78(1S), 25.
https://hdl.handle.net/21.15107/rcub_technorep_7441

Jovanović M, Petrović M, Stojanović D, Radulović N, Pantelić D, Radojević V, Uskoković P. Evaluation of crosslinked gelatin-polyvinylpyrrolidone scaffold for application in drug delivery and tissue engineering. in Hemijska industrija - Supplementary Issue - ExcellMater Conference 2024 Abstracts. 2024;78(1S):25.
https://hdl.handle.net/21.15107/rcub_technorep_7441 .

Jovanović, Marija, Petrović, Miloš, Stojanović, Dušica, Radulović, Nataša, Pantelić, Danijel, Radojević, Vesna, Uskoković, Petar, "Evaluation of crosslinked gelatin-polyvinylpyrrolidone scaffold for application in drug delivery and tissue engineering" in Hemijska industrija - Supplementary Issue - ExcellMater Conference 2024 Abstracts, 78, no. 1S (2024):25,
https://hdl.handle.net/21.15107/rcub_technorep_7441 .

TY  - JOUR
AU  - Stojanović, Dušica
AU  - Ivanovska, Aleksandra
AU  - Barać, Nemanja
AU  - Dimić-Mišić, Katarina
AU  - Kostić, Mirjana
AU  - Radojević, Vesna
AU  - Janaćković, Đorđe
AU  - Uskoković, Petar
AU  - Barceló, Ernest
AU  - Gane, Patrick
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6571
AB  - Ionic liquid 1-butyl-3-methylimidazolium chloride [BMIM][Cl] was used to prepare cellulose (CELL), cellulose/polycaprolactone (CELL/PCL), cellulose/polycaprolactone/keratin (CELL/PCL/KER), and cellulose/polycaprolactone/keratin/ground calcium carbonate (CELL/PCL/KER/GCC) biodegradable mulch films. Attenuated Total Reflectance Fourier-Transform Infrared (ATR-FTIR) spectroscopy, optical microscopy, and Field-Emission Scanning Electron Microscopy (FE-SEM) were used to verify the films’ surface chemistry and morphology. Mulch film made of only cellulose regenerated from ionic liquid solution exhibited the highest tensile strength (75.3 ± 2.1 MPa) and modulus of elasticity of 944.4 ± 2.0 MPa. Among samples containing PCL, CELL/PCL/KER/GCC is characterized by the highest tensile strength (15.8 ± 0.4 MPa) and modulus of elasticity (687.5 ± 16.6 MPa). The film’s breaking strain decreased for all samples containing PCL upon the addition of KER and KER/GCC. The melting temperature of pure PCL is 62.3 °C, whereas that of CELL/PCL film has a slight tendency for melting point depression (61.0 °C), which is a characteristic of partially miscible polymer blends. Furthermore, Differential Scanning Calorimetry (DSC) analysis revealed that the addition of KER or KER/GCC to CELL/PCL films resulted in an increment in melting temperature from 61.0 to 62.6 and 68.9 °C and an improvement in sample crystallinity by 2.2 and 3.0 times, respectively. The light transmittance of all studied samples was greater than 60%. The reported method for mulch film preparation is green and recyclable ([BMIM][Cl] can be recovered), and the inclusion of KER derived by extraction from waste chicken feathers enables conversion to organic biofertilizer. The findings of this study contribute to sustainable agriculture by providing nutrients that enhance the growth rate of plants, and hence food production, while reducing environmental pressure. The addition of GCC furthermore provides a source of Ca2+ for plant micronutrition and a supplementary control of soil pH.
PB  - MDPI
T2  - Polymers
T1  - Biodegradable Cellulose/Polycaprolactone/Keratin/Calcium Carbonate Mulch Films Prepared in Imidazolium-Based Ionic Liquid
IS  - 12
SP  - 2729
VL  - 15
DO  - 10.3390/polym15122729
ER  - 

@article{
author = "Stojanović, Dušica and Ivanovska, Aleksandra and Barać, Nemanja and Dimić-Mišić, Katarina and Kostić, Mirjana and Radojević, Vesna and Janaćković, Đorđe and Uskoković, Petar and Barceló, Ernest and Gane, Patrick",
year = "2023",
abstract = "Ionic liquid 1-butyl-3-methylimidazolium chloride [BMIM][Cl] was used to prepare cellulose (CELL), cellulose/polycaprolactone (CELL/PCL), cellulose/polycaprolactone/keratin (CELL/PCL/KER), and cellulose/polycaprolactone/keratin/ground calcium carbonate (CELL/PCL/KER/GCC) biodegradable mulch films. Attenuated Total Reflectance Fourier-Transform Infrared (ATR-FTIR) spectroscopy, optical microscopy, and Field-Emission Scanning Electron Microscopy (FE-SEM) were used to verify the films’ surface chemistry and morphology. Mulch film made of only cellulose regenerated from ionic liquid solution exhibited the highest tensile strength (75.3 ± 2.1 MPa) and modulus of elasticity of 944.4 ± 2.0 MPa. Among samples containing PCL, CELL/PCL/KER/GCC is characterized by the highest tensile strength (15.8 ± 0.4 MPa) and modulus of elasticity (687.5 ± 16.6 MPa). The film’s breaking strain decreased for all samples containing PCL upon the addition of KER and KER/GCC. The melting temperature of pure PCL is 62.3 °C, whereas that of CELL/PCL film has a slight tendency for melting point depression (61.0 °C), which is a characteristic of partially miscible polymer blends. Furthermore, Differential Scanning Calorimetry (DSC) analysis revealed that the addition of KER or KER/GCC to CELL/PCL films resulted in an increment in melting temperature from 61.0 to 62.6 and 68.9 °C and an improvement in sample crystallinity by 2.2 and 3.0 times, respectively. The light transmittance of all studied samples was greater than 60%. The reported method for mulch film preparation is green and recyclable ([BMIM][Cl] can be recovered), and the inclusion of KER derived by extraction from waste chicken feathers enables conversion to organic biofertilizer. The findings of this study contribute to sustainable agriculture by providing nutrients that enhance the growth rate of plants, and hence food production, while reducing environmental pressure. The addition of GCC furthermore provides a source of Ca2+ for plant micronutrition and a supplementary control of soil pH.",
publisher = "MDPI",
journal = "Polymers",
title = "Biodegradable Cellulose/Polycaprolactone/Keratin/Calcium Carbonate Mulch Films Prepared in Imidazolium-Based Ionic Liquid",
number = "12",
pages = "2729",
volume = "15",
doi = "10.3390/polym15122729"
}

Stojanović, D., Ivanovska, A., Barać, N., Dimić-Mišić, K., Kostić, M., Radojević, V., Janaćković, Đ., Uskoković, P., Barceló, E.,& Gane, P.. (2023). Biodegradable Cellulose/Polycaprolactone/Keratin/Calcium Carbonate Mulch Films Prepared in Imidazolium-Based Ionic Liquid. in Polymers
MDPI., 15(12), 2729.
https://doi.org/10.3390/polym15122729

Stojanović D, Ivanovska A, Barać N, Dimić-Mišić K, Kostić M, Radojević V, Janaćković Đ, Uskoković P, Barceló E, Gane P. Biodegradable Cellulose/Polycaprolactone/Keratin/Calcium Carbonate Mulch Films Prepared in Imidazolium-Based Ionic Liquid. in Polymers. 2023;15(12):2729.
doi:10.3390/polym15122729 .

Stojanović, Dušica, Ivanovska, Aleksandra, Barać, Nemanja, Dimić-Mišić, Katarina, Kostić, Mirjana, Radojević, Vesna, Janaćković, Đorđe, Uskoković, Petar, Barceló, Ernest, Gane, Patrick, "Biodegradable Cellulose/Polycaprolactone/Keratin/Calcium Carbonate Mulch Films Prepared in Imidazolium-Based Ionic Liquid" in Polymers, 15, no. 12 (2023):2729,
https://doi.org/10.3390/polym15122729 . .

TY  - CONF
AU  - Ivanovska, Aleksandra
AU  - Stojanović, Dušica
AU  - Barać, Nemanja
AU  - Dimić-Mišić, Katarina
AU  - Kostić, Mirjana
AU  - Radojević, Vesna
AU  - Uskoković, Petar
AU  - Janaćković, Đorđe
AU  - Barcelo, Ernesto
AU  - Gane, Patrick
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6820
AB  - Biodegradable mulch films from cellulose (CELL), cellulose/polycaprolactone (CELL/PCL),
cellulose/polycaprolactone/keratin (CELL/PCL/KER) and cellulose/polycaprolactone/keratin/ground calcium carbonate (CELL/PCL/KER/GCC) were prepared using Ionic liquid as a green
solvent. Pure cellulose biopolymer is characterised by better mechanical properties (tensile
strength - force per unit cross-sectional area at breakage - of 75.3 MPa and modulus of elasticity
of 944.4 MPa) than the other studied samples which is attributed to the formation of partially
miscible polymer blends. Among samples containing PCL, CELL/PCL/KER/GCC has the highest
tensile strength and modulus of elasticity. The addition of KER or KER/GCC to CELL/PCL films
resulted in an increment in melting temperature and an improvement of sample crystallinity. The
light transmittance of all films was >60 %. The incorporation of KER enhanced the
biodegradability of the biocomposites, while KER/GCC addition slightly inhibited degradation
due to an increased hydrophobicity and crystallisation growth of semi-crystalline biopolymers.
The reported method for mulch film preparation is green and recyclable, and, when including a
readily available source of KER, such as by extraction from waste chicken feathers, enables
conversion to organic biofertiliser. The findings of this study contributed to sustainable agriculture
by providing nutrients that enhance the growth speed of the plant, and hence food production, and
reduce environmental pressure. Inclusion of GCC additionally provides not only Ca2+ for plant
consumption but also soil pH control.
PB  - Belgrade : Materials Research Society of Serbia
C3  - Programme and The Book of Abstracts / Twenty-fourth Annual Conference YUCOMAT 2023, Herceg Novi, Montenegro, September 4 - 8, 2023
T1  - Biodegradable mulch films obtained from unique combinations of cellulose, polycaprolactone, keratin and calcium carbonate
SP  - 135
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6820
ER  - 

@conference{
author = "Ivanovska, Aleksandra and Stojanović, Dušica and Barać, Nemanja and Dimić-Mišić, Katarina and Kostić, Mirjana and Radojević, Vesna and Uskoković, Petar and Janaćković, Đorđe and Barcelo, Ernesto and Gane, Patrick",
year = "2023",
abstract = "Biodegradable mulch films from cellulose (CELL), cellulose/polycaprolactone (CELL/PCL),
cellulose/polycaprolactone/keratin (CELL/PCL/KER) and cellulose/polycaprolactone/keratin/ground calcium carbonate (CELL/PCL/KER/GCC) were prepared using Ionic liquid as a green
solvent. Pure cellulose biopolymer is characterised by better mechanical properties (tensile
strength - force per unit cross-sectional area at breakage - of 75.3 MPa and modulus of elasticity
of 944.4 MPa) than the other studied samples which is attributed to the formation of partially
miscible polymer blends. Among samples containing PCL, CELL/PCL/KER/GCC has the highest
tensile strength and modulus of elasticity. The addition of KER or KER/GCC to CELL/PCL films
resulted in an increment in melting temperature and an improvement of sample crystallinity. The
light transmittance of all films was >60 %. The incorporation of KER enhanced the
biodegradability of the biocomposites, while KER/GCC addition slightly inhibited degradation
due to an increased hydrophobicity and crystallisation growth of semi-crystalline biopolymers.
The reported method for mulch film preparation is green and recyclable, and, when including a
readily available source of KER, such as by extraction from waste chicken feathers, enables
conversion to organic biofertiliser. The findings of this study contributed to sustainable agriculture
by providing nutrients that enhance the growth speed of the plant, and hence food production, and
reduce environmental pressure. Inclusion of GCC additionally provides not only Ca2+ for plant
consumption but also soil pH control.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "Programme and The Book of Abstracts / Twenty-fourth Annual Conference YUCOMAT 2023, Herceg Novi, Montenegro, September 4 - 8, 2023",
title = "Biodegradable mulch films obtained from unique combinations of cellulose, polycaprolactone, keratin and calcium carbonate",
pages = "135",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6820"
}

Ivanovska, A., Stojanović, D., Barać, N., Dimić-Mišić, K., Kostić, M., Radojević, V., Uskoković, P., Janaćković, Đ., Barcelo, E.,& Gane, P.. (2023). Biodegradable mulch films obtained from unique combinations of cellulose, polycaprolactone, keratin and calcium carbonate. in Programme and The Book of Abstracts / Twenty-fourth Annual Conference YUCOMAT 2023, Herceg Novi, Montenegro, September 4 - 8, 2023
Belgrade : Materials Research Society of Serbia., 135.
https://hdl.handle.net/21.15107/rcub_technorep_6820

Ivanovska A, Stojanović D, Barać N, Dimić-Mišić K, Kostić M, Radojević V, Uskoković P, Janaćković Đ, Barcelo E, Gane P. Biodegradable mulch films obtained from unique combinations of cellulose, polycaprolactone, keratin and calcium carbonate. in Programme and The Book of Abstracts / Twenty-fourth Annual Conference YUCOMAT 2023, Herceg Novi, Montenegro, September 4 - 8, 2023. 2023;:135.
https://hdl.handle.net/21.15107/rcub_technorep_6820 .

Ivanovska, Aleksandra, Stojanović, Dušica, Barać, Nemanja, Dimić-Mišić, Katarina, Kostić, Mirjana, Radojević, Vesna, Uskoković, Petar, Janaćković, Đorđe, Barcelo, Ernesto, Gane, Patrick, "Biodegradable mulch films obtained from unique combinations of cellulose, polycaprolactone, keratin and calcium carbonate" in Programme and The Book of Abstracts / Twenty-fourth Annual Conference YUCOMAT 2023, Herceg Novi, Montenegro, September 4 - 8, 2023 (2023):135,
https://hdl.handle.net/21.15107/rcub_technorep_6820 .

TY  - JOUR
AU  - Radisavljević, Anđela
AU  - Stojanović, Dušica B.
AU  - Petrović, Miloš
AU  - Radojević, Vesna
AU  - Uskoković, Petar
AU  - Rajilić-Stojanović, Mirjana
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5295
AB  - In this study, polycaprolactone (PCL), as a biocompatible polymer was functionalized by addition of medicinal plant extract- Achillea millefolium L. (yarrow). Nanofiber mats were fabricated from PCL solutions containing dry yarrow extract in four concentrations (5%, 10%, 15%, and 20% relative to the weight of the polymer) by using blend electrospinning method. The nanofibers were characterized for their biological, mechanical and drug release behavior. In vitro release of yarrow polyphenols from the electrospun PCL nanofibers over a period of 5 days showed the release of up to 98% of the total loaded polyphenols. The released polyphenols retained its antioxidant activity, which was determined by DPPH assay. Electrospun PCL/yarrow nanofiber mats exhibited the antibacterial effect against Staphylococcus aureus, but had no effect on the growth of Pseudomonas aeruginosa. All PCL/yarrow nanofiber mats had improved mechanical properties compared to the neat PCL nanofibers, as evident by an increase in Young's modulus of elasticity (up to 5.7 times), the tensile strength (up to 5.5 times), and the strain at break (up to 1.45 times). Based on our results, yarrow-loaded PCL nanofiber mats appeared to be multi-functional biomaterials suitable for the production of catheter-coating materials, patches, or gauzes with antibacterial and antioxidant properties.
PB  - John Wiley and Sons Inc.
T2  - Journal of Biomedical Materials Research - Part A
T1  - Electrospun polycaprolactone nanofibers functionalized with Achillea millefolium extract yield biomaterial with antibacterial, antioxidant and improved mechanical properties
EP  - 974
IS  - 7
SP  - 962
VL  - 111
DO  - 10.1002/jbm.a.37481
ER  - 

@article{
author = "Radisavljević, Anđela and Stojanović, Dušica B. and Petrović, Miloš and Radojević, Vesna and Uskoković, Petar and Rajilić-Stojanović, Mirjana",
year = "2023",
abstract = "In this study, polycaprolactone (PCL), as a biocompatible polymer was functionalized by addition of medicinal plant extract- Achillea millefolium L. (yarrow). Nanofiber mats were fabricated from PCL solutions containing dry yarrow extract in four concentrations (5%, 10%, 15%, and 20% relative to the weight of the polymer) by using blend electrospinning method. The nanofibers were characterized for their biological, mechanical and drug release behavior. In vitro release of yarrow polyphenols from the electrospun PCL nanofibers over a period of 5 days showed the release of up to 98% of the total loaded polyphenols. The released polyphenols retained its antioxidant activity, which was determined by DPPH assay. Electrospun PCL/yarrow nanofiber mats exhibited the antibacterial effect against Staphylococcus aureus, but had no effect on the growth of Pseudomonas aeruginosa. All PCL/yarrow nanofiber mats had improved mechanical properties compared to the neat PCL nanofibers, as evident by an increase in Young's modulus of elasticity (up to 5.7 times), the tensile strength (up to 5.5 times), and the strain at break (up to 1.45 times). Based on our results, yarrow-loaded PCL nanofiber mats appeared to be multi-functional biomaterials suitable for the production of catheter-coating materials, patches, or gauzes with antibacterial and antioxidant properties.",
publisher = "John Wiley and Sons Inc.",
journal = "Journal of Biomedical Materials Research - Part A",
title = "Electrospun polycaprolactone nanofibers functionalized with Achillea millefolium extract yield biomaterial with antibacterial, antioxidant and improved mechanical properties",
pages = "974-962",
number = "7",
volume = "111",
doi = "10.1002/jbm.a.37481"
}

Radisavljević, A., Stojanović, D. B., Petrović, M., Radojević, V., Uskoković, P.,& Rajilić-Stojanović, M.. (2023). Electrospun polycaprolactone nanofibers functionalized with Achillea millefolium extract yield biomaterial with antibacterial, antioxidant and improved mechanical properties. in Journal of Biomedical Materials Research - Part A
John Wiley and Sons Inc.., 111(7), 962-974.
https://doi.org/10.1002/jbm.a.37481

Radisavljević A, Stojanović DB, Petrović M, Radojević V, Uskoković P, Rajilić-Stojanović M. Electrospun polycaprolactone nanofibers functionalized with Achillea millefolium extract yield biomaterial with antibacterial, antioxidant and improved mechanical properties. in Journal of Biomedical Materials Research - Part A. 2023;111(7):962-974.
doi:10.1002/jbm.a.37481 .

Radisavljević, Anđela, Stojanović, Dušica B., Petrović, Miloš, Radojević, Vesna, Uskoković, Petar, Rajilić-Stojanović, Mirjana, "Electrospun polycaprolactone nanofibers functionalized with Achillea millefolium extract yield biomaterial with antibacterial, antioxidant and improved mechanical properties" in Journal of Biomedical Materials Research - Part A, 111, no. 7 (2023):962-974,
https://doi.org/10.1002/jbm.a.37481 . .

TY  - JOUR
AU  - Peleš Tadić, Adriana
AU  - Blagojević, Vladimir A.
AU  - Stojanović, Dušica
AU  - Ostojić, Sanja B.
AU  - Tasić, Nikola
AU  - Kosanović, Darko
AU  - Uskoković, Petar
AU  - Pavlović, Vladimir B.
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5264
AB  - Poly(vinylidenefluoride)–ZnO (PVDF–ZnO) nanocomposites with mechanically activated ZnO nanoparticle fillers were investigated using thermal and mechanical analysis and AFM and PFM. Differential scanning calorimetry (DSC) investigated the effect of ZnO nanoparticles on the crystallinity of the polymer, under controlled heating and cooling. Atomic force (AFM) microscopy was used to record the surfaces of the samples. Nanocomposite surface roughness shows the presence of the different phases inside of the matrix, where rough samples contain a higher proportion of the β phase. PFM was performed to investigate the piezoresponse of the composites. Nanoidentation showed that the mechanical activation of the filler (ZnO) increases the Young modulus with the activation time. Molecular simulations in periodic systems (PVDF–ZnO spherical nanocluster and nanocylinder composite) were used to investigate the influence of particle size and shape on the Young modulus of different phases of PVDF.
PB  - Elsevier Ltd
T2  - Materials Science and Engineering B: Solid-State Materials for Advanced Technology
T1  - Nanomechanical properties of PVDF–ZnO polymer nanocomposite
SP  - 116126
VL  - 287
DO  - 10.1016/j.mseb.2022.116126
ER  - 

@article{
author = "Peleš Tadić, Adriana and Blagojević, Vladimir A. and Stojanović, Dušica and Ostojić, Sanja B. and Tasić, Nikola and Kosanović, Darko and Uskoković, Petar and Pavlović, Vladimir B.",
year = "2023",
abstract = "Poly(vinylidenefluoride)–ZnO (PVDF–ZnO) nanocomposites with mechanically activated ZnO nanoparticle fillers were investigated using thermal and mechanical analysis and AFM and PFM. Differential scanning calorimetry (DSC) investigated the effect of ZnO nanoparticles on the crystallinity of the polymer, under controlled heating and cooling. Atomic force (AFM) microscopy was used to record the surfaces of the samples. Nanocomposite surface roughness shows the presence of the different phases inside of the matrix, where rough samples contain a higher proportion of the β phase. PFM was performed to investigate the piezoresponse of the composites. Nanoidentation showed that the mechanical activation of the filler (ZnO) increases the Young modulus with the activation time. Molecular simulations in periodic systems (PVDF–ZnO spherical nanocluster and nanocylinder composite) were used to investigate the influence of particle size and shape on the Young modulus of different phases of PVDF.",
publisher = "Elsevier Ltd",
journal = "Materials Science and Engineering B: Solid-State Materials for Advanced Technology",
title = "Nanomechanical properties of PVDF–ZnO polymer nanocomposite",
pages = "116126",
volume = "287",
doi = "10.1016/j.mseb.2022.116126"
}

Peleš Tadić, A., Blagojević, V. A., Stojanović, D., Ostojić, S. B., Tasić, N., Kosanović, D., Uskoković, P.,& Pavlović, V. B.. (2023). Nanomechanical properties of PVDF–ZnO polymer nanocomposite. in Materials Science and Engineering B: Solid-State Materials for Advanced Technology
Elsevier Ltd., 287, 116126.
https://doi.org/10.1016/j.mseb.2022.116126

Peleš Tadić A, Blagojević VA, Stojanović D, Ostojić SB, Tasić N, Kosanović D, Uskoković P, Pavlović VB. Nanomechanical properties of PVDF–ZnO polymer nanocomposite. in Materials Science and Engineering B: Solid-State Materials for Advanced Technology. 2023;287:116126.
doi:10.1016/j.mseb.2022.116126 .

Peleš Tadić, Adriana, Blagojević, Vladimir A., Stojanović, Dušica, Ostojić, Sanja B., Tasić, Nikola, Kosanović, Darko, Uskoković, Petar, Pavlović, Vladimir B., "Nanomechanical properties of PVDF–ZnO polymer nanocomposite" in Materials Science and Engineering B: Solid-State Materials for Advanced Technology, 287 (2023):116126,
https://doi.org/10.1016/j.mseb.2022.116126 . .

TY  - JOUR
AU  - Nowak, Mariusz
AU  - Semba, Damian
AU  - Mišić, Dušan
AU  - Półbrat, Tomasz
AU  - Stojanović, Dušica
AU  - Stanojević, Slavoljub
AU  - Trusek, Anna
AU  - Žižović, Irena
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6614
AB  - The study reports an effluent-free, green process for the production of materials with favorable antibiofilm properties by cellulose acetate grafting with quaternary ammonium compounds in supercritical carbon dioxide. Two quaternary ammonium compounds, N-(2-Hydroxyethyl)-N,N-dimethylundecan-1-aminium Bromide and N-(11-Hydroxyundecanyl-N,N-dimethyltetradecan- 1-aminium Bromide, were synthesized and chemically attached to cellulose acetate via hexamethylene diisocyanate as a linker under the conditions of 30 MPa and 70 °C. The polymer modification occurred in its whole volume. The chemical conversion led to a decrease in the degree of crystallinity and the appearance of a rugged polymer surface. However, the cross-section imaging of the newly obtained materials revealed a compact polymer structure. The functionalized materials acquired hydrophobic properties. Microbiological tests showed the impossibility of Staphylococcus aureus ATCC 29213, Methicillin-resistant Staphylococcus aureus ATCC 43300, Escherichia coli ATCC 10536, and Salmonella Enteritidis ATCC 13076 attachment to the material obtained by the cellulose acetate grafting procedure with N-(11-Hydroxyundecanyl-N,N-dimethyltetradecan- 1-aminium Bromide.
PB  - Elsevier B.V.
T2  - Journal of Supercritical Fluids
T1  - The transformation of cellulose acetate into a new biocidal polymer by effluent-free grafting in supercritical carbon dioxide
SP  - 106058
VL  - 202
DO  - 10.1016/j.supflu.2023.106058
ER  - 

@article{
author = "Nowak, Mariusz and Semba, Damian and Mišić, Dušan and Półbrat, Tomasz and Stojanović, Dušica and Stanojević, Slavoljub and Trusek, Anna and Žižović, Irena",
year = "2023",
abstract = "The study reports an effluent-free, green process for the production of materials with favorable antibiofilm properties by cellulose acetate grafting with quaternary ammonium compounds in supercritical carbon dioxide. Two quaternary ammonium compounds, N-(2-Hydroxyethyl)-N,N-dimethylundecan-1-aminium Bromide and N-(11-Hydroxyundecanyl-N,N-dimethyltetradecan- 1-aminium Bromide, were synthesized and chemically attached to cellulose acetate via hexamethylene diisocyanate as a linker under the conditions of 30 MPa and 70 °C. The polymer modification occurred in its whole volume. The chemical conversion led to a decrease in the degree of crystallinity and the appearance of a rugged polymer surface. However, the cross-section imaging of the newly obtained materials revealed a compact polymer structure. The functionalized materials acquired hydrophobic properties. Microbiological tests showed the impossibility of Staphylococcus aureus ATCC 29213, Methicillin-resistant Staphylococcus aureus ATCC 43300, Escherichia coli ATCC 10536, and Salmonella Enteritidis ATCC 13076 attachment to the material obtained by the cellulose acetate grafting procedure with N-(11-Hydroxyundecanyl-N,N-dimethyltetradecan- 1-aminium Bromide.",
publisher = "Elsevier B.V.",
journal = "Journal of Supercritical Fluids",
title = "The transformation of cellulose acetate into a new biocidal polymer by effluent-free grafting in supercritical carbon dioxide",
pages = "106058",
volume = "202",
doi = "10.1016/j.supflu.2023.106058"
}

Nowak, M., Semba, D., Mišić, D., Półbrat, T., Stojanović, D., Stanojević, S., Trusek, A.,& Žižović, I.. (2023). The transformation of cellulose acetate into a new biocidal polymer by effluent-free grafting in supercritical carbon dioxide. in Journal of Supercritical Fluids
Elsevier B.V.., 202, 106058.
https://doi.org/10.1016/j.supflu.2023.106058

Nowak M, Semba D, Mišić D, Półbrat T, Stojanović D, Stanojević S, Trusek A, Žižović I. The transformation of cellulose acetate into a new biocidal polymer by effluent-free grafting in supercritical carbon dioxide. in Journal of Supercritical Fluids. 2023;202:106058.
doi:10.1016/j.supflu.2023.106058 .

Nowak, Mariusz, Semba, Damian, Mišić, Dušan, Półbrat, Tomasz, Stojanović, Dušica, Stanojević, Slavoljub, Trusek, Anna, Žižović, Irena, "The transformation of cellulose acetate into a new biocidal polymer by effluent-free grafting in supercritical carbon dioxide" in Journal of Supercritical Fluids, 202 (2023):106058,
https://doi.org/10.1016/j.supflu.2023.106058 . .

TY  - JOUR
AU  - Salević-Jelić, Ana
AU  - Lević, Steva
AU  - Stojanović, Dušica
AU  - Jeremić, Sanja
AU  - Miletić, Dunja
AU  - Pantić, Milena
AU  - Pavlović, Vladimir
AU  - Sredović Ignjatović, Ivana
AU  - Uskoković, Petar
AU  - Nedović, Viktor
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5596
AB  - This study aimed to develop active, biodegradable materials for food packaging by incorporating sage extract (SE) within a zein-gelatin blend by electrospinning and solvent casting. The fabrication techniques, SE incorporation, and its content (5, 10% w/w) determined the materials’ properties. Electrospinning produced 0.36–0.53 mm thick, non-transparent fibrous mats (mean fiber diameter 1.12–1.36 µm). Solvent casting generated 0.34–0.41 mm thick, transparent continuous films. The analysis indicated the constituents’ compatibility, homogenous dispersion, and efficient SE incorporation without strong chemical interactions and phase separation. The solvent-cast films presented more ordered structures, higher mechanical resistance, elongation, and water vapor barrier performance than the electrospun mats. The SE-incorporating formulations showed phenolics’ delivery ability to food simulants influenced by structure, SE content, and media polarity. The electrospun mats expressed higher DPPH• radicals’ inhibition, while the solvent-cast films showed stronger Staphylococcus aureus and Escherichia coli growth inhibition, increased by SE incorporation. All formulations showed rapid complete bio-disintegration in compost (18–25 days).
PB  - Elsevier Ltd.
T2  - Food Packaging and Shelf Life
T1  - Biodegradable and active zein-gelatin-based electrospun mats and solvent-cast films incorporating sage extract: Formulation and comparative characterization
SP  - 101027
VL  - 35
DO  - 10.1016/j.fpsl.2023.101027
ER  - 

@article{
author = "Salević-Jelić, Ana and Lević, Steva and Stojanović, Dušica and Jeremić, Sanja and Miletić, Dunja and Pantić, Milena and Pavlović, Vladimir and Sredović Ignjatović, Ivana and Uskoković, Petar and Nedović, Viktor",
year = "2023",
abstract = "This study aimed to develop active, biodegradable materials for food packaging by incorporating sage extract (SE) within a zein-gelatin blend by electrospinning and solvent casting. The fabrication techniques, SE incorporation, and its content (5, 10% w/w) determined the materials’ properties. Electrospinning produced 0.36–0.53 mm thick, non-transparent fibrous mats (mean fiber diameter 1.12–1.36 µm). Solvent casting generated 0.34–0.41 mm thick, transparent continuous films. The analysis indicated the constituents’ compatibility, homogenous dispersion, and efficient SE incorporation without strong chemical interactions and phase separation. The solvent-cast films presented more ordered structures, higher mechanical resistance, elongation, and water vapor barrier performance than the electrospun mats. The SE-incorporating formulations showed phenolics’ delivery ability to food simulants influenced by structure, SE content, and media polarity. The electrospun mats expressed higher DPPH• radicals’ inhibition, while the solvent-cast films showed stronger Staphylococcus aureus and Escherichia coli growth inhibition, increased by SE incorporation. All formulations showed rapid complete bio-disintegration in compost (18–25 days).",
publisher = "Elsevier Ltd.",
journal = "Food Packaging and Shelf Life",
title = "Biodegradable and active zein-gelatin-based electrospun mats and solvent-cast films incorporating sage extract: Formulation and comparative characterization",
pages = "101027",
volume = "35",
doi = "10.1016/j.fpsl.2023.101027"
}

Salević-Jelić, A., Lević, S., Stojanović, D., Jeremić, S., Miletić, D., Pantić, M., Pavlović, V., Sredović Ignjatović, I., Uskoković, P.,& Nedović, V.. (2023). Biodegradable and active zein-gelatin-based electrospun mats and solvent-cast films incorporating sage extract: Formulation and comparative characterization. in Food Packaging and Shelf Life
Elsevier Ltd.., 35, 101027.
https://doi.org/10.1016/j.fpsl.2023.101027

Salević-Jelić A, Lević S, Stojanović D, Jeremić S, Miletić D, Pantić M, Pavlović V, Sredović Ignjatović I, Uskoković P, Nedović V. Biodegradable and active zein-gelatin-based electrospun mats and solvent-cast films incorporating sage extract: Formulation and comparative characterization. in Food Packaging and Shelf Life. 2023;35:101027.
doi:10.1016/j.fpsl.2023.101027 .

Salević-Jelić, Ana, Lević, Steva, Stojanović, Dušica, Jeremić, Sanja, Miletić, Dunja, Pantić, Milena, Pavlović, Vladimir, Sredović Ignjatović, Ivana, Uskoković, Petar, Nedović, Viktor, "Biodegradable and active zein-gelatin-based electrospun mats and solvent-cast films incorporating sage extract: Formulation and comparative characterization" in Food Packaging and Shelf Life, 35 (2023):101027,
https://doi.org/10.1016/j.fpsl.2023.101027 . .

TY  - JOUR
AU  - Salević, Ana
AU  - Stojanović, Dušica
AU  - Lević, Steva
AU  - Pantić, Milena
AU  - Đorđević, Verica
AU  - Pešić, Radojica
AU  - Bugarski, Branko
AU  - Pavlović, Vladimir
AU  - Uskoković, Petar
AU  - Nedović, Viktor
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5008
AB  - In this study, in order to develop zein-based, edible, functional food-contact materials in different forms incorporating sage extract (10, 20, and 30%), solvent casting and electrospinning were employed. The study aimed to assess the effects of the applied techniques and the extract's incorporation on the materials' properties. The solvent casting generated continuous and compact films, where the extract's incorporation provided more homogenous surfaces. The electrospinning resulted in non-woven mats composed of ribbon-like fibers in the range of 1.275-1.829 mu m, while the extract's incorporation provided thinner and branched fibers. The results indicated the compatibility between the materials' constituents, and efficient and homogenous extract incorporation within the zein matrices, with more probable interactions occurring during the solvent casting. All of the formulations had a high dry matter content, whereas the mats and the formulations incorporating the extract had higher solubility and swelling in water. The films and mats presented similar DPPH center dot and ABTS(center dot+) radical scavenging abilities, while the influence on Staphylococcus aureus and Salmonella enterica subsp. enterica serovar Typhimurium bacteria, and the growth inhibition, were complex. The antioxidant and antibacterial activity of the materials were more potent after the extract's incorporation. Overall, the results highlight the potential of the developed edible materials for use as food-contact materials with active/bioactive functionality.
PB  - MDPI
T2  - Foods
T1  - The Structuring of Sage (Salvia officinalis L.) Extract-Incorporating Edible Zein-Based Materials with Antioxidant and Antibacterial Functionality by Solvent Casting versus Electrospinning
IS  - 3
SP  - 390
VL  - 11
DO  - 10.3390/foods11030390
ER  - 

@article{
author = "Salević, Ana and Stojanović, Dušica and Lević, Steva and Pantić, Milena and Đorđević, Verica and Pešić, Radojica and Bugarski, Branko and Pavlović, Vladimir and Uskoković, Petar and Nedović, Viktor",
year = "2022",
abstract = "In this study, in order to develop zein-based, edible, functional food-contact materials in different forms incorporating sage extract (10, 20, and 30%), solvent casting and electrospinning were employed. The study aimed to assess the effects of the applied techniques and the extract's incorporation on the materials' properties. The solvent casting generated continuous and compact films, where the extract's incorporation provided more homogenous surfaces. The electrospinning resulted in non-woven mats composed of ribbon-like fibers in the range of 1.275-1.829 mu m, while the extract's incorporation provided thinner and branched fibers. The results indicated the compatibility between the materials' constituents, and efficient and homogenous extract incorporation within the zein matrices, with more probable interactions occurring during the solvent casting. All of the formulations had a high dry matter content, whereas the mats and the formulations incorporating the extract had higher solubility and swelling in water. The films and mats presented similar DPPH center dot and ABTS(center dot+) radical scavenging abilities, while the influence on Staphylococcus aureus and Salmonella enterica subsp. enterica serovar Typhimurium bacteria, and the growth inhibition, were complex. The antioxidant and antibacterial activity of the materials were more potent after the extract's incorporation. Overall, the results highlight the potential of the developed edible materials for use as food-contact materials with active/bioactive functionality.",
publisher = "MDPI",
journal = "Foods",
title = "The Structuring of Sage (Salvia officinalis L.) Extract-Incorporating Edible Zein-Based Materials with Antioxidant and Antibacterial Functionality by Solvent Casting versus Electrospinning",
number = "3",
pages = "390",
volume = "11",
doi = "10.3390/foods11030390"
}

Salević, A., Stojanović, D., Lević, S., Pantić, M., Đorđević, V., Pešić, R., Bugarski, B., Pavlović, V., Uskoković, P.,& Nedović, V.. (2022). The Structuring of Sage (Salvia officinalis L.) Extract-Incorporating Edible Zein-Based Materials with Antioxidant and Antibacterial Functionality by Solvent Casting versus Electrospinning. in Foods
MDPI., 11(3), 390.
https://doi.org/10.3390/foods11030390

Salević A, Stojanović D, Lević S, Pantić M, Đorđević V, Pešić R, Bugarski B, Pavlović V, Uskoković P, Nedović V. The Structuring of Sage (Salvia officinalis L.) Extract-Incorporating Edible Zein-Based Materials with Antioxidant and Antibacterial Functionality by Solvent Casting versus Electrospinning. in Foods. 2022;11(3):390.
doi:10.3390/foods11030390 .

Salević, Ana, Stojanović, Dušica, Lević, Steva, Pantić, Milena, Đorđević, Verica, Pešić, Radojica, Bugarski, Branko, Pavlović, Vladimir, Uskoković, Petar, Nedović, Viktor, "The Structuring of Sage (Salvia officinalis L.) Extract-Incorporating Edible Zein-Based Materials with Antioxidant and Antibacterial Functionality by Solvent Casting versus Electrospinning" in Foods, 11, no. 3 (2022):390,
https://doi.org/10.3390/foods11030390 . .

TY  - JOUR
AU  - Pajnik, Jelena
AU  - Milovanović, Stoja
AU  - Stojanović, Dušica
AU  - Dimitrijević-Branković, Suzana
AU  - Janković-Častvan, Ivona
AU  - Uskoković, Petar
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4979
AB  - Outbreak of surgical infections and bacterial resistance against synthetic antibiotic has prompted research towards development of antibacterial medical devices. For that purpose, absorbable surgical sutures were impregnated with natural compound thymol using an environmentally friendly medium. The supercritical solvent impregnation process was performed at 35 degrees C and 10 MPa during 1, 2, 3 and 6 h, resulting in thymol loadings of 3.9-5.6%. All tested samples expressed antibacterial activity against E. coli and S. aureus. Release tests in PBS at 37 degrees C showed that impregnated material released loaded thymol in a gradual manner. While sutures impregnated during 6 h released complete amount of loaded thymol during 6 days, shorter impregnation process resulted in sutures that retained significant thymol amounts (similar to 20-40%) after 10 days of release test. The effect of proposed process on final material properties and its application were explained in detail using characterization techniques SEM, FTIR, DSC and DMA.
PB  - Elsevier B.V.
T2  - Journal of Supercritical Fluids
T1  - Utilization of supercritical carbon dioxide for development of antibacterial surgical sutures
SP  - 105490
VL  - 181
DO  - 10.1016/j.supflu.2021.105490
ER  - 

@article{
author = "Pajnik, Jelena and Milovanović, Stoja and Stojanović, Dušica and Dimitrijević-Branković, Suzana and Janković-Častvan, Ivona and Uskoković, Petar",
year = "2022",
abstract = "Outbreak of surgical infections and bacterial resistance against synthetic antibiotic has prompted research towards development of antibacterial medical devices. For that purpose, absorbable surgical sutures were impregnated with natural compound thymol using an environmentally friendly medium. The supercritical solvent impregnation process was performed at 35 degrees C and 10 MPa during 1, 2, 3 and 6 h, resulting in thymol loadings of 3.9-5.6%. All tested samples expressed antibacterial activity against E. coli and S. aureus. Release tests in PBS at 37 degrees C showed that impregnated material released loaded thymol in a gradual manner. While sutures impregnated during 6 h released complete amount of loaded thymol during 6 days, shorter impregnation process resulted in sutures that retained significant thymol amounts (similar to 20-40%) after 10 days of release test. The effect of proposed process on final material properties and its application were explained in detail using characterization techniques SEM, FTIR, DSC and DMA.",
publisher = "Elsevier B.V.",
journal = "Journal of Supercritical Fluids",
title = "Utilization of supercritical carbon dioxide for development of antibacterial surgical sutures",
pages = "105490",
volume = "181",
doi = "10.1016/j.supflu.2021.105490"
}

Pajnik, J., Milovanović, S., Stojanović, D., Dimitrijević-Branković, S., Janković-Častvan, I.,& Uskoković, P.. (2022). Utilization of supercritical carbon dioxide for development of antibacterial surgical sutures. in Journal of Supercritical Fluids
Elsevier B.V.., 181, 105490.
https://doi.org/10.1016/j.supflu.2021.105490

Pajnik J, Milovanović S, Stojanović D, Dimitrijević-Branković S, Janković-Častvan I, Uskoković P. Utilization of supercritical carbon dioxide for development of antibacterial surgical sutures. in Journal of Supercritical Fluids. 2022;181:105490.
doi:10.1016/j.supflu.2021.105490 .

Pajnik, Jelena, Milovanović, Stoja, Stojanović, Dušica, Dimitrijević-Branković, Suzana, Janković-Častvan, Ivona, Uskoković, Petar, "Utilization of supercritical carbon dioxide for development of antibacterial surgical sutures" in Journal of Supercritical Fluids, 181 (2022):105490,
https://doi.org/10.1016/j.supflu.2021.105490 . .

TY  - JOUR
AU  - Kostić, Mirjana
AU  - Imani, Monireh
AU  - Ivanovska, Aleksandra
AU  - Radojević, Vesna
AU  - Dimić-Mišić, Katarina
AU  - Barać, Nemanja
AU  - Stojanović, Dušica
AU  - Janaćković, Đorđe
AU  - Uskoković, Petar
AU  - Barcelo, Ernest
AU  - Gane, Patrick
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5138
AB  - Cellulose-fibre lifecycle is severely limited within today’s recycling methodology. Feedstock cellulose and filler abound in products considered uneconomic, unsuitable for standard deinking or too weak for original product re-use. Regeneration of cellulose from ionic liquid (IL) solution offers a novel valorisation route with potential to replace oil-based plastics, simultaneously bringing filler-containing cellulose waste into circular economy. To exemplify, composite cellulose-CaCO3 filaments were produced from cellulose pulp and waste office paper (already containing 27 w/w% precipitated CaCO3filler), without any pretreatment, using diazabicyclo[4.3.0]non-5-enium-acetate ([DHBN][OAc]) as IL solvent to form a dope. The dope suspension was extruded via dry-jet wet spinning. Surface morphology and elemental analysis were investigated using scanning electron microscopy with energy dispersive X-ray spectroscopy. X-ray diffraction was used to measure the degree of cellulose crystallinity. Static and dynamic mechanical properties were determined. Thermal stability was evaluated by thermogravimetric analysis. Filaments obtained from waste office paper showed that high filler levels and the presence of print toner enhanced both mechanical and thermal stability, while decreasing, as expected, ultimate breaking strength in comparison to filaments containing virgin cellulose alone. For comparison, 2 w/w% ground CaCO3 introduced into pure cellulose dope led to significant increase in cellulose crystallinity and resulting stiffness, while thermal properties remained unchanged at the low level filler addition. Such addition of CaCO3 during cellulose regeneration, or usage of already filled paper, could be an effective way to obtain high strength cellulose-CaCO3 composite materials, thus valorising in a circular economy renewable cellulosic wastes rejected from the current recycling stream.
PB  - Springer Science and Business Media B.V.
T2  - Cellulose
T1  - Extending waste paper, cellulose and filler use beyond recycling by entering the circular economy creating cellulose-CaCO3 composites reconstituted from ionic liquid
DO  - 10.1007/s10570-022-04575-w
ER  - 

@article{
author = "Kostić, Mirjana and Imani, Monireh and Ivanovska, Aleksandra and Radojević, Vesna and Dimić-Mišić, Katarina and Barać, Nemanja and Stojanović, Dušica and Janaćković, Đorđe and Uskoković, Petar and Barcelo, Ernest and Gane, Patrick",
year = "2022",
abstract = "Cellulose-fibre lifecycle is severely limited within today’s recycling methodology. Feedstock cellulose and filler abound in products considered uneconomic, unsuitable for standard deinking or too weak for original product re-use. Regeneration of cellulose from ionic liquid (IL) solution offers a novel valorisation route with potential to replace oil-based plastics, simultaneously bringing filler-containing cellulose waste into circular economy. To exemplify, composite cellulose-CaCO3 filaments were produced from cellulose pulp and waste office paper (already containing 27 w/w% precipitated CaCO3filler), without any pretreatment, using diazabicyclo[4.3.0]non-5-enium-acetate ([DHBN][OAc]) as IL solvent to form a dope. The dope suspension was extruded via dry-jet wet spinning. Surface morphology and elemental analysis were investigated using scanning electron microscopy with energy dispersive X-ray spectroscopy. X-ray diffraction was used to measure the degree of cellulose crystallinity. Static and dynamic mechanical properties were determined. Thermal stability was evaluated by thermogravimetric analysis. Filaments obtained from waste office paper showed that high filler levels and the presence of print toner enhanced both mechanical and thermal stability, while decreasing, as expected, ultimate breaking strength in comparison to filaments containing virgin cellulose alone. For comparison, 2 w/w% ground CaCO3 introduced into pure cellulose dope led to significant increase in cellulose crystallinity and resulting stiffness, while thermal properties remained unchanged at the low level filler addition. Such addition of CaCO3 during cellulose regeneration, or usage of already filled paper, could be an effective way to obtain high strength cellulose-CaCO3 composite materials, thus valorising in a circular economy renewable cellulosic wastes rejected from the current recycling stream.",
publisher = "Springer Science and Business Media B.V.",
journal = "Cellulose",
title = "Extending waste paper, cellulose and filler use beyond recycling by entering the circular economy creating cellulose-CaCO3 composites reconstituted from ionic liquid",
doi = "10.1007/s10570-022-04575-w"
}

Kostić, M., Imani, M., Ivanovska, A., Radojević, V., Dimić-Mišić, K., Barać, N., Stojanović, D., Janaćković, Đ., Uskoković, P., Barcelo, E.,& Gane, P.. (2022). Extending waste paper, cellulose and filler use beyond recycling by entering the circular economy creating cellulose-CaCO3 composites reconstituted from ionic liquid. in Cellulose
Springer Science and Business Media B.V...
https://doi.org/10.1007/s10570-022-04575-w

Kostić M, Imani M, Ivanovska A, Radojević V, Dimić-Mišić K, Barać N, Stojanović D, Janaćković Đ, Uskoković P, Barcelo E, Gane P. Extending waste paper, cellulose and filler use beyond recycling by entering the circular economy creating cellulose-CaCO3 composites reconstituted from ionic liquid. in Cellulose. 2022;.
doi:10.1007/s10570-022-04575-w .

Kostić, Mirjana, Imani, Monireh, Ivanovska, Aleksandra, Radojević, Vesna, Dimić-Mišić, Katarina, Barać, Nemanja, Stojanović, Dušica, Janaćković, Đorđe, Uskoković, Petar, Barcelo, Ernest, Gane, Patrick, "Extending waste paper, cellulose and filler use beyond recycling by entering the circular economy creating cellulose-CaCO3 composites reconstituted from ionic liquid" in Cellulose (2022),
https://doi.org/10.1007/s10570-022-04575-w . .

TY  - JOUR
AU  - Obradović, Vera
AU  - Vuksanović, Marija M.
AU  - Tomić, Nataša
AU  - Petrović, Miloš
AU  - Marinković, Aleksandar
AU  - Stojanović, Dušica
AU  - Radojević, Vesna
AU  - Jančić-Heinemann, Radmila
AU  - Uskoković, Petar
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5167
AB  - This study presents the impact properties of the new form of hybrid thermoplastic composites. The Kolon fabrics were impregnated with the 10 wt% poly (vinyl butyral) (PVB)/ethanol solution with the addition of silica (SiO2) particles originating from rice husk or layered double hydroxide modified silica particles (FeAl-LDH@SiO2) as reinforcement. All the composites consisted of one layer of the impregnated fabric where the silica particles concentrations were 0.5 wt% and 1.0 wt% regarding PVB. The impact properties of the composite samples were analyzed by the controlled energy puncture impact tester. The structures of the composite samples were determined by the attenuated total reflection Fourier-transform infrared spectroscopy (ATR-FTIR) and field emission scanning electron microscopy (FE-SEM). The results showed that the Kolon/PVB/1 wt% FeAl-LDH@SiO2 sample yielded the maximum impact force.
T2  - Materials Letters
T1  - Impact properties of Kolon/PVB fabrics reinforced with rice-husk silica particles
SP  - 132668
VL  - 324
DO  - 10.1016/j.matlet.2022.132668
ER  - 

@article{
author = "Obradović, Vera and Vuksanović, Marija M. and Tomić, Nataša and Petrović, Miloš and Marinković, Aleksandar and Stojanović, Dušica and Radojević, Vesna and Jančić-Heinemann, Radmila and Uskoković, Petar",
year = "2022",
abstract = "This study presents the impact properties of the new form of hybrid thermoplastic composites. The Kolon fabrics were impregnated with the 10 wt% poly (vinyl butyral) (PVB)/ethanol solution with the addition of silica (SiO2) particles originating from rice husk or layered double hydroxide modified silica particles (FeAl-LDH@SiO2) as reinforcement. All the composites consisted of one layer of the impregnated fabric where the silica particles concentrations were 0.5 wt% and 1.0 wt% regarding PVB. The impact properties of the composite samples were analyzed by the controlled energy puncture impact tester. The structures of the composite samples were determined by the attenuated total reflection Fourier-transform infrared spectroscopy (ATR-FTIR) and field emission scanning electron microscopy (FE-SEM). The results showed that the Kolon/PVB/1 wt% FeAl-LDH@SiO2 sample yielded the maximum impact force.",
journal = "Materials Letters",
title = "Impact properties of Kolon/PVB fabrics reinforced with rice-husk silica particles",
pages = "132668",
volume = "324",
doi = "10.1016/j.matlet.2022.132668"
}

Obradović, V., Vuksanović, M. M., Tomić, N., Petrović, M., Marinković, A., Stojanović, D., Radojević, V., Jančić-Heinemann, R.,& Uskoković, P.. (2022). Impact properties of Kolon/PVB fabrics reinforced with rice-husk silica particles. in Materials Letters, 324, 132668.
https://doi.org/10.1016/j.matlet.2022.132668

Obradović V, Vuksanović MM, Tomić N, Petrović M, Marinković A, Stojanović D, Radojević V, Jančić-Heinemann R, Uskoković P. Impact properties of Kolon/PVB fabrics reinforced with rice-husk silica particles. in Materials Letters. 2022;324:132668.
doi:10.1016/j.matlet.2022.132668 .

Obradović, Vera, Vuksanović, Marija M., Tomić, Nataša, Petrović, Miloš, Marinković, Aleksandar, Stojanović, Dušica, Radojević, Vesna, Jančić-Heinemann, Radmila, Uskoković, Petar, "Impact properties of Kolon/PVB fabrics reinforced with rice-husk silica particles" in Materials Letters, 324 (2022):132668,
https://doi.org/10.1016/j.matlet.2022.132668 . .

TY  - CONF
AU  - Nowak, Mariusz
AU  - Semba, Damian
AU  - Mišić, Dušan
AU  - Półbrat, Tomasz
AU  - Stojanović, Dušica
AU  - Trusek, Anna
AU  - Žižović, Irena
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6937
AB  - There is an urgency to develop novel materials capable of preventing the adherence of microorganisms to
their surface. Such materials with antibiofilm properties are needed in hospitals and public places, animal
farms and veterinary hospitals, and biofouling prevention. Biofouling is the phenomenon of adhesion and
the growth of microorganisms on surfaces in contact with water. It poses a significant problem for filtration
processes, water treatment units, bioreactors, and ships performance (marine biofouling). High-pressure
techniques such as supercritical solvent impregnation and grafting in the supercritical phase allow for the
modification of a solid matrix throughout the whole volume and production of materials of unique
properties in an environmentally friendly way. Grafting involves the chemical attachment of an active
compound to a solid matrix, ensuring its long-lasting properties. Grafting in supercritical carbon dioxide
(scCO2) has been reported as an efficient tool in the production of materials with antibacterial1
, and recently
also antibiofilm properties2
. This study aims to investigate the potential of cellulose acetate (CA) grafting
with quaternary ammonium compounds (QAC) for acquiring antibiofilm properties. Two QAC were
synthesized, and the grafting conditions were investigated. The grafting was performed via hexamethylene
diisocyanate (HDI) as a linker1
. Obtained materials were analyzed using FTIR, SEM and Ion microscopy,
DSC analyses, contact angle measurements, and standardized microbiological procedures to evaluate
antibiofilm properties.
C3  - 13th International Symposium on Supercritical Fluids Montreal, ISSF2022, Canada, May 15-18, 2022
T1  - Cellulose Acetate Modification Towards Antibiofilm Properties via Chemical Attachment of Quaternary Ammonium Compounds using Supercritical CO2
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6937
ER  - 

@conference{
author = "Nowak, Mariusz and Semba, Damian and Mišić, Dušan and Półbrat, Tomasz and Stojanović, Dušica and Trusek, Anna and Žižović, Irena",
year = "2022",
abstract = "There is an urgency to develop novel materials capable of preventing the adherence of microorganisms to
their surface. Such materials with antibiofilm properties are needed in hospitals and public places, animal
farms and veterinary hospitals, and biofouling prevention. Biofouling is the phenomenon of adhesion and
the growth of microorganisms on surfaces in contact with water. It poses a significant problem for filtration
processes, water treatment units, bioreactors, and ships performance (marine biofouling). High-pressure
techniques such as supercritical solvent impregnation and grafting in the supercritical phase allow for the
modification of a solid matrix throughout the whole volume and production of materials of unique
properties in an environmentally friendly way. Grafting involves the chemical attachment of an active
compound to a solid matrix, ensuring its long-lasting properties. Grafting in supercritical carbon dioxide
(scCO2) has been reported as an efficient tool in the production of materials with antibacterial1
, and recently
also antibiofilm properties2
. This study aims to investigate the potential of cellulose acetate (CA) grafting
with quaternary ammonium compounds (QAC) for acquiring antibiofilm properties. Two QAC were
synthesized, and the grafting conditions were investigated. The grafting was performed via hexamethylene
diisocyanate (HDI) as a linker1
. Obtained materials were analyzed using FTIR, SEM and Ion microscopy,
DSC analyses, contact angle measurements, and standardized microbiological procedures to evaluate
antibiofilm properties.",
journal = "13th International Symposium on Supercritical Fluids Montreal, ISSF2022, Canada, May 15-18, 2022",
title = "Cellulose Acetate Modification Towards Antibiofilm Properties via Chemical Attachment of Quaternary Ammonium Compounds using Supercritical CO2",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6937"
}

Nowak, M., Semba, D., Mišić, D., Półbrat, T., Stojanović, D., Trusek, A.,& Žižović, I.. (2022). Cellulose Acetate Modification Towards Antibiofilm Properties via Chemical Attachment of Quaternary Ammonium Compounds using Supercritical CO2. in 13th International Symposium on Supercritical Fluids Montreal, ISSF2022, Canada, May 15-18, 2022.
https://hdl.handle.net/21.15107/rcub_technorep_6937

Nowak M, Semba D, Mišić D, Półbrat T, Stojanović D, Trusek A, Žižović I. Cellulose Acetate Modification Towards Antibiofilm Properties via Chemical Attachment of Quaternary Ammonium Compounds using Supercritical CO2. in 13th International Symposium on Supercritical Fluids Montreal, ISSF2022, Canada, May 15-18, 2022. 2022;.
https://hdl.handle.net/21.15107/rcub_technorep_6937 .

Nowak, Mariusz, Semba, Damian, Mišić, Dušan, Półbrat, Tomasz, Stojanović, Dušica, Trusek, Anna, Žižović, Irena, "Cellulose Acetate Modification Towards Antibiofilm Properties via Chemical Attachment of Quaternary Ammonium Compounds using Supercritical CO2" in 13th International Symposium on Supercritical Fluids Montreal, ISSF2022, Canada, May 15-18, 2022 (2022),
https://hdl.handle.net/21.15107/rcub_technorep_6937 .

TY  - JOUR
AU  - Mirković, Mihailo
AU  - Stojanović, Dušica B.
AU  - Mijailović, Daniel
AU  - Barać, Nemanja
AU  - Janaćković, Đorđe
AU  - Uskoković, Petar S.
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5112
AB  - Particulate matter 2.5 (PM2.5) pollutant particles have been identified as significant participants in air pollution, thus, special attention is paid to air filtration as a method of their efficient removal. A novel and simple method of producing nanofiber-based filters for efficient PM2.5 capture with multiple active components are proposed. Electrospun polyacrylonitrile (PAN) polymer was used both as a base filter material and as a precursor for producing microporous carbon nanofibers (MCNFs), which incorporated into the nanofibrous structure of the filter media. The fabricated PAN/MCNFs filters could reach removal efficiency of PM2.5 pollutant particles of up to 99% for with polluted air airflow velocity of 500 ml min−1, showing greater pollutant particle binding affinity with incorporated MCNFs. Experiments also show enhanced mechanical and thermal properties of studied air filters, with the addition of MCNFs – more than 4% and 6% increase in storage modulus and cyclization temperature in comparison to the base PAN filter, respectively. While using a facemask with inserted PAN/MCNFs filter, a reduced temperature variation in the facial region of the user was recorded – several degrees less when compared to a commonly used 3 M Aura 9320+ mask. This opens a possibility of their application in both industrial air filtering and as filters in facemask production.
PB  - Elsevier Ltd
T2  - Materials Chemistry and Physics
T1  - Electrospun polyacrylonitrile fibers incorporated with microporous carbon for improved airborne PM2.5 filtration
SP  - 126103
VL  - 285
DO  - 10.1016/j.matchemphys.2022.126103
ER  - 

@article{
author = "Mirković, Mihailo and Stojanović, Dušica B. and Mijailović, Daniel and Barać, Nemanja and Janaćković, Đorđe and Uskoković, Petar S.",
year = "2022",
abstract = "Particulate matter 2.5 (PM2.5) pollutant particles have been identified as significant participants in air pollution, thus, special attention is paid to air filtration as a method of their efficient removal. A novel and simple method of producing nanofiber-based filters for efficient PM2.5 capture with multiple active components are proposed. Electrospun polyacrylonitrile (PAN) polymer was used both as a base filter material and as a precursor for producing microporous carbon nanofibers (MCNFs), which incorporated into the nanofibrous structure of the filter media. The fabricated PAN/MCNFs filters could reach removal efficiency of PM2.5 pollutant particles of up to 99% for with polluted air airflow velocity of 500 ml min−1, showing greater pollutant particle binding affinity with incorporated MCNFs. Experiments also show enhanced mechanical and thermal properties of studied air filters, with the addition of MCNFs – more than 4% and 6% increase in storage modulus and cyclization temperature in comparison to the base PAN filter, respectively. While using a facemask with inserted PAN/MCNFs filter, a reduced temperature variation in the facial region of the user was recorded – several degrees less when compared to a commonly used 3 M Aura 9320+ mask. This opens a possibility of their application in both industrial air filtering and as filters in facemask production.",
publisher = "Elsevier Ltd",
journal = "Materials Chemistry and Physics",
title = "Electrospun polyacrylonitrile fibers incorporated with microporous carbon for improved airborne PM2.5 filtration",
pages = "126103",
volume = "285",
doi = "10.1016/j.matchemphys.2022.126103"
}

Mirković, M., Stojanović, D. B., Mijailović, D., Barać, N., Janaćković, Đ.,& Uskoković, P. S.. (2022). Electrospun polyacrylonitrile fibers incorporated with microporous carbon for improved airborne PM2.5 filtration. in Materials Chemistry and Physics
Elsevier Ltd., 285, 126103.
https://doi.org/10.1016/j.matchemphys.2022.126103

Mirković M, Stojanović DB, Mijailović D, Barać N, Janaćković Đ, Uskoković PS. Electrospun polyacrylonitrile fibers incorporated with microporous carbon for improved airborne PM2.5 filtration. in Materials Chemistry and Physics. 2022;285:126103.
doi:10.1016/j.matchemphys.2022.126103 .

Mirković, Mihailo, Stojanović, Dušica B., Mijailović, Daniel, Barać, Nemanja, Janaćković, Đorđe, Uskoković, Petar S., "Electrospun polyacrylonitrile fibers incorporated with microporous carbon for improved airborne PM2.5 filtration" in Materials Chemistry and Physics, 285 (2022):126103,
https://doi.org/10.1016/j.matchemphys.2022.126103 . .

TY  - JOUR
AU  - Jovanović, Marija
AU  - Petrović, Miloš
AU  - Stojanović, Dušica
AU  - Ibrić, Svetlana
AU  - Uskoković, Petar
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5961
AB  - In this work, a blend of gelatin A (GA) and polyvinylpyrrolidone (PVP K30) was used for semi-solid 3D printing of bone scaffold for ibuprofen (IBU) delivery. The cross-linking of the obtained scaffold was performed with a 1% glutaraldehyde (GTA) solution, followed by lyophilization. The thermal and mechanical properties, as well as drug release profiles, and drug kinetics of prepared scaffolds were investigated. The cross-linked and lyophilized scaffold has shown good thermal stability, mechanical properties, and prolonged release of IBU following the Fickian diffusion process.
PB  - Savez farmaceutskih udruženja Srbije
T2  - Arhiv za Farmaciju
T1  - Preparation and characterization of 3D printed bone scaffold for ibuprofen delivery
T1  - 3D štampa i karakterizacija nosača za dostavu ibuprofena u koštanom tkivu
EP  - 673
IS  - 6
SP  - 661
VL  - 72
DO  - 10.5937/ARHFARM72-40262
ER  - 

@article{
author = "Jovanović, Marija and Petrović, Miloš and Stojanović, Dušica and Ibrić, Svetlana and Uskoković, Petar",
year = "2022",
abstract = "In this work, a blend of gelatin A (GA) and polyvinylpyrrolidone (PVP K30) was used for semi-solid 3D printing of bone scaffold for ibuprofen (IBU) delivery. The cross-linking of the obtained scaffold was performed with a 1% glutaraldehyde (GTA) solution, followed by lyophilization. The thermal and mechanical properties, as well as drug release profiles, and drug kinetics of prepared scaffolds were investigated. The cross-linked and lyophilized scaffold has shown good thermal stability, mechanical properties, and prolonged release of IBU following the Fickian diffusion process.",
publisher = "Savez farmaceutskih udruženja Srbije",
journal = "Arhiv za Farmaciju",
title = "Preparation and characterization of 3D printed bone scaffold for ibuprofen delivery, 3D štampa i karakterizacija nosača za dostavu ibuprofena u koštanom tkivu",
pages = "673-661",
number = "6",
volume = "72",
doi = "10.5937/ARHFARM72-40262"
}

Jovanović, M., Petrović, M., Stojanović, D., Ibrić, S.,& Uskoković, P.. (2022). Preparation and characterization of 3D printed bone scaffold for ibuprofen delivery. in Arhiv za Farmaciju
Savez farmaceutskih udruženja Srbije., 72(6), 661-673.
https://doi.org/10.5937/ARHFARM72-40262

Jovanović M, Petrović M, Stojanović D, Ibrić S, Uskoković P. Preparation and characterization of 3D printed bone scaffold for ibuprofen delivery. in Arhiv za Farmaciju. 2022;72(6):661-673.
doi:10.5937/ARHFARM72-40262 .

Jovanović, Marija, Petrović, Miloš, Stojanović, Dušica, Ibrić, Svetlana, Uskoković, Petar, "Preparation and characterization of 3D printed bone scaffold for ibuprofen delivery" in Arhiv za Farmaciju, 72, no. 6 (2022):661-673,
https://doi.org/10.5937/ARHFARM72-40262 . .

TY  - JOUR
AU  - Barać, Nemanja
AU  - Barcelo, Ernest
AU  - Stojanović, Dušica
AU  - Milovanović, Stoja
AU  - Uskoković, Petar
AU  - Gane, Patrick
AU  - Dimic-Misic, Katarina
AU  - Imani, Monireh
AU  - Janaćković, Đorđe
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5007
AB  - In this work, we examine two modifications of fine-ground calcium carbonate material (GCC) in order to enhanced sorption of NO2 and subsequent reaction properties toward NO2-/NO3- formation by firstly exposing the GCC to supercritical (sc) CO2 in order to increase particle surface area, a choice specifically made to avoid altering the surface chemistry, and secondly considering the potential advantage of using a surface coupling agent toward NO2. The modification by the coupling agent amino silane (AMEO silane) was applied in a supercritical CO2-ethanol mixture. The samples were characterised before and after modification by field emission scanning electron microscopy (FESEM), specific surface area determination (BET nitrogen adsorption), ATR-FTIR spectroscopy and ion chromatography to reveal the effects of the surface modification(s) on the morphology, surface textural properties and sorption versus reaction properties with NO2. The performance of the treated sorbents for NO2 capture was evaluated at room temperature. Results show that reactivity of NO2 with GCC was observed to increase as a function of increased surface area resulting from scCO(2) exposure, but that the presence of AMEO silane on the surface, while enhancing initial adsorption of NO2 was seen subsequently to act to block reactivity. Thus, judicious use of coupling agent can provide desired rapid initial adsorption of the gas, but the goal of long-term CaCO3-consuming reactivity, so as to prolong the uptake of NO2 beyond surface saturation alone, is achieved by increasing surface area while retaining chemical-free exposed CaCO3 surface.
T2  - Environmental Science and Pollution Research
T1  - Modification of CaCO3 and CaCO3 pin-coated cellulose paper under supercritical carbon dioxide-ethanol mixture for enhanced NO2 capture
EP  - 11717
IS  - 8
SP  - 11707
VL  - 29
DO  - 10.1007/s11356-021-16503-9
ER  - 

@article{
author = "Barać, Nemanja and Barcelo, Ernest and Stojanović, Dušica and Milovanović, Stoja and Uskoković, Petar and Gane, Patrick and Dimic-Misic, Katarina and Imani, Monireh and Janaćković, Đorđe",
year = "2022",
abstract = "In this work, we examine two modifications of fine-ground calcium carbonate material (GCC) in order to enhanced sorption of NO2 and subsequent reaction properties toward NO2-/NO3- formation by firstly exposing the GCC to supercritical (sc) CO2 in order to increase particle surface area, a choice specifically made to avoid altering the surface chemistry, and secondly considering the potential advantage of using a surface coupling agent toward NO2. The modification by the coupling agent amino silane (AMEO silane) was applied in a supercritical CO2-ethanol mixture. The samples were characterised before and after modification by field emission scanning electron microscopy (FESEM), specific surface area determination (BET nitrogen adsorption), ATR-FTIR spectroscopy and ion chromatography to reveal the effects of the surface modification(s) on the morphology, surface textural properties and sorption versus reaction properties with NO2. The performance of the treated sorbents for NO2 capture was evaluated at room temperature. Results show that reactivity of NO2 with GCC was observed to increase as a function of increased surface area resulting from scCO(2) exposure, but that the presence of AMEO silane on the surface, while enhancing initial adsorption of NO2 was seen subsequently to act to block reactivity. Thus, judicious use of coupling agent can provide desired rapid initial adsorption of the gas, but the goal of long-term CaCO3-consuming reactivity, so as to prolong the uptake of NO2 beyond surface saturation alone, is achieved by increasing surface area while retaining chemical-free exposed CaCO3 surface.",
journal = "Environmental Science and Pollution Research",
title = "Modification of CaCO3 and CaCO3 pin-coated cellulose paper under supercritical carbon dioxide-ethanol mixture for enhanced NO2 capture",
pages = "11717-11707",
number = "8",
volume = "29",
doi = "10.1007/s11356-021-16503-9"
}

Barać, N., Barcelo, E., Stojanović, D., Milovanović, S., Uskoković, P., Gane, P., Dimic-Misic, K., Imani, M.,& Janaćković, Đ.. (2022). Modification of CaCO3 and CaCO3 pin-coated cellulose paper under supercritical carbon dioxide-ethanol mixture for enhanced NO2 capture. in Environmental Science and Pollution Research, 29(8), 11707-11717.
https://doi.org/10.1007/s11356-021-16503-9

Barać N, Barcelo E, Stojanović D, Milovanović S, Uskoković P, Gane P, Dimic-Misic K, Imani M, Janaćković Đ. Modification of CaCO3 and CaCO3 pin-coated cellulose paper under supercritical carbon dioxide-ethanol mixture for enhanced NO2 capture. in Environmental Science and Pollution Research. 2022;29(8):11707-11717.
doi:10.1007/s11356-021-16503-9 .

Barać, Nemanja, Barcelo, Ernest, Stojanović, Dušica, Milovanović, Stoja, Uskoković, Petar, Gane, Patrick, Dimic-Misic, Katarina, Imani, Monireh, Janaćković, Đorđe, "Modification of CaCO3 and CaCO3 pin-coated cellulose paper under supercritical carbon dioxide-ethanol mixture for enhanced NO2 capture" in Environmental Science and Pollution Research, 29, no. 8 (2022):11707-11717,
https://doi.org/10.1007/s11356-021-16503-9 . .

Obradović, V., Vuksanović, M., Tomić, N., Petrović, M., Marinković, A., Radojević, V., Jančić Heinemann, R., Stojanović, D.,& Uskoković, P.. (2021). Primena čestica silicijum dioksida dobijenog iz biomase za ojačanje aramidnih kompozita otpornih na udar. .
https://hdl.handle.net/21.15107/rcub_technorep_7067

Obradović V, Vuksanović M, Tomić N, Petrović M, Marinković A, Radojević V, Jančić Heinemann R, Stojanović D, Uskoković P. Primena čestica silicijum dioksida dobijenog iz biomase za ojačanje aramidnih kompozita otpornih na udar. 2021;.
https://hdl.handle.net/21.15107/rcub_technorep_7067 .

Obradović, Vera, Vuksanović, Marija, Tomić, Nataša, Petrović, Miloš, Marinković, Aleksandar, Radojević, Vesna, Jančić Heinemann, Radmila, Stojanović, Dušica, Uskoković, Petar, "Primena čestica silicijum dioksida dobijenog iz biomase za ojačanje aramidnih kompozita otpornih na udar" (2021),
https://hdl.handle.net/21.15107/rcub_technorep_7067 .

TY  - CONF
AU  - Mirković, Mihailo
AU  - Stojanović, Dušica
AU  - Mijailović, Daniel
AU  - Barać, Nemanja
AU  - Janaćković, Đorđe
AU  - Uskoković, Petar
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6681
AB  - Air pollution is often related to increased concentration of particulate matter 2.5 (PM2.5)
pollutant particles in the air. One of the methods of their removal is air filtration. Hereby, a
novel and simple method of producing nanofiber-based air filters with multiple active
components for highly efficient PM2.5 capture is proposed. Micro-porous carbon nanofibers
(MCNFs) were produced by carbonizing electrospun polyacrylonitrile (PAN) polymer and
was later incorporated into the nanofibrous structure of the filters, which itself was made
from electrospun PAN, achieving the production of two active components of the filter from
one starting material, simplifying the production process. When compared to the base PAN
filter, PAN/MCNFs filter exhibits greater filtering properties with almost absolute pollutant
particle removal. Their improved thermal and mechanical properties make this kind of filters
suitable for harsh-condition environments, such as those in industrial plants. The possibility
of using studied filters in facemask production was studied and reduced temperature
variation was recorded when using a facemask with an inserted PAN/MCNFs filter, thus
increasing wearing comfort for the user. All mentioned properties open a potential possibility
for these filters to be used in different environments, but also leave room for further
improvement.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Program and the Book of abstracts / Nineteenth Young Researchers' Conference Materials Science and Engineering, December 1-3, 2021, Belgrade, Serbia
T1  - Novel PAN-based Air Filters for Potential Applications in Industrial Air Filtering and Facemask Production
SP  - 61
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6681
ER  - 

@conference{
author = "Mirković, Mihailo and Stojanović, Dušica and Mijailović, Daniel and Barać, Nemanja and Janaćković, Đorđe and Uskoković, Petar",
year = "2021",
abstract = "Air pollution is often related to increased concentration of particulate matter 2.5 (PM2.5)
pollutant particles in the air. One of the methods of their removal is air filtration. Hereby, a
novel and simple method of producing nanofiber-based air filters with multiple active
components for highly efficient PM2.5 capture is proposed. Micro-porous carbon nanofibers
(MCNFs) were produced by carbonizing electrospun polyacrylonitrile (PAN) polymer and
was later incorporated into the nanofibrous structure of the filters, which itself was made
from electrospun PAN, achieving the production of two active components of the filter from
one starting material, simplifying the production process. When compared to the base PAN
filter, PAN/MCNFs filter exhibits greater filtering properties with almost absolute pollutant
particle removal. Their improved thermal and mechanical properties make this kind of filters
suitable for harsh-condition environments, such as those in industrial plants. The possibility
of using studied filters in facemask production was studied and reduced temperature
variation was recorded when using a facemask with an inserted PAN/MCNFs filter, thus
increasing wearing comfort for the user. All mentioned properties open a potential possibility
for these filters to be used in different environments, but also leave room for further
improvement.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Program and the Book of abstracts / Nineteenth Young Researchers' Conference Materials Science and Engineering, December 1-3, 2021, Belgrade, Serbia",
title = "Novel PAN-based Air Filters for Potential Applications in Industrial Air Filtering and Facemask Production",
pages = "61",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6681"
}

Mirković, M., Stojanović, D., Mijailović, D., Barać, N., Janaćković, Đ.,& Uskoković, P.. (2021). Novel PAN-based Air Filters for Potential Applications in Industrial Air Filtering and Facemask Production. in Program and the Book of abstracts / Nineteenth Young Researchers' Conference Materials Science and Engineering, December 1-3, 2021, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA., 61.
https://hdl.handle.net/21.15107/rcub_technorep_6681

Mirković M, Stojanović D, Mijailović D, Barać N, Janaćković Đ, Uskoković P. Novel PAN-based Air Filters for Potential Applications in Industrial Air Filtering and Facemask Production. in Program and the Book of abstracts / Nineteenth Young Researchers' Conference Materials Science and Engineering, December 1-3, 2021, Belgrade, Serbia. 2021;:61.
https://hdl.handle.net/21.15107/rcub_technorep_6681 .

Mirković, Mihailo, Stojanović, Dušica, Mijailović, Daniel, Barać, Nemanja, Janaćković, Đorđe, Uskoković, Petar, "Novel PAN-based Air Filters for Potential Applications in Industrial Air Filtering and Facemask Production" in Program and the Book of abstracts / Nineteenth Young Researchers' Conference Materials Science and Engineering, December 1-3, 2021, Belgrade, Serbia (2021):61,
https://hdl.handle.net/21.15107/rcub_technorep_6681 .

TY  - CONF
AU  - Bajić, Danica M.
AU  - Fidanovski, Bojana
AU  - Radisavljević, Igor
AU  - Bogosavljević, Marica
AU  - Totovski, Ljubica
AU  - Stojanović, Dušica B.
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6933
AB  - As one of transition metal dichalogenides, tungsten disulphide (WS2) is well known for its solid
lubricating behavior, but besides this feature, it exhibits extraordinary thermal stability and mechanical
resistance. The outstanding mechanical strength of WS2 is most pronounced when it comes in form of
multi-layer hollow nanoparticles and nanotubes: inorganic fullerene-like nanoparticles and inorganic
nanotubes, denoted as IF-WS2 and INT-WS2, respectively. These structures have extraordinary shock resistance
properties, pressure and heat resistance, that can be exploited for a variety of applications. They have been
studied as reinforcing fillers of various polymers, but they might be also added as reinforcement of matrix in
more complex composites, like CFRPs. Our research aimed to examine their reinforcing effect on laminated
composites based on aramid fabric and poly(vinyl butyral), PVB, intended for demanding applications: in
personal protection equipment, ballistic protection, sports equipment, automotive, nautical and aircraft
engineering. WS2 nanostructures have been incorporated in PVB by temporary dissolving in ethanol, by
ultrasonication and intensive mechanical mixing. After impregnation of aramid fabrics ethanol would
evaporate, and layers of aramid with thermoplastic binder PVB would be integrated by hot pressing. SEM
analysis confirms the uniform distribution of WS2 nanostructures in the prepared composite material. DSC
analysis reveals the effect of WS2 addition on thermal resistance of the new material, while PVB/aramid
mechanical resistance was examined using DMA, impact test and tensile test. IF- WS2 has imported higher
thermal resistance and ductility improvement, while INT-WS2 has significantly improved tensile and impact
strength of the composite.
C3  - Abstract Book / 3 rd Edition of Materials Science and Nanoscience Webinar, V-Mat2021, September 17-18, 2021
T1  - WS2 nanostructures as thermo-mechanical reinforcement of composite materials for advanced applications
SP  - 40
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6933
ER  - 

@conference{
author = "Bajić, Danica M. and Fidanovski, Bojana and Radisavljević, Igor and Bogosavljević, Marica and Totovski, Ljubica and Stojanović, Dušica B.",
year = "2021",
abstract = "As one of transition metal dichalogenides, tungsten disulphide (WS2) is well known for its solid
lubricating behavior, but besides this feature, it exhibits extraordinary thermal stability and mechanical
resistance. The outstanding mechanical strength of WS2 is most pronounced when it comes in form of
multi-layer hollow nanoparticles and nanotubes: inorganic fullerene-like nanoparticles and inorganic
nanotubes, denoted as IF-WS2 and INT-WS2, respectively. These structures have extraordinary shock resistance
properties, pressure and heat resistance, that can be exploited for a variety of applications. They have been
studied as reinforcing fillers of various polymers, but they might be also added as reinforcement of matrix in
more complex composites, like CFRPs. Our research aimed to examine their reinforcing effect on laminated
composites based on aramid fabric and poly(vinyl butyral), PVB, intended for demanding applications: in
personal protection equipment, ballistic protection, sports equipment, automotive, nautical and aircraft
engineering. WS2 nanostructures have been incorporated in PVB by temporary dissolving in ethanol, by
ultrasonication and intensive mechanical mixing. After impregnation of aramid fabrics ethanol would
evaporate, and layers of aramid with thermoplastic binder PVB would be integrated by hot pressing. SEM
analysis confirms the uniform distribution of WS2 nanostructures in the prepared composite material. DSC
analysis reveals the effect of WS2 addition on thermal resistance of the new material, while PVB/aramid
mechanical resistance was examined using DMA, impact test and tensile test. IF- WS2 has imported higher
thermal resistance and ductility improvement, while INT-WS2 has significantly improved tensile and impact
strength of the composite.",
journal = "Abstract Book / 3 rd Edition of Materials Science and Nanoscience Webinar, V-Mat2021, September 17-18, 2021",
title = "WS2 nanostructures as thermo-mechanical reinforcement of composite materials for advanced applications",
pages = "40",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6933"
}

Bajić, D. M., Fidanovski, B., Radisavljević, I., Bogosavljević, M., Totovski, L.,& Stojanović, D. B.. (2021). WS2 nanostructures as thermo-mechanical reinforcement of composite materials for advanced applications. in Abstract Book / 3 rd Edition of Materials Science and Nanoscience Webinar, V-Mat2021, September 17-18, 2021, 40.
https://hdl.handle.net/21.15107/rcub_technorep_6933

Bajić DM, Fidanovski B, Radisavljević I, Bogosavljević M, Totovski L, Stojanović DB. WS2 nanostructures as thermo-mechanical reinforcement of composite materials for advanced applications. in Abstract Book / 3 rd Edition of Materials Science and Nanoscience Webinar, V-Mat2021, September 17-18, 2021. 2021;:40.
https://hdl.handle.net/21.15107/rcub_technorep_6933 .

Bajić, Danica M., Fidanovski, Bojana, Radisavljević, Igor, Bogosavljević, Marica, Totovski, Ljubica, Stojanović, Dušica B., "WS2 nanostructures as thermo-mechanical reinforcement of composite materials for advanced applications" in Abstract Book / 3 rd Edition of Materials Science and Nanoscience Webinar, V-Mat2021, September 17-18, 2021 (2021):40,
https://hdl.handle.net/21.15107/rcub_technorep_6933 .

TY  - JOUR
AU  - Obradović, Vera
AU  - Vuksanović, Marija M.
AU  - Tomić, Nataša
AU  - Stojanović, Dušica
AU  - Volkov-Husović, Tatjana
AU  - Uskoković, Petar
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4954
AB  - In this study poly (vinyl butyral)/silica (PVB/SiO2) composite films were subjected to the cavitation process. The experiments were carried out with a 10 wt.% PVB solution in ethanol. Silica nanoparticles were added into the solution in different concentration of 1, 3 and 5 wt.% SiO2 in regard to PVB. Composite films were cast from these solutions and subjected to ultrasonic cavitation. Optical images of their surfaces were analyzed before and after cavitation, by Image-Pro Plus software. The results revealed that the PVB film with 5 wt.% SiO2 nanoparticles demonstrated the greatest improvement in microhardness with the best cavitation resistance compared to other films.
T2  - Polymers & Polymer Composites
T1  - Improvement in cavitation resistance of poly (vinyl butyral) composite films with silica nanoparticles: A technical note
EP  - S1669
IS  - 9_SUPPL
SP  - S1664
VL  - 29
DO  - 10.1177/0967391120986505
ER  - 

@article{
author = "Obradović, Vera and Vuksanović, Marija M. and Tomić, Nataša and Stojanović, Dušica and Volkov-Husović, Tatjana and Uskoković, Petar",
year = "2021",
abstract = "In this study poly (vinyl butyral)/silica (PVB/SiO2) composite films were subjected to the cavitation process. The experiments were carried out with a 10 wt.% PVB solution in ethanol. Silica nanoparticles were added into the solution in different concentration of 1, 3 and 5 wt.% SiO2 in regard to PVB. Composite films were cast from these solutions and subjected to ultrasonic cavitation. Optical images of their surfaces were analyzed before and after cavitation, by Image-Pro Plus software. The results revealed that the PVB film with 5 wt.% SiO2 nanoparticles demonstrated the greatest improvement in microhardness with the best cavitation resistance compared to other films.",
journal = "Polymers & Polymer Composites",
title = "Improvement in cavitation resistance of poly (vinyl butyral) composite films with silica nanoparticles: A technical note",
pages = "S1669-S1664",
number = "9_SUPPL",
volume = "29",
doi = "10.1177/0967391120986505"
}

Obradović, V., Vuksanović, M. M., Tomić, N., Stojanović, D., Volkov-Husović, T.,& Uskoković, P.. (2021). Improvement in cavitation resistance of poly (vinyl butyral) composite films with silica nanoparticles: A technical note. in Polymers & Polymer Composites, 29(9_SUPPL), S1664-S1669.
https://doi.org/10.1177/0967391120986505

Obradović V, Vuksanović MM, Tomić N, Stojanović D, Volkov-Husović T, Uskoković P. Improvement in cavitation resistance of poly (vinyl butyral) composite films with silica nanoparticles: A technical note. in Polymers & Polymer Composites. 2021;29(9_SUPPL):S1664-S1669.
doi:10.1177/0967391120986505 .

Obradović, Vera, Vuksanović, Marija M., Tomić, Nataša, Stojanović, Dušica, Volkov-Husović, Tatjana, Uskoković, Petar, "Improvement in cavitation resistance of poly (vinyl butyral) composite films with silica nanoparticles: A technical note" in Polymers & Polymer Composites, 29, no. 9_SUPPL (2021):S1664-S1669,
https://doi.org/10.1177/0967391120986505 . .

TY  - JOUR
AU  - Mijailović, Daniel
AU  - Radmilović, Vuk
AU  - Lačnjevac, Uroš C.
AU  - Stojanović, Dušica
AU  - Bustillo, Karen C.
AU  - Jović, Vladimir D.
AU  - Radmilović, Velimir R.
AU  - Uskoković, Petar
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4768
AB  - We herein report a simple two-step procedure for fabricating tetragonal CoMn2O4 spinel nanocrystals on carbon fibers. The battery-type behavior of these composite fibers arises from the redox activity of CoMn2O4 in an alkaline aqueous solution, which, in combination with the carbon fibers, endows good electrochemical performance and long-term stability. The C"CoMn2O4 electrode exhibited high specific capacity, up to 62 mA h g(-1) at 1 A g(-1) with a capacity retention of around 90% after 4000 cycles. A symmetrical coin-cell device assembled with the composite electrodes delivered a high energy density of 7.3 W h kg(-1) at a power density of 0.1 kW kg(-1), which is around 13 times higher than that of bare carbon electrodes. The coin cell was cycled for 5000 cycles with 96.3% capacitance retention, at a voltage of up to 0.8 V, demonstrating excellent cycling stability.
PB  - Royal Society of Chemistry
T2  - Dalton Transactions
T1  - Tetragonal CoMn2O4 nanocrystals on electrospun carbon fibers as high-performance battery-type supercapacitor electrode materials
EP  - 15678
IS  - 43
SP  - 15669
VL  - 50
DO  - 10.1039/d1dt02829d
ER  - 

@article{
author = "Mijailović, Daniel and Radmilović, Vuk and Lačnjevac, Uroš C. and Stojanović, Dušica and Bustillo, Karen C. and Jović, Vladimir D. and Radmilović, Velimir R. and Uskoković, Petar",
year = "2021",
abstract = "We herein report a simple two-step procedure for fabricating tetragonal CoMn2O4 spinel nanocrystals on carbon fibers. The battery-type behavior of these composite fibers arises from the redox activity of CoMn2O4 in an alkaline aqueous solution, which, in combination with the carbon fibers, endows good electrochemical performance and long-term stability. The C"CoMn2O4 electrode exhibited high specific capacity, up to 62 mA h g(-1) at 1 A g(-1) with a capacity retention of around 90% after 4000 cycles. A symmetrical coin-cell device assembled with the composite electrodes delivered a high energy density of 7.3 W h kg(-1) at a power density of 0.1 kW kg(-1), which is around 13 times higher than that of bare carbon electrodes. The coin cell was cycled for 5000 cycles with 96.3% capacitance retention, at a voltage of up to 0.8 V, demonstrating excellent cycling stability.",
publisher = "Royal Society of Chemistry",
journal = "Dalton Transactions",
title = "Tetragonal CoMn2O4 nanocrystals on electrospun carbon fibers as high-performance battery-type supercapacitor electrode materials",
pages = "15678-15669",
number = "43",
volume = "50",
doi = "10.1039/d1dt02829d"
}

Mijailović, D., Radmilović, V., Lačnjevac, U. C., Stojanović, D., Bustillo, K. C., Jović, V. D., Radmilović, V. R.,& Uskoković, P.. (2021). Tetragonal CoMn2O4 nanocrystals on electrospun carbon fibers as high-performance battery-type supercapacitor electrode materials. in Dalton Transactions
Royal Society of Chemistry., 50(43), 15669-15678.
https://doi.org/10.1039/d1dt02829d

Mijailović D, Radmilović V, Lačnjevac UC, Stojanović D, Bustillo KC, Jović VD, Radmilović VR, Uskoković P. Tetragonal CoMn2O4 nanocrystals on electrospun carbon fibers as high-performance battery-type supercapacitor electrode materials. in Dalton Transactions. 2021;50(43):15669-15678.
doi:10.1039/d1dt02829d .

Mijailović, Daniel, Radmilović, Vuk, Lačnjevac, Uroš C., Stojanović, Dušica, Bustillo, Karen C., Jović, Vladimir D., Radmilović, Velimir R., Uskoković, Petar, "Tetragonal CoMn2O4 nanocrystals on electrospun carbon fibers as high-performance battery-type supercapacitor electrode materials" in Dalton Transactions, 50, no. 43 (2021):15669-15678,
https://doi.org/10.1039/d1dt02829d . .

TY  - CONF
AU  - Jovanović, Marija N.
AU  - Radisavljević, Anđela N.
AU  - Petrović, Miloš M.
AU  - Stojanović, Dušica B.
AU  - Ibrić, Svetlana R.
AU  - Uskoković, Petar S.
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6078
AB  - The oral mucoadhesive film is a novel and attractive formulation for local and/or systemic drug
delivery through the mucosal membrane of the oral cavity. Certain active pharmaceutical ingredients (API) in conventional formulations (tablets, capsules, syrups) are absorbed in the gastrointestinal tract and undergo first-pass metabolism through the liver, thereby reducing their bioavailability. This problem can be overcome by using intraoral formulations, such as mucoadhesive buccal films that disintegrate and dissolve in the oral cavity where the absorption of API occurs. In this work, the mucoadhesive films were prepared by 3D paste printing and the influence of processing parameters on film properties and the release rate of a drug was investigated. Gelatin (GA) and the blend of gelatin/polyvinylpyrrolidone (GA/PVP) were used because of their biocompatibility. Propranolol hydrochloride (PRH) was used as a model substance because it has high first-pass metabolism and is soluble in water. Film morphology and drug distribution were followed by SEM analysis. Dissolution test in simulated saliva was done to see how PRH was released from films. Mucoadhesion test revealed that the GA/PVP films with PRH have the highest adhesion force. Obtained results introduce GA/PVP as a promising material with good adhesion and rate of drug release.
PB  - Belgrade : Materials Research Society of Serbia
C3  - Twenty-second Annual Conference YUCOMAT 2021, Herceg Novi, Montenegro
T1  - 3D printed mucoadhesive gelatin based buccal films
SP  - 122
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6078
ER  - 

@conference{
author = "Jovanović, Marija N. and Radisavljević, Anđela N. and Petrović, Miloš M. and Stojanović, Dušica B. and Ibrić, Svetlana R. and Uskoković, Petar S.",
year = "2021",
abstract = "The oral mucoadhesive film is a novel and attractive formulation for local and/or systemic drug
delivery through the mucosal membrane of the oral cavity. Certain active pharmaceutical ingredients (API) in conventional formulations (tablets, capsules, syrups) are absorbed in the gastrointestinal tract and undergo first-pass metabolism through the liver, thereby reducing their bioavailability. This problem can be overcome by using intraoral formulations, such as mucoadhesive buccal films that disintegrate and dissolve in the oral cavity where the absorption of API occurs. In this work, the mucoadhesive films were prepared by 3D paste printing and the influence of processing parameters on film properties and the release rate of a drug was investigated. Gelatin (GA) and the blend of gelatin/polyvinylpyrrolidone (GA/PVP) were used because of their biocompatibility. Propranolol hydrochloride (PRH) was used as a model substance because it has high first-pass metabolism and is soluble in water. Film morphology and drug distribution were followed by SEM analysis. Dissolution test in simulated saliva was done to see how PRH was released from films. Mucoadhesion test revealed that the GA/PVP films with PRH have the highest adhesion force. Obtained results introduce GA/PVP as a promising material with good adhesion and rate of drug release.",
publisher = "Belgrade : Materials Research Society of Serbia",
journal = "Twenty-second Annual Conference YUCOMAT 2021, Herceg Novi, Montenegro",
title = "3D printed mucoadhesive gelatin based buccal films",
pages = "122",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6078"
}

Jovanović, M. N., Radisavljević, A. N., Petrović, M. M., Stojanović, D. B., Ibrić, S. R.,& Uskoković, P. S.. (2021). 3D printed mucoadhesive gelatin based buccal films. in Twenty-second Annual Conference YUCOMAT 2021, Herceg Novi, Montenegro
Belgrade : Materials Research Society of Serbia., 122.
https://hdl.handle.net/21.15107/rcub_technorep_6078

Jovanović MN, Radisavljević AN, Petrović MM, Stojanović DB, Ibrić SR, Uskoković PS. 3D printed mucoadhesive gelatin based buccal films. in Twenty-second Annual Conference YUCOMAT 2021, Herceg Novi, Montenegro. 2021;:122.
https://hdl.handle.net/21.15107/rcub_technorep_6078 .

Jovanović, Marija N., Radisavljević, Anđela N., Petrović, Miloš M., Stojanović, Dušica B., Ibrić, Svetlana R., Uskoković, Petar S., "3D printed mucoadhesive gelatin based buccal films" in Twenty-second Annual Conference YUCOMAT 2021, Herceg Novi, Montenegro (2021):122,
https://hdl.handle.net/21.15107/rcub_technorep_6078 .

TY  - CONF
AU  - Gruden-Movsesijan, Alisa
AU  - Tomić, Sergej
AU  - Ilić, Nataša
AU  - Đokić, Jelena
AU  - Glamočlija, Sofija
AU  - Vasilev, Saša
AU  - Sabljić, Ljiljana
AU  - Stojanović, Dušica
AU  - Miljković, Đorđe
AU  - Dinić, Miroslav
AU  - Radojević, Dušan
AU  - Jevtić, Bojan
AU  - Golić, Nataša
AU  - Uskoković, Petar
AU  - Sofronić-Milosavljević, Ljiljana
AU  - Čolić, Miodrag
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6671
AB  - Trichinella spiralis possess the potential to induce tolerance and restrain excessive immune responses, thus
exerting beneficial effect on the outcome of experimental autoimmune encephalomyelitis (EAE), the animal
model of human disease multiple sclerosis. Trichinella achieves this by continuous release of its excretoysecretory (ES L1) products in the form of a complex mixture of individual components and extracellular vesicles
(TsEVs), preferentially exsosomes. Our previous results suggested that the complex modulation of the host
immune response is achieved by ES L1 products or its individula components, which induce the maturation
of dendritic cells towards tolerogenic status. A new delivery system, based on nanomaterials as carriers of ES
L1, was designed to resemble what happens in nature, ie. spontaneous release of Trichinella products over
an extended period of time using a less invasive route of administration than all previously described for the
treatment of autoimmune diseases. PLGA biodegradable nanofibers loaded with ES L1 (PLGA-ES L1), were
used as subcutaneous implants. The tretment proved to be safe with no side effects, successful in delivering
parasite products and mitigating the course of relapsing/remitting EAE in Dark Agouti rats. The mechanisms
we examined included events at the systemic level and target tissue, spinal cord, that explain the shift from the
pro- to anti-inflammatory responses and success of treatment. PLGA-ES L1 treatment also prevents the EAEinduced disruption of intestinal epithelial barrier. It diminished the inflammation by lowering the expression
of TNF-α in gastrointestinal tract (GIT) and succesfully maintain the expression of mRNA for claudin, the most
important tight junction protein in GIT. Obseved protective effect was acompained with the re-establishment of gut microbiota diversity that was disturbed in EAE-induced animals.
PB  - Belgrade : Serbian Society for Parasitology
C3  - Programme & Abstract Book / 13th European Multicolloquium of Parasitology Belgrade, October 12-16
T1  - New delivery system for Trichinella spiralis antigens - accelerated approach to autoimmunity treatment
SP  - 92
UR  - https://hdl.handle.net/21.15107/rcub_technorep_6671
ER  - 

@conference{
author = "Gruden-Movsesijan, Alisa and Tomić, Sergej and Ilić, Nataša and Đokić, Jelena and Glamočlija, Sofija and Vasilev, Saša and Sabljić, Ljiljana and Stojanović, Dušica and Miljković, Đorđe and Dinić, Miroslav and Radojević, Dušan and Jevtić, Bojan and Golić, Nataša and Uskoković, Petar and Sofronić-Milosavljević, Ljiljana and Čolić, Miodrag",
year = "2021",
abstract = "Trichinella spiralis possess the potential to induce tolerance and restrain excessive immune responses, thus
exerting beneficial effect on the outcome of experimental autoimmune encephalomyelitis (EAE), the animal
model of human disease multiple sclerosis. Trichinella achieves this by continuous release of its excretoysecretory (ES L1) products in the form of a complex mixture of individual components and extracellular vesicles
(TsEVs), preferentially exsosomes. Our previous results suggested that the complex modulation of the host
immune response is achieved by ES L1 products or its individula components, which induce the maturation
of dendritic cells towards tolerogenic status. A new delivery system, based on nanomaterials as carriers of ES
L1, was designed to resemble what happens in nature, ie. spontaneous release of Trichinella products over
an extended period of time using a less invasive route of administration than all previously described for the
treatment of autoimmune diseases. PLGA biodegradable nanofibers loaded with ES L1 (PLGA-ES L1), were
used as subcutaneous implants. The tretment proved to be safe with no side effects, successful in delivering
parasite products and mitigating the course of relapsing/remitting EAE in Dark Agouti rats. The mechanisms
we examined included events at the systemic level and target tissue, spinal cord, that explain the shift from the
pro- to anti-inflammatory responses and success of treatment. PLGA-ES L1 treatment also prevents the EAEinduced disruption of intestinal epithelial barrier. It diminished the inflammation by lowering the expression
of TNF-α in gastrointestinal tract (GIT) and succesfully maintain the expression of mRNA for claudin, the most
important tight junction protein in GIT. Obseved protective effect was acompained with the re-establishment of gut microbiota diversity that was disturbed in EAE-induced animals.",
publisher = "Belgrade : Serbian Society for Parasitology",
journal = "Programme & Abstract Book / 13th European Multicolloquium of Parasitology Belgrade, October 12-16",
title = "New delivery system for Trichinella spiralis antigens - accelerated approach to autoimmunity treatment",
pages = "92",
url = "https://hdl.handle.net/21.15107/rcub_technorep_6671"
}

Gruden-Movsesijan, A., Tomić, S., Ilić, N., Đokić, J., Glamočlija, S., Vasilev, S., Sabljić, L., Stojanović, D., Miljković, Đ., Dinić, M., Radojević, D., Jevtić, B., Golić, N., Uskoković, P., Sofronić-Milosavljević, L.,& Čolić, M.. (2021). New delivery system for Trichinella spiralis antigens - accelerated approach to autoimmunity treatment. in Programme & Abstract Book / 13th European Multicolloquium of Parasitology Belgrade, October 12-16
Belgrade : Serbian Society for Parasitology., 92.
https://hdl.handle.net/21.15107/rcub_technorep_6671

Gruden-Movsesijan A, Tomić S, Ilić N, Đokić J, Glamočlija S, Vasilev S, Sabljić L, Stojanović D, Miljković Đ, Dinić M, Radojević D, Jevtić B, Golić N, Uskoković P, Sofronić-Milosavljević L, Čolić M. New delivery system for Trichinella spiralis antigens - accelerated approach to autoimmunity treatment. in Programme & Abstract Book / 13th European Multicolloquium of Parasitology Belgrade, October 12-16. 2021;:92.
https://hdl.handle.net/21.15107/rcub_technorep_6671 .

Gruden-Movsesijan, Alisa, Tomić, Sergej, Ilić, Nataša, Đokić, Jelena, Glamočlija, Sofija, Vasilev, Saša, Sabljić, Ljiljana, Stojanović, Dušica, Miljković, Đorđe, Dinić, Miroslav, Radojević, Dušan, Jevtić, Bojan, Golić, Nataša, Uskoković, Petar, Sofronić-Milosavljević, Ljiljana, Čolić, Miodrag, "New delivery system for Trichinella spiralis antigens - accelerated approach to autoimmunity treatment" in Programme & Abstract Book / 13th European Multicolloquium of Parasitology Belgrade, October 12-16 (2021):92,
https://hdl.handle.net/21.15107/rcub_technorep_6671 .

TY  - JOUR
AU  - Jovanović, Marija
AU  - Petrović, Miloš
AU  - Cvijic, Sandra
AU  - Tomić, Nataša
AU  - Stojanović, Dušica
AU  - Ibric, Svetlana
AU  - Uskoković, Petar
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4778
AB  - Gelatin-polyvinylpyrrolidone (PVP) and gelatin-poly(vinyl alcohol) (PVA) mucoadhesive buccal films loaded with propranolol hydrochloride (PRH) were prepared by semi-solid extrusion 3D printing. The aim of this study was to evaluate the effects of the synthetic polymers PVP and PVA on thermal and mechanical properties and drug release profiles of gelatin-based films. The Fourier-transform infrared spectroscopy showed that hydrogen bonding between gelatin and PVP formed during printing. In the other blend, neither the esterification of PVA nor gelatin occurred. Differential scanning calorimetry revealed the presence of partial helical structures. In line with these results, the mechanical properties and drug release profiles were different for each blend. Formulation with gelatin-PVP and PRH showed higher tensile strength, hardness, and adhesive strength but slower drug release than formulation with gelatin-PVA and PRH. The in silico population simulations indicated increased drug bioavailability and decreased inter-individual variations in the resulting pharmacokinetic profiles compared to immediate-release tablets. Moreover, the simulation results suggested that reduced PRH daily dosing can be achieved with prolonged-release buccal films, which improves patient compliance.
T2  - Pharmaceutics
T1  - 3D Printed Buccal Films for Prolonged-Release of Propranolol Hydrochloride: Development, Characterization and Bioavailability Prediction
IS  - 12
VL  - 13
DO  - 10.3390/pharmaceutics13122143
ER  - 

@article{
author = "Jovanović, Marija and Petrović, Miloš and Cvijic, Sandra and Tomić, Nataša and Stojanović, Dušica and Ibric, Svetlana and Uskoković, Petar",
year = "2021",
abstract = "Gelatin-polyvinylpyrrolidone (PVP) and gelatin-poly(vinyl alcohol) (PVA) mucoadhesive buccal films loaded with propranolol hydrochloride (PRH) were prepared by semi-solid extrusion 3D printing. The aim of this study was to evaluate the effects of the synthetic polymers PVP and PVA on thermal and mechanical properties and drug release profiles of gelatin-based films. The Fourier-transform infrared spectroscopy showed that hydrogen bonding between gelatin and PVP formed during printing. In the other blend, neither the esterification of PVA nor gelatin occurred. Differential scanning calorimetry revealed the presence of partial helical structures. In line with these results, the mechanical properties and drug release profiles were different for each blend. Formulation with gelatin-PVP and PRH showed higher tensile strength, hardness, and adhesive strength but slower drug release than formulation with gelatin-PVA and PRH. The in silico population simulations indicated increased drug bioavailability and decreased inter-individual variations in the resulting pharmacokinetic profiles compared to immediate-release tablets. Moreover, the simulation results suggested that reduced PRH daily dosing can be achieved with prolonged-release buccal films, which improves patient compliance.",
journal = "Pharmaceutics",
title = "3D Printed Buccal Films for Prolonged-Release of Propranolol Hydrochloride: Development, Characterization and Bioavailability Prediction",
number = "12",
volume = "13",
doi = "10.3390/pharmaceutics13122143"
}

Jovanović, M., Petrović, M., Cvijic, S., Tomić, N., Stojanović, D., Ibric, S.,& Uskoković, P.. (2021). 3D Printed Buccal Films for Prolonged-Release of Propranolol Hydrochloride: Development, Characterization and Bioavailability Prediction. in Pharmaceutics, 13(12).
https://doi.org/10.3390/pharmaceutics13122143

Jovanović M, Petrović M, Cvijic S, Tomić N, Stojanović D, Ibric S, Uskoković P. 3D Printed Buccal Films for Prolonged-Release of Propranolol Hydrochloride: Development, Characterization and Bioavailability Prediction. in Pharmaceutics. 2021;13(12).
doi:10.3390/pharmaceutics13122143 .

Jovanović, Marija, Petrović, Miloš, Cvijic, Sandra, Tomić, Nataša, Stojanović, Dušica, Ibric, Svetlana, Uskoković, Petar, "3D Printed Buccal Films for Prolonged-Release of Propranolol Hydrochloride: Development, Characterization and Bioavailability Prediction" in Pharmaceutics, 13, no. 12 (2021),
https://doi.org/10.3390/pharmaceutics13122143 . .

TY  - JOUR
AU  - Jovanović, Marija
AU  - Tomić, Nataša
AU  - Cvijic, Sandra
AU  - Stojanović, Dušica
AU  - Ibric, Svetlana
AU  - Uskoković, Petar
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4909
AB  - This study processes and characterizes propranolol hydrochloride/gelatin mucoadhesive buccal films. Two types of gelatin are used: Gelatin from porcine skin, type A (GA), and gelatin from bovine skin (GB). The influence of gelatin type on mechanical, mucoadhesive, and biopharmaceutical characteristics of buccal films is evaluated. Fourier-Transfer infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC) analysis show that GA with propranolol hydrochloride (PRH) in the film (GAP) formed a physical mixture, whereas GB with PRH (GBP) form a compound-complex. Results of mechanical testing (tensile test, hardness) revealed that GAP films exhibit higher elastic modulus, tensile strength, and hardness. A mucoahesion test shows that GBP has higher adhesion strength, while GAP shows higher work of adhesion. Both in vitro release study and in silico simulation indicated that processed films can provide effective drug transport through the buccal mucosa. In silico simulation shows improved bioavailability from buccal films, in comparison to the immediate-release tablets-indicating that the therapeutic drug dose can be markedly reduced.
T2  - Pharmaceutics
T1  - Mucoadhesive Gelatin Buccal Films with Propranolol Hydrochloride: Evaluation of Mechanical, Mucoadhesive, and Biopharmaceutical Properties
IS  - 2
VL  - 13
DO  - 10.3390/pharmaceutics13020273
ER  - 

@article{
author = "Jovanović, Marija and Tomić, Nataša and Cvijic, Sandra and Stojanović, Dušica and Ibric, Svetlana and Uskoković, Petar",
year = "2021",
abstract = "This study processes and characterizes propranolol hydrochloride/gelatin mucoadhesive buccal films. Two types of gelatin are used: Gelatin from porcine skin, type A (GA), and gelatin from bovine skin (GB). The influence of gelatin type on mechanical, mucoadhesive, and biopharmaceutical characteristics of buccal films is evaluated. Fourier-Transfer infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC) analysis show that GA with propranolol hydrochloride (PRH) in the film (GAP) formed a physical mixture, whereas GB with PRH (GBP) form a compound-complex. Results of mechanical testing (tensile test, hardness) revealed that GAP films exhibit higher elastic modulus, tensile strength, and hardness. A mucoahesion test shows that GBP has higher adhesion strength, while GAP shows higher work of adhesion. Both in vitro release study and in silico simulation indicated that processed films can provide effective drug transport through the buccal mucosa. In silico simulation shows improved bioavailability from buccal films, in comparison to the immediate-release tablets-indicating that the therapeutic drug dose can be markedly reduced.",
journal = "Pharmaceutics",
title = "Mucoadhesive Gelatin Buccal Films with Propranolol Hydrochloride: Evaluation of Mechanical, Mucoadhesive, and Biopharmaceutical Properties",
number = "2",
volume = "13",
doi = "10.3390/pharmaceutics13020273"
}

Jovanović, M., Tomić, N., Cvijic, S., Stojanović, D., Ibric, S.,& Uskoković, P.. (2021). Mucoadhesive Gelatin Buccal Films with Propranolol Hydrochloride: Evaluation of Mechanical, Mucoadhesive, and Biopharmaceutical Properties. in Pharmaceutics, 13(2).
https://doi.org/10.3390/pharmaceutics13020273

Jovanović M, Tomić N, Cvijic S, Stojanović D, Ibric S, Uskoković P. Mucoadhesive Gelatin Buccal Films with Propranolol Hydrochloride: Evaluation of Mechanical, Mucoadhesive, and Biopharmaceutical Properties. in Pharmaceutics. 2021;13(2).
doi:10.3390/pharmaceutics13020273 .

Jovanović, Marija, Tomić, Nataša, Cvijic, Sandra, Stojanović, Dušica, Ibric, Svetlana, Uskoković, Petar, "Mucoadhesive Gelatin Buccal Films with Propranolol Hydrochloride: Evaluation of Mechanical, Mucoadhesive, and Biopharmaceutical Properties" in Pharmaceutics, 13, no. 2 (2021),
https://doi.org/10.3390/pharmaceutics13020273 . .