TY  - JOUR
AU  - Gvozdić, Eleonora
AU  - Bujagić Matić, Ivana
AU  - Đurkić, Tatjana
AU  - Grujić, Svetlana
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6598
AB  - Artificial sweeteners are receiving increasing attention as newly recognized emerging contaminants that mainly reach the aquatic environment through the discharge of municipal wastewater containing large amount of these compounds. In this study, the impact of raw untreated wastewater discharges on the levels and the water/sediment distribution of artificial sweeteners in the Danube River and its largest tributaries in Serbia was evaluated, and a comprehensive assessment of environmental risks for freshwater and benthic organisms was performed. Acesulfame and sucralose were detected in all river water samples (100%), while saccharin (59%) and cyclamate (12%) were less frequently found, indicating long-term continuous sewage-derived pollution. Aspartame (100%) and neotame (60%) were the only artificial sweeteners recorded in the sediment samples due to their preference to sorb to particulate matter in the water/sediment system. In terms of ecotoxicological risk, a low risk for aquatic organisms was determined at the detected levels of saccharin in river water, while a high to medium risk was found for benthic biota at the concentrations of neotame and aspartame detected in sediments. The largest contribution to the pollution of the Danube River Basin with artificial sweeteners, and consequently the highest environmental risk, was determined in the two largest cities, the capital Belgrade and Novi Sad, which raises the issue of transboundary pollution.
PB  - Springer Science and Business Media Deutschland GmbH
T2  - Environmental Science and Pollution Research
T1  - Untreated wastewater impact and environmental risk assessment of artificial sweeteners in river water and sediments of the Danube River Basin in Serbia
EP  - 84594
SP  - 84583
VL  - 30
DO  - 10.1007/s11356-023-28348-5
ER  - 

@article{
author = "Gvozdić, Eleonora and Bujagić Matić, Ivana and Đurkić, Tatjana and Grujić, Svetlana",
year = "2023",
abstract = "Artificial sweeteners are receiving increasing attention as newly recognized emerging contaminants that mainly reach the aquatic environment through the discharge of municipal wastewater containing large amount of these compounds. In this study, the impact of raw untreated wastewater discharges on the levels and the water/sediment distribution of artificial sweeteners in the Danube River and its largest tributaries in Serbia was evaluated, and a comprehensive assessment of environmental risks for freshwater and benthic organisms was performed. Acesulfame and sucralose were detected in all river water samples (100%), while saccharin (59%) and cyclamate (12%) were less frequently found, indicating long-term continuous sewage-derived pollution. Aspartame (100%) and neotame (60%) were the only artificial sweeteners recorded in the sediment samples due to their preference to sorb to particulate matter in the water/sediment system. In terms of ecotoxicological risk, a low risk for aquatic organisms was determined at the detected levels of saccharin in river water, while a high to medium risk was found for benthic biota at the concentrations of neotame and aspartame detected in sediments. The largest contribution to the pollution of the Danube River Basin with artificial sweeteners, and consequently the highest environmental risk, was determined in the two largest cities, the capital Belgrade and Novi Sad, which raises the issue of transboundary pollution.",
publisher = "Springer Science and Business Media Deutschland GmbH",
journal = "Environmental Science and Pollution Research",
title = "Untreated wastewater impact and environmental risk assessment of artificial sweeteners in river water and sediments of the Danube River Basin in Serbia",
pages = "84594-84583",
volume = "30",
doi = "10.1007/s11356-023-28348-5"
}

Gvozdić, E., Bujagić Matić, I., Đurkić, T.,& Grujić, S.. (2023). Untreated wastewater impact and environmental risk assessment of artificial sweeteners in river water and sediments of the Danube River Basin in Serbia. in Environmental Science and Pollution Research
Springer Science and Business Media Deutschland GmbH., 30, 84583-84594.
https://doi.org/10.1007/s11356-023-28348-5

Gvozdić E, Bujagić Matić I, Đurkić T, Grujić S. Untreated wastewater impact and environmental risk assessment of artificial sweeteners in river water and sediments of the Danube River Basin in Serbia. in Environmental Science and Pollution Research. 2023;30:84583-84594.
doi:10.1007/s11356-023-28348-5 .

Gvozdić, Eleonora, Bujagić Matić, Ivana, Đurkić, Tatjana, Grujić, Svetlana, "Untreated wastewater impact and environmental risk assessment of artificial sweeteners in river water and sediments of the Danube River Basin in Serbia" in Environmental Science and Pollution Research, 30 (2023):84583-84594,
https://doi.org/10.1007/s11356-023-28348-5 . .

TY  - CONF
AU  - Gvozdić, Eleonora
AU  - Matić Bujagić, Ivana
AU  - Đurkić, Tatjana
AU  - Grujić, Svetlana
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7029
AB  - Artificial sweeteners are high-priority emerging contaminants that are widespread in surface waters worldwide as a result of municipal wastewater discharges into the aquatic environment. Given that these substances can cause toxic effects on aquatic organisms, they represent a potential risk for the river ecosystem as a whole. Although sediments have not often been the subject of scientific research on pollution with artificial sweeteners, there is a possibility that these substances pose a risk to sediment-dwelling organisms. Aspartame and neotame are sweeteners that have a high sorption affinity for organic-rich particles and partition to sediment in the water-sediment system. In order to determine the possible risk for benthic biota, an ecological risk assessment of detected aspartame and neotame in sediments from five rivers in Serbia was performed. In addition to the risk assessment of individual sweeteners, “the cocktail effect” of their mixture was also estimated. Detected levels were compared with the lowest predicted no-effect concentration (PNEC) values for sediment organisms from the Norman Ecotoxicology Database, based on experimental ecotoxicity data and QSAR model predictions for aquatic organisms.
PB  - Belgrade : The Academy of Applied Technical Studies "Belgrade"
C3  - Conference Proceedings / International Scientific and Professional Conference Politehnika 2023, Belgrade, 15th December 2023
T1  - ECOLOGICAL RISK ASSESSMENT OF ASPARTAME AND NEOTAME IN RIVER SEDIMENTS
EP  - 99
SP  - 95
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7029
ER  - 

@conference{
author = "Gvozdić, Eleonora and Matić Bujagić, Ivana and Đurkić, Tatjana and Grujić, Svetlana",
year = "2023",
abstract = "Artificial sweeteners are high-priority emerging contaminants that are widespread in surface waters worldwide as a result of municipal wastewater discharges into the aquatic environment. Given that these substances can cause toxic effects on aquatic organisms, they represent a potential risk for the river ecosystem as a whole. Although sediments have not often been the subject of scientific research on pollution with artificial sweeteners, there is a possibility that these substances pose a risk to sediment-dwelling organisms. Aspartame and neotame are sweeteners that have a high sorption affinity for organic-rich particles and partition to sediment in the water-sediment system. In order to determine the possible risk for benthic biota, an ecological risk assessment of detected aspartame and neotame in sediments from five rivers in Serbia was performed. In addition to the risk assessment of individual sweeteners, “the cocktail effect” of their mixture was also estimated. Detected levels were compared with the lowest predicted no-effect concentration (PNEC) values for sediment organisms from the Norman Ecotoxicology Database, based on experimental ecotoxicity data and QSAR model predictions for aquatic organisms.",
publisher = "Belgrade : The Academy of Applied Technical Studies "Belgrade"",
journal = "Conference Proceedings / International Scientific and Professional Conference Politehnika 2023, Belgrade, 15th December 2023",
title = "ECOLOGICAL RISK ASSESSMENT OF ASPARTAME AND NEOTAME IN RIVER SEDIMENTS",
pages = "99-95",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7029"
}

Gvozdić, E., Matić Bujagić, I., Đurkić, T.,& Grujić, S.. (2023). ECOLOGICAL RISK ASSESSMENT OF ASPARTAME AND NEOTAME IN RIVER SEDIMENTS. in Conference Proceedings / International Scientific and Professional Conference Politehnika 2023, Belgrade, 15th December 2023
Belgrade : The Academy of Applied Technical Studies "Belgrade"., 95-99.
https://hdl.handle.net/21.15107/rcub_technorep_7029

Gvozdić E, Matić Bujagić I, Đurkić T, Grujić S. ECOLOGICAL RISK ASSESSMENT OF ASPARTAME AND NEOTAME IN RIVER SEDIMENTS. in Conference Proceedings / International Scientific and Professional Conference Politehnika 2023, Belgrade, 15th December 2023. 2023;:95-99.
https://hdl.handle.net/21.15107/rcub_technorep_7029 .

Gvozdić, Eleonora, Matić Bujagić, Ivana, Đurkić, Tatjana, Grujić, Svetlana, "ECOLOGICAL RISK ASSESSMENT OF ASPARTAME AND NEOTAME IN RIVER SEDIMENTS" in Conference Proceedings / International Scientific and Professional Conference Politehnika 2023, Belgrade, 15th December 2023 (2023):95-99,
https://hdl.handle.net/21.15107/rcub_technorep_7029 .

TY  - CONF
AU  - Tolić Stojadinović, Ljiljana
AU  - Grujić, Svetlana
AU  - Antić, Nikolina
AU  - Đurkić, Tatjana
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7248
AB  - Municipal wastewater in the Belgrade area is discharged into the Danube and the Sava
Rivers without any treatment. This affects the quality of river water since wastewater is one of the
most important sources of environmental pollutants, including pharmaceuticals. To assess the impact
of this effect, the presence of three commonly used antibiotics in wastewater and receiving river water
was determined. A previously developed liquid chromatography-tandem mass spectrometry method
for the analysis of antibiotics in natural water matrices was validated for wastewater and applied in
analysis of samples from the Belgrade area. All investigated antibiotics were detected in both
wastewater and river water samples. The highest concentration of antibiotics in wastewater was
found for sulfamethoxazole, while trimethoprim was detected at the highest level in surface water.
The most frequently detected antibiotic in surface water was azithromycin. The environmental risk
assessment was performed for surface water biota. Azithromycin was found to pose a high risk to
aquatic organisms, while the risk level of sulfamethoxazole was medium or low. In conclusion, the
obtained results show the detrimental impact of untreated wastewater discharge on the river water
quality in the Belgrade area, emphasizing the need for urban wastewater treatment.
PB  - Belgrade : The Academy of Applied Technical Studies "Belgrade"
C3  - Conference Proceedings / International Scientific and Professional Conference Politehnika 2023, Belgrade, 15th December 2023
T1  - Impact of wastewater antibiotics on river water quality in Belgrade area
EP  - 59
SP  - 54
UR  - https://hdl.handle.net/21.15107/rcub_technorep_7248
ER  - 

@conference{
author = "Tolić Stojadinović, Ljiljana and Grujić, Svetlana and Antić, Nikolina and Đurkić, Tatjana",
year = "2023",
abstract = "Municipal wastewater in the Belgrade area is discharged into the Danube and the Sava
Rivers without any treatment. This affects the quality of river water since wastewater is one of the
most important sources of environmental pollutants, including pharmaceuticals. To assess the impact
of this effect, the presence of three commonly used antibiotics in wastewater and receiving river water
was determined. A previously developed liquid chromatography-tandem mass spectrometry method
for the analysis of antibiotics in natural water matrices was validated for wastewater and applied in
analysis of samples from the Belgrade area. All investigated antibiotics were detected in both
wastewater and river water samples. The highest concentration of antibiotics in wastewater was
found for sulfamethoxazole, while trimethoprim was detected at the highest level in surface water.
The most frequently detected antibiotic in surface water was azithromycin. The environmental risk
assessment was performed for surface water biota. Azithromycin was found to pose a high risk to
aquatic organisms, while the risk level of sulfamethoxazole was medium or low. In conclusion, the
obtained results show the detrimental impact of untreated wastewater discharge on the river water
quality in the Belgrade area, emphasizing the need for urban wastewater treatment.",
publisher = "Belgrade : The Academy of Applied Technical Studies "Belgrade"",
journal = "Conference Proceedings / International Scientific and Professional Conference Politehnika 2023, Belgrade, 15th December 2023",
title = "Impact of wastewater antibiotics on river water quality in Belgrade area",
pages = "59-54",
url = "https://hdl.handle.net/21.15107/rcub_technorep_7248"
}

Tolić Stojadinović, L., Grujić, S., Antić, N.,& Đurkić, T.. (2023). Impact of wastewater antibiotics on river water quality in Belgrade area. in Conference Proceedings / International Scientific and Professional Conference Politehnika 2023, Belgrade, 15th December 2023
Belgrade : The Academy of Applied Technical Studies "Belgrade"., 54-59.
https://hdl.handle.net/21.15107/rcub_technorep_7248

Tolić Stojadinović L, Grujić S, Antić N, Đurkić T. Impact of wastewater antibiotics on river water quality in Belgrade area. in Conference Proceedings / International Scientific and Professional Conference Politehnika 2023, Belgrade, 15th December 2023. 2023;:54-59.
https://hdl.handle.net/21.15107/rcub_technorep_7248 .

Tolić Stojadinović, Ljiljana, Grujić, Svetlana, Antić, Nikolina, Đurkić, Tatjana, "Impact of wastewater antibiotics on river water quality in Belgrade area" in Conference Proceedings / International Scientific and Professional Conference Politehnika 2023, Belgrade, 15th December 2023 (2023):54-59,
https://hdl.handle.net/21.15107/rcub_technorep_7248 .

TY  - JOUR
AU  - Jaćimović, Nevena
AU  - Đošić, Marija
AU  - Janković, Ana
AU  - Grujić, Svetlana
AU  - Matić Bujagić, Ivana
AU  - Stojanović, Jovica
AU  - Vukašinović-Sekulić, Maja
AU  - Kojić, Vesna
AU  - Mišković-Stanković, Vesna
PY  - 2023
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/7260
AB  - Biocomposite hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coatings were fabricated on titanium by an electrophoretic deposition process (EPD) from an aqueous suspension using the constant voltage method. Characterization of the deposited coatings was performed by scanning electron micros-copy with field emission (FE-SEM), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD) after immersion in simulated body fluid (SBF) at 37 °C. The concentration of the released gentamicin was determined using high-performance liquid chromatography (HPLC) coupled with a mass spectrometer (MS). The release profile confirmed an initial “burst-release effect” with ~ 30 % of the gen-tamicin released in the first 48 h, which could be of assistance in the prevention of biofilm formation. An-tibacterial activity was proven by the agar diffusion method on Staphylococcus aureus TL and Escherich-ia coli ATCC 25922 bacterial strains. Cytotoxicity was tested by the dye exclusion test (DET) on MRC-5 and L929 fibroblast cell lines, with both coatings expressing nontoxicity. The results showed the high ap-plicability potential of a poly(vinyl alcohol)-based biocomposite coating for medical purposes.
PB  - Society of Chemists and Technologists of Macedonia
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Single-step, electrophoretically deposited hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coating for biomedical applications
EP  - 262
IS  - 2
SP  - 249
VL  - 42
DO  - 10.20450/mjcce.2023.2775
ER  - 

@article{
author = "Jaćimović, Nevena and Đošić, Marija and Janković, Ana and Grujić, Svetlana and Matić Bujagić, Ivana and Stojanović, Jovica and Vukašinović-Sekulić, Maja and Kojić, Vesna and Mišković-Stanković, Vesna",
year = "2023",
abstract = "Biocomposite hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coatings were fabricated on titanium by an electrophoretic deposition process (EPD) from an aqueous suspension using the constant voltage method. Characterization of the deposited coatings was performed by scanning electron micros-copy with field emission (FE-SEM), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD) after immersion in simulated body fluid (SBF) at 37 °C. The concentration of the released gentamicin was determined using high-performance liquid chromatography (HPLC) coupled with a mass spectrometer (MS). The release profile confirmed an initial “burst-release effect” with ~ 30 % of the gen-tamicin released in the first 48 h, which could be of assistance in the prevention of biofilm formation. An-tibacterial activity was proven by the agar diffusion method on Staphylococcus aureus TL and Escherich-ia coli ATCC 25922 bacterial strains. Cytotoxicity was tested by the dye exclusion test (DET) on MRC-5 and L929 fibroblast cell lines, with both coatings expressing nontoxicity. The results showed the high ap-plicability potential of a poly(vinyl alcohol)-based biocomposite coating for medical purposes.",
publisher = "Society of Chemists and Technologists of Macedonia",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Single-step, electrophoretically deposited hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coating for biomedical applications",
pages = "262-249",
number = "2",
volume = "42",
doi = "10.20450/mjcce.2023.2775"
}

Jaćimović, N., Đošić, M., Janković, A., Grujić, S., Matić Bujagić, I., Stojanović, J., Vukašinović-Sekulić, M., Kojić, V.,& Mišković-Stanković, V.. (2023). Single-step, electrophoretically deposited hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coating for biomedical applications. in Macedonian Journal of Chemistry and Chemical Engineering
Society of Chemists and Technologists of Macedonia., 42(2), 249-262.
https://doi.org/10.20450/mjcce.2023.2775

Jaćimović N, Đošić M, Janković A, Grujić S, Matić Bujagić I, Stojanović J, Vukašinović-Sekulić M, Kojić V, Mišković-Stanković V. Single-step, electrophoretically deposited hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coating for biomedical applications. in Macedonian Journal of Chemistry and Chemical Engineering. 2023;42(2):249-262.
doi:10.20450/mjcce.2023.2775 .

Jaćimović, Nevena, Đošić, Marija, Janković, Ana, Grujić, Svetlana, Matić Bujagić, Ivana, Stojanović, Jovica, Vukašinović-Sekulić, Maja, Kojić, Vesna, Mišković-Stanković, Vesna, "Single-step, electrophoretically deposited hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coating for biomedical applications" in Macedonian Journal of Chemistry and Chemical Engineering, 42, no. 2 (2023):249-262,
https://doi.org/10.20450/mjcce.2023.2775 . .

TY  - CHAP
AU  - Matić Bujagić, Ivana
AU  - Gvozdić, Eleonora
AU  - Đurkić, Tatjana
AU  - Grujić, Svetlana
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5949
AB  - This is the first study of a broad range of chemical classes of emerging contaminants conducted by analyzing influent and effluent samples from the wastewater treatment plant of the city Topola, in Serbia. The list of compounds is extensive and this paper provides a better understanding of the environmental burden from different classes of emerging contaminants. The samples were prepared using an optimized solid-phase extraction method and analyzed by liquid chromatography-tandem mass spectrometry. Removal patterns of selected compounds are discussed based on their physico-chemical properties and detected concentrations. Significant removal efficiencies, exceeding 70%, were found for the majority of investigated pharmaceuticals, pesticides, steroids, and sweeteners. Ecotoxicological risk assessment was performed by using two complementary methods: (1) an individual substance approach, based on the calculation of risk quotients (RQs) for each substance as the ratio of Predicted Environmental Concentration (PEC) and Predicted No Effect Concentration (PNEC), and (2) mixture risk assessment (“the cocktail effect”) based on the summation of individual RQs. The classical approach (ERA method with individual substances) identified amlodipine as the riskiest substance in WWTP effluent. The mixture ERA approach revealed new risks, which were not recog-nized by the classical ERA method, indicating that individually “safe” emerging compounds can contribute to a significant risk of the whole effluents.
PB  - Springer, Cham
T2  - CNNTech 2021. Lecture Notes in Networks and Systems
T1  - Occurrence and Ecotoxicological Risk Assessment of Emerging Contaminants in Urban Wastewater Treatment Plant
VL  - 23
DO  - 10.1007/978-3-030-86009-7_8
ER  - 

@inbook{
author = "Matić Bujagić, Ivana and Gvozdić, Eleonora and Đurkić, Tatjana and Grujić, Svetlana",
year = "2022",
abstract = "This is the first study of a broad range of chemical classes of emerging contaminants conducted by analyzing influent and effluent samples from the wastewater treatment plant of the city Topola, in Serbia. The list of compounds is extensive and this paper provides a better understanding of the environmental burden from different classes of emerging contaminants. The samples were prepared using an optimized solid-phase extraction method and analyzed by liquid chromatography-tandem mass spectrometry. Removal patterns of selected compounds are discussed based on their physico-chemical properties and detected concentrations. Significant removal efficiencies, exceeding 70%, were found for the majority of investigated pharmaceuticals, pesticides, steroids, and sweeteners. Ecotoxicological risk assessment was performed by using two complementary methods: (1) an individual substance approach, based on the calculation of risk quotients (RQs) for each substance as the ratio of Predicted Environmental Concentration (PEC) and Predicted No Effect Concentration (PNEC), and (2) mixture risk assessment (“the cocktail effect”) based on the summation of individual RQs. The classical approach (ERA method with individual substances) identified amlodipine as the riskiest substance in WWTP effluent. The mixture ERA approach revealed new risks, which were not recog-nized by the classical ERA method, indicating that individually “safe” emerging compounds can contribute to a significant risk of the whole effluents.",
publisher = "Springer, Cham",
journal = "CNNTech 2021. Lecture Notes in Networks and Systems",
booktitle = "Occurrence and Ecotoxicological Risk Assessment of Emerging Contaminants in Urban Wastewater Treatment Plant",
volume = "23",
doi = "10.1007/978-3-030-86009-7_8"
}

Matić Bujagić, I., Gvozdić, E., Đurkić, T.,& Grujić, S.. (2022). Occurrence and Ecotoxicological Risk Assessment of Emerging Contaminants in Urban Wastewater Treatment Plant. in CNNTech 2021. Lecture Notes in Networks and Systems
Springer, Cham., 23.
https://doi.org/10.1007/978-3-030-86009-7_8

Matić Bujagić I, Gvozdić E, Đurkić T, Grujić S. Occurrence and Ecotoxicological Risk Assessment of Emerging Contaminants in Urban Wastewater Treatment Plant. in CNNTech 2021. Lecture Notes in Networks and Systems. 2022;23.
doi:10.1007/978-3-030-86009-7_8 .

Matić Bujagić, Ivana, Gvozdić, Eleonora, Đurkić, Tatjana, Grujić, Svetlana, "Occurrence and Ecotoxicological Risk Assessment of Emerging Contaminants in Urban Wastewater Treatment Plant" in CNNTech 2021. Lecture Notes in Networks and Systems, 23 (2022),
https://doi.org/10.1007/978-3-030-86009-7_8 . .

TY  - CONF
AU  - Gvozdić, Eleonora Ž.
AU  - Matić Bujagić, Ivana V.
AU  - Đurkić, Tatjana M.
AU  - Grujić, Svetlana D.
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5934
AB  - Veštački zaslađivači saharin i sukraloza predstavljaju emergentne zagađujuće materije čije prisustvo u akvatičnim ekosistemima može negativno uticati na osetljive organizme. Veoma su postojani u životnoj sredini, a posebno je zabrinjavajuće njihovo toksično dejstvo na planktonske vrste. U ovom radu je izvršena HPLC–MS/MS analiza tragova saharina i sukraloze u pet uzoraka rečne vode iz Save i Dunava na teritoriji Beograda radi procene prisustva i određivanja ekotoksikološkog rizika. Rezultati su pokazali da detektovane koncentracije ovih zaslađivača u reci Dunav (do 396 ng L–1 za saharin i do 349 ng L–1 za sukralozu) pokazuju nizak ekotoksikološki rizik za vodene organizme, ali zbog “koktel efekta” njihov kumulativni doprinos može predstavljati veći rizik po vodeni svet.
PB  - Beograd : Srpsko hemijsko društvo
C3  - Kratki izvodi radova ; Knjiga radova / 58. savetovanje Srpskog hemijskog društva, Beograd, 9. i 10. jun 2022. godine
T1  - Procena ekotoksikološkog rizika veštačkih zaslađivača saharina i sukraloze u rečnoj vodi na teritoriji Beograda
EP  - 188
SP  - 186
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5934
ER  - 

@conference{
author = "Gvozdić, Eleonora Ž. and Matić Bujagić, Ivana V. and Đurkić, Tatjana M. and Grujić, Svetlana D.",
year = "2022",
abstract = "Veštački zaslađivači saharin i sukraloza predstavljaju emergentne zagađujuće materije čije prisustvo u akvatičnim ekosistemima može negativno uticati na osetljive organizme. Veoma su postojani u životnoj sredini, a posebno je zabrinjavajuće njihovo toksično dejstvo na planktonske vrste. U ovom radu je izvršena HPLC–MS/MS analiza tragova saharina i sukraloze u pet uzoraka rečne vode iz Save i Dunava na teritoriji Beograda radi procene prisustva i određivanja ekotoksikološkog rizika. Rezultati su pokazali da detektovane koncentracije ovih zaslađivača u reci Dunav (do 396 ng L–1 za saharin i do 349 ng L–1 za sukralozu) pokazuju nizak ekotoksikološki rizik za vodene organizme, ali zbog “koktel efekta” njihov kumulativni doprinos može predstavljati veći rizik po vodeni svet.",
publisher = "Beograd : Srpsko hemijsko društvo",
journal = "Kratki izvodi radova ; Knjiga radova / 58. savetovanje Srpskog hemijskog društva, Beograd, 9. i 10. jun 2022. godine",
title = "Procena ekotoksikološkog rizika veštačkih zaslađivača saharina i sukraloze u rečnoj vodi na teritoriji Beograda",
pages = "188-186",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5934"
}

Gvozdić, E. Ž., Matić Bujagić, I. V., Đurkić, T. M.,& Grujić, S. D.. (2022). Procena ekotoksikološkog rizika veštačkih zaslađivača saharina i sukraloze u rečnoj vodi na teritoriji Beograda. in Kratki izvodi radova ; Knjiga radova / 58. savetovanje Srpskog hemijskog društva, Beograd, 9. i 10. jun 2022. godine
Beograd : Srpsko hemijsko društvo., 186-188.
https://hdl.handle.net/21.15107/rcub_technorep_5934

Gvozdić EŽ, Matić Bujagić IV, Đurkić TM, Grujić SD. Procena ekotoksikološkog rizika veštačkih zaslađivača saharina i sukraloze u rečnoj vodi na teritoriji Beograda. in Kratki izvodi radova ; Knjiga radova / 58. savetovanje Srpskog hemijskog društva, Beograd, 9. i 10. jun 2022. godine. 2022;:186-188.
https://hdl.handle.net/21.15107/rcub_technorep_5934 .

Gvozdić, Eleonora Ž., Matić Bujagić, Ivana V., Đurkić, Tatjana M., Grujić, Svetlana D., "Procena ekotoksikološkog rizika veštačkih zaslađivača saharina i sukraloze u rečnoj vodi na teritoriji Beograda" in Kratki izvodi radova ; Knjiga radova / 58. savetovanje Srpskog hemijskog društva, Beograd, 9. i 10. jun 2022. godine (2022):186-188,
https://hdl.handle.net/21.15107/rcub_technorep_5934 .

TY  - JOUR
AU  - Jauković, Zorica
AU  - Grujić, Svetlana
AU  - Bujagić Matić, Ivana
AU  - Petković, Anđelka
AU  - Laušević, Mila
PY  - 2022
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5189
AB  - In this work, the environmental distribution of steroid compounds and the level of sewage-derived contamination were assessed using sterol ratios in the confluence area of two major rivers in the Serbian capital, where raw sewage is discharged without any treatment. Special attention was paid to steroids partitioning between the dissolved and suspended phases of river and wastewater samples, since steroids tend to easily bind to particulate matter. The efficiency of sterol removal in two wastewater treatment plants in Serbia was also evaluated. Human/animal sterols coprostanol and cholesterol, and phytosterol β-sitosterol were the dominant compounds in all water samples. The sterol abundance pattern in river water was different from that in raw sewage, indicating a more pronounced biogenic input, as well as greater impact of wastewater discharges on the composition of the suspended phase. Severe contamination of the investigated area was determined, with the Danube being more contaminated than the Sava River due to different hydrodynamic conditions leading to significantly higher sterol levels in the suspended particulate matter. It was also shown that the greater part of human/animal sterols and phytosterols present in river water samples (83.0 ± 11.9 % and 87.1 ± 15.2 %) and wastewater samples (92.1 ± 6.8 % and 95.0 ± 5.7 %) was bound to suspended material compared to the dissolved phase, emphasizing the need to consider and analyze both water phases in the tracing of steroid-based environmental pollution in order to obtain a realistic picture of steroid contamination and their fate in the aquatic environment. A high removal rate (>98 %) of coprostanol and cholesterol during wastewater treatment was determined and only the coprostanol/(coprostanol + cholestanol) ratio was found to be sensitive enough to be affected by an improvement in the quality of treated wastewater.
PB  - Elsevier B.V.
T2  - Science of the Total Environment
T1  - Steroid-based tracing of sewage-sourced pollution of river water and wastewater treatment efficiency: Dissolved and suspended water phase distribution
SP  - 157510
VL  - 846
DO  - 10.1016/j.scitotenv.2022.157510
ER  - 

@article{
author = "Jauković, Zorica and Grujić, Svetlana and Bujagić Matić, Ivana and Petković, Anđelka and Laušević, Mila",
year = "2022",
abstract = "In this work, the environmental distribution of steroid compounds and the level of sewage-derived contamination were assessed using sterol ratios in the confluence area of two major rivers in the Serbian capital, where raw sewage is discharged without any treatment. Special attention was paid to steroids partitioning between the dissolved and suspended phases of river and wastewater samples, since steroids tend to easily bind to particulate matter. The efficiency of sterol removal in two wastewater treatment plants in Serbia was also evaluated. Human/animal sterols coprostanol and cholesterol, and phytosterol β-sitosterol were the dominant compounds in all water samples. The sterol abundance pattern in river water was different from that in raw sewage, indicating a more pronounced biogenic input, as well as greater impact of wastewater discharges on the composition of the suspended phase. Severe contamination of the investigated area was determined, with the Danube being more contaminated than the Sava River due to different hydrodynamic conditions leading to significantly higher sterol levels in the suspended particulate matter. It was also shown that the greater part of human/animal sterols and phytosterols present in river water samples (83.0 ± 11.9 % and 87.1 ± 15.2 %) and wastewater samples (92.1 ± 6.8 % and 95.0 ± 5.7 %) was bound to suspended material compared to the dissolved phase, emphasizing the need to consider and analyze both water phases in the tracing of steroid-based environmental pollution in order to obtain a realistic picture of steroid contamination and their fate in the aquatic environment. A high removal rate (>98 %) of coprostanol and cholesterol during wastewater treatment was determined and only the coprostanol/(coprostanol + cholestanol) ratio was found to be sensitive enough to be affected by an improvement in the quality of treated wastewater.",
publisher = "Elsevier B.V.",
journal = "Science of the Total Environment",
title = "Steroid-based tracing of sewage-sourced pollution of river water and wastewater treatment efficiency: Dissolved and suspended water phase distribution",
pages = "157510",
volume = "846",
doi = "10.1016/j.scitotenv.2022.157510"
}

Jauković, Z., Grujić, S., Bujagić Matić, I., Petković, A.,& Laušević, M.. (2022). Steroid-based tracing of sewage-sourced pollution of river water and wastewater treatment efficiency: Dissolved and suspended water phase distribution. in Science of the Total Environment
Elsevier B.V.., 846, 157510.
https://doi.org/10.1016/j.scitotenv.2022.157510

Jauković Z, Grujić S, Bujagić Matić I, Petković A, Laušević M. Steroid-based tracing of sewage-sourced pollution of river water and wastewater treatment efficiency: Dissolved and suspended water phase distribution. in Science of the Total Environment. 2022;846:157510.
doi:10.1016/j.scitotenv.2022.157510 .

Jauković, Zorica, Grujić, Svetlana, Bujagić Matić, Ivana, Petković, Anđelka, Laušević, Mila, "Steroid-based tracing of sewage-sourced pollution of river water and wastewater treatment efficiency: Dissolved and suspended water phase distribution" in Science of the Total Environment, 846 (2022):157510,
https://doi.org/10.1016/j.scitotenv.2022.157510 . .

TY  - CHAP
AU  - Matić Bujagić, Ivana
AU  - Grujić, Svetlana
AU  - Đurkić, Tatjana
AU  - Laušević, Mila
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6053
PB  - IWA Publishing
T2  - Alluvial Aquifer Processes
T1  - Methods for trace analysis of pharmaceuticals and pesticides in water and sediment samples
DO  - 10.2166/9781789060904_0495
ER  - 

@inbook{
author = "Matić Bujagić, Ivana and Grujić, Svetlana and Đurkić, Tatjana and Laušević, Mila",
year = "2021",
publisher = "IWA Publishing",
journal = "Alluvial Aquifer Processes",
booktitle = "Methods for trace analysis of pharmaceuticals and pesticides in water and sediment samples",
doi = "10.2166/9781789060904_0495"
}

Matić Bujagić, I., Grujić, S., Đurkić, T.,& Laušević, M.. (2021). Methods for trace analysis of pharmaceuticals and pesticides in water and sediment samples. in Alluvial Aquifer Processes
IWA Publishing..
https://doi.org/10.2166/9781789060904_0495

Matić Bujagić I, Grujić S, Đurkić T, Laušević M. Methods for trace analysis of pharmaceuticals and pesticides in water and sediment samples. in Alluvial Aquifer Processes. 2021;.
doi:10.2166/9781789060904_0495 .

Matić Bujagić, Ivana, Grujić, Svetlana, Đurkić, Tatjana, Laušević, Mila, "Methods for trace analysis of pharmaceuticals and pesticides in water and sediment samples" in Alluvial Aquifer Processes (2021),
https://doi.org/10.2166/9781789060904_0495 . .

TY  - CONF
AU  - Tolić Stojadinović, Ljiljana
AU  - Gvozdić, Eleonora
AU  - Grujić, Svetlana
AU  - Antić, Nikolina
AU  - Đurkić, Tatjana
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5987
AB  - Glavni put dospevanja lekova u životnu sredinu su komunalne otpadne vode. U regionu
Beograda, otpadne vode se direktno ispuštaju u reke Savu i Dunav, što negativno utiče na kvalitet
rečne vode. Zbog svoje postojanosti i biološke aktivnosti, lekovi mogu imati veoma štetan uticaj na
živi svet u vodenoj sredini. U ovoj studiji je ispitivano prisustvo pet najčešće korišćenih
kardiovaskularnih lekova u rečnoj vodi Beograda, kao i u odgovarajućim otpadnim vodama. Za
ekstrakciju uzoraka vode korišćena je prethodno razvijena metoda za određivanje lekova u
različitim vodenim matricama. Dobijeni ekstrakti su analizirani metodom tečne hromatografije u
sprezi sa tandem masenom spektrometrijom, uz korišćenje elektrosprej jonizacione tehnike.
Rezultati su pokazali da su najčešće detektovani kardiovaskularni lekovi i u površinskim i u
otpadnim vodama bili metoprolol i bisoprolol, koji se na osnovu dosadašnjih ekotoksikoloških
istraživanja smatraju štetnim za vodene organizme.
PB  - Akademija tehničkih strukovnih studija Beograd
C3  - Šesti naučno-stručni skup Politehnika Zbornik radova
T1  - Kardiovaskularni lekovi u rečnoj vodi Beograda
EP  - 58
SP  - 55
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5987
ER  - 

@conference{
author = "Tolić Stojadinović, Ljiljana and Gvozdić, Eleonora and Grujić, Svetlana and Antić, Nikolina and Đurkić, Tatjana",
year = "2021",
abstract = "Glavni put dospevanja lekova u životnu sredinu su komunalne otpadne vode. U regionu
Beograda, otpadne vode se direktno ispuštaju u reke Savu i Dunav, što negativno utiče na kvalitet
rečne vode. Zbog svoje postojanosti i biološke aktivnosti, lekovi mogu imati veoma štetan uticaj na
živi svet u vodenoj sredini. U ovoj studiji je ispitivano prisustvo pet najčešće korišćenih
kardiovaskularnih lekova u rečnoj vodi Beograda, kao i u odgovarajućim otpadnim vodama. Za
ekstrakciju uzoraka vode korišćena je prethodno razvijena metoda za određivanje lekova u
različitim vodenim matricama. Dobijeni ekstrakti su analizirani metodom tečne hromatografije u
sprezi sa tandem masenom spektrometrijom, uz korišćenje elektrosprej jonizacione tehnike.
Rezultati su pokazali da su najčešće detektovani kardiovaskularni lekovi i u površinskim i u
otpadnim vodama bili metoprolol i bisoprolol, koji se na osnovu dosadašnjih ekotoksikoloških
istraživanja smatraju štetnim za vodene organizme.",
publisher = "Akademija tehničkih strukovnih studija Beograd",
journal = "Šesti naučno-stručni skup Politehnika Zbornik radova",
title = "Kardiovaskularni lekovi u rečnoj vodi Beograda",
pages = "58-55",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5987"
}

Tolić Stojadinović, L., Gvozdić, E., Grujić, S., Antić, N.,& Đurkić, T.. (2021). Kardiovaskularni lekovi u rečnoj vodi Beograda. in Šesti naučno-stručni skup Politehnika Zbornik radova
Akademija tehničkih strukovnih studija Beograd., 55-58.
https://hdl.handle.net/21.15107/rcub_technorep_5987

Tolić Stojadinović L, Gvozdić E, Grujić S, Antić N, Đurkić T. Kardiovaskularni lekovi u rečnoj vodi Beograda. in Šesti naučno-stručni skup Politehnika Zbornik radova. 2021;:55-58.
https://hdl.handle.net/21.15107/rcub_technorep_5987 .

Tolić Stojadinović, Ljiljana, Gvozdić, Eleonora, Grujić, Svetlana, Antić, Nikolina, Đurkić, Tatjana, "Kardiovaskularni lekovi u rečnoj vodi Beograda" in Šesti naučno-stručni skup Politehnika Zbornik radova (2021):55-58,
https://hdl.handle.net/21.15107/rcub_technorep_5987 .

TY  - CONF
AU  - Gvozdić, Eleonora
AU  - Matić Bujagić, Ivana
AU  - Đurkić, Tatjana
AU  - Grujić, Svetlana
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5929
AB  - Artificial sweeteners have been recognized as high-priority emerging contaminants that cause great concern due to unknown environmental behavior and long-term ecotoxicological impact on water resources. Wastewater treatment plants are not designed to remove these pollutants and consequently they are continuously introduced into the aquatic environment. This paper describes investigation of four artificial sweeteners, highly abundant in urban wastewater, and their removal rate in wastewater treatment plants in Serbia, in order to assess the efficiency of the treatment to reduce their environmental inputs. For this purpose, influent and effluent wastewater samples from two treatment plants were extracted and analyzed using liquid chromatography–tandem mass spectrometry.
PB  - Belgrade : Society of Physical Chemists of Serbia
C3  - Physical Chemistry 2021 : proceedings : the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction / 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 20-24, 2021, Belgrade, Serbia
T1  - Removal efficiency of artificial sweeteners in wastewater treatment plants in Serbia
EP  - 543
SP  - 541
VL  - 2
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5929
ER  - 

@conference{
author = "Gvozdić, Eleonora and Matić Bujagić, Ivana and Đurkić, Tatjana and Grujić, Svetlana",
year = "2021",
abstract = "Artificial sweeteners have been recognized as high-priority emerging contaminants that cause great concern due to unknown environmental behavior and long-term ecotoxicological impact on water resources. Wastewater treatment plants are not designed to remove these pollutants and consequently they are continuously introduced into the aquatic environment. This paper describes investigation of four artificial sweeteners, highly abundant in urban wastewater, and their removal rate in wastewater treatment plants in Serbia, in order to assess the efficiency of the treatment to reduce their environmental inputs. For this purpose, influent and effluent wastewater samples from two treatment plants were extracted and analyzed using liquid chromatography–tandem mass spectrometry.",
publisher = "Belgrade : Society of Physical Chemists of Serbia",
journal = "Physical Chemistry 2021 : proceedings : the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction / 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 20-24, 2021, Belgrade, Serbia",
title = "Removal efficiency of artificial sweeteners in wastewater treatment plants in Serbia",
pages = "543-541",
volume = "2",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5929"
}

Gvozdić, E., Matić Bujagić, I., Đurkić, T.,& Grujić, S.. (2021). Removal efficiency of artificial sweeteners in wastewater treatment plants in Serbia. in Physical Chemistry 2021 : proceedings : the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction / 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 20-24, 2021, Belgrade, Serbia
Belgrade : Society of Physical Chemists of Serbia., 2, 541-543.
https://hdl.handle.net/21.15107/rcub_technorep_5929

Gvozdić E, Matić Bujagić I, Đurkić T, Grujić S. Removal efficiency of artificial sweeteners in wastewater treatment plants in Serbia. in Physical Chemistry 2021 : proceedings : the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction / 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 20-24, 2021, Belgrade, Serbia. 2021;2:541-543.
https://hdl.handle.net/21.15107/rcub_technorep_5929 .

Gvozdić, Eleonora, Matić Bujagić, Ivana, Đurkić, Tatjana, Grujić, Svetlana, "Removal efficiency of artificial sweeteners in wastewater treatment plants in Serbia" in Physical Chemistry 2021 : proceedings : the Conference is dedicated to the 30th Anniversary of the founding of the Society of Physical Chemists of Serbia and 100th Anniversary of Bray-Liebhafsky reaction / 15th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 20-24, 2021, Belgrade, Serbia, 2 (2021):541-543,
https://hdl.handle.net/21.15107/rcub_technorep_5929 .

TY  - CONF
AU  - Gvozdić, Eleonora
AU  - Matić Bujagić, Ivana
AU  - Đurkić, Tatjana
AU  - Grujić, Svetlana
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5928
AB  - Velika primena veštačkih zaslađivača kao aditiva u hrani, piću, lekovima i sredstvima za oralnu higijenu je dovela do akumuliranja ovih supstanci u akvatičnim ekosistemima širom sveta. Pošto je većina njih metabolički inertna i nepotpuno se uklanja u postrojenjima za prečišćavanje otpadnih voda, komunalne otpadne vode predstavljaju glavni izvor ovih jedinjenja u životnoj sredini. Njihovo ponašanje i uticaj na živi svet je uglavnom nepoznat, pa su svrstani u visoko prioritetne emergentne zagađujuće materije. Neki od njih, poput acesulfama i sukraloze, su veoma postojani u vodenoj sredini, pa se mogu koristiti kao markeri zagađenja komunalnim otpadnim vodama. U ovom radu je praćeno prisustvo najčešće korišćenih zaslađivača u Republici Srbiji (acesulfama, saharina, ciklamata, sukraloze i aspartama) u podzemnoj vodi iz dva beogradska reni bunara, kao i u reci Savi, radi procene uticaja netretiranih komunalnih otpadnih voda na vodoizvorišta, pomoću metode tečne hromatografije sa tandem masenom spektrometrijom.
AB  - The widespread use of artificial sweeteners as additives in food, beverages, medicines and oral care products has led to the accumulation of these substances in aquatic ecosystems around the world. Since most of them are metabolically inert and are incompletely eliminated in wastewater treatment plants, municipal wastewater is the main source of these compounds in the environment. Due to the limited knowledge of their environmental fate and ecotoxicity, artificial sweeteeners are recognized as high-priority emerging contaminants. Some of them, such as acesulfame and sucralose, are very persistent in the aquatic environment, so they can be used as chemical markers of municipal wastewater pollution. In this paper, the presence of the most commonly used sweeteners in the Republic of Serbia (acesulfame, saccharin, cyclamate, sucralose and aspartame) was investigated in groundwater from two Belgrade Ranney wells, as well as in the Sava River, in order to assess the impact of untreated municipal wastewater on water sources, using liquid chromatography–tandem mass spectrometry.ers as additives in food, beverages, medicines and oral care products has led to the accumulation of these substances in aquatic ecosystems around the world. Since most of them are metabolically inert and are incompletely eliminated in wastewater treatment plants, municipal wastewater is the main source of these compounds in the environment. Due to the limited knowledge of their environmental fate and ecotoxicity, artificial sweeteeners are recognized as high-priority emerging contaminants. Some of them, such as acesulfame and sucralose, are very persistent in the aquatic environment, so they can be used as chemical markers of municipal wastewater pollution. In this paper, the presence of the most commonly used sweeteners in the Republic of Serbia (acesulfame, saccharin, cyclamate, sucralose and aspartame) was investigated in groundwater from two Belgrade Ranney wells, as well as in the Sava River, in order to assess the impact of untreated municipal wastewater on water sources, using liquid chromatography–tandem mass spectrometry.
PB  - Beograd : Savez mašinskih i elektrotehničkih inženjera i tehničara Srbije (SMEITS), Društvo za procesnu tehniku
C3  - Zbornik radova / 34. Međunarodni kongres o procesnoj industriji, PROCESING '21, 3. i 4. jun 2021, Novi Sad
T1  - Veštački zaslađivači u podzemnoj vodi kao indikatori komunalnog zagađenja
T1  - Artificial sweeteners in groundwater as indicators of municipal pollution
EP  - 59
SP  - 55
DO  - 10.24094/ptk.021.34.1.55
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5928
ER  - 

@conference{
author = "Gvozdić, Eleonora and Matić Bujagić, Ivana and Đurkić, Tatjana and Grujić, Svetlana",
year = "2021",
abstract = "Velika primena veštačkih zaslađivača kao aditiva u hrani, piću, lekovima i sredstvima za oralnu higijenu je dovela do akumuliranja ovih supstanci u akvatičnim ekosistemima širom sveta. Pošto je većina njih metabolički inertna i nepotpuno se uklanja u postrojenjima za prečišćavanje otpadnih voda, komunalne otpadne vode predstavljaju glavni izvor ovih jedinjenja u životnoj sredini. Njihovo ponašanje i uticaj na živi svet je uglavnom nepoznat, pa su svrstani u visoko prioritetne emergentne zagađujuće materije. Neki od njih, poput acesulfama i sukraloze, su veoma postojani u vodenoj sredini, pa se mogu koristiti kao markeri zagađenja komunalnim otpadnim vodama. U ovom radu je praćeno prisustvo najčešće korišćenih zaslađivača u Republici Srbiji (acesulfama, saharina, ciklamata, sukraloze i aspartama) u podzemnoj vodi iz dva beogradska reni bunara, kao i u reci Savi, radi procene uticaja netretiranih komunalnih otpadnih voda na vodoizvorišta, pomoću metode tečne hromatografije sa tandem masenom spektrometrijom., The widespread use of artificial sweeteners as additives in food, beverages, medicines and oral care products has led to the accumulation of these substances in aquatic ecosystems around the world. Since most of them are metabolically inert and are incompletely eliminated in wastewater treatment plants, municipal wastewater is the main source of these compounds in the environment. Due to the limited knowledge of their environmental fate and ecotoxicity, artificial sweeteeners are recognized as high-priority emerging contaminants. Some of them, such as acesulfame and sucralose, are very persistent in the aquatic environment, so they can be used as chemical markers of municipal wastewater pollution. In this paper, the presence of the most commonly used sweeteners in the Republic of Serbia (acesulfame, saccharin, cyclamate, sucralose and aspartame) was investigated in groundwater from two Belgrade Ranney wells, as well as in the Sava River, in order to assess the impact of untreated municipal wastewater on water sources, using liquid chromatography–tandem mass spectrometry.ers as additives in food, beverages, medicines and oral care products has led to the accumulation of these substances in aquatic ecosystems around the world. Since most of them are metabolically inert and are incompletely eliminated in wastewater treatment plants, municipal wastewater is the main source of these compounds in the environment. Due to the limited knowledge of their environmental fate and ecotoxicity, artificial sweeteeners are recognized as high-priority emerging contaminants. Some of them, such as acesulfame and sucralose, are very persistent in the aquatic environment, so they can be used as chemical markers of municipal wastewater pollution. In this paper, the presence of the most commonly used sweeteners in the Republic of Serbia (acesulfame, saccharin, cyclamate, sucralose and aspartame) was investigated in groundwater from two Belgrade Ranney wells, as well as in the Sava River, in order to assess the impact of untreated municipal wastewater on water sources, using liquid chromatography–tandem mass spectrometry.",
publisher = "Beograd : Savez mašinskih i elektrotehničkih inženjera i tehničara Srbije (SMEITS), Društvo za procesnu tehniku",
journal = "Zbornik radova / 34. Međunarodni kongres o procesnoj industriji, PROCESING '21, 3. i 4. jun 2021, Novi Sad",
title = "Veštački zaslađivači u podzemnoj vodi kao indikatori komunalnog zagađenja, Artificial sweeteners in groundwater as indicators of municipal pollution",
pages = "59-55",
doi = "10.24094/ptk.021.34.1.55",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5928"
}

Gvozdić, E., Matić Bujagić, I., Đurkić, T.,& Grujić, S.. (2021). Veštački zaslađivači u podzemnoj vodi kao indikatori komunalnog zagađenja. in Zbornik radova / 34. Međunarodni kongres o procesnoj industriji, PROCESING '21, 3. i 4. jun 2021, Novi Sad
Beograd : Savez mašinskih i elektrotehničkih inženjera i tehničara Srbije (SMEITS), Društvo za procesnu tehniku., 55-59.
https://doi.org/10.24094/ptk.021.34.1.55
https://hdl.handle.net/21.15107/rcub_technorep_5928

Gvozdić E, Matić Bujagić I, Đurkić T, Grujić S. Veštački zaslađivači u podzemnoj vodi kao indikatori komunalnog zagađenja. in Zbornik radova / 34. Međunarodni kongres o procesnoj industriji, PROCESING '21, 3. i 4. jun 2021, Novi Sad. 2021;:55-59.
doi:10.24094/ptk.021.34.1.55
https://hdl.handle.net/21.15107/rcub_technorep_5928 .

Gvozdić, Eleonora, Matić Bujagić, Ivana, Đurkić, Tatjana, Grujić, Svetlana, "Veštački zaslađivači u podzemnoj vodi kao indikatori komunalnog zagađenja" in Zbornik radova / 34. Međunarodni kongres o procesnoj industriji, PROCESING '21, 3. i 4. jun 2021, Novi Sad (2021):55-59,
https://doi.org/10.24094/ptk.021.34.1.55 .,
https://hdl.handle.net/21.15107/rcub_technorep_5928 .

TY  - JOUR
AU  - Stevanović, Milena
AU  - Đošić, Marija
AU  - Janković, Ana
AU  - Kojić, Vesna
AU  - Stojanović, Jovica
AU  - Grujić, Svetlana
AU  - Matić-Bujagić, Ivana
AU  - Rhee, Kyong Yop
AU  - Mišković-Stanković, Vesna
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4839
AB  - This paper describes a promising electrophoretic deposition (EPD) approach for developing composite coatings based on chitosan with the additional components of hydroxyapatite, graphene, and gentamicin on titanium substrate. Bioactive properties were investigated in vitro by immersing the coatings in simulated body fluid (SBF) at 37 degrees C. The newly formed biomimetic layer on the top of the deposited chitosan-based coatings on Ti was confirmed by X-ray diffraction, Fourier transform infrared spectroscopy, field emission scanning electron microscopy and electrochemical measurements, while coatings' bioactivity was proved by alkaline phosphatase activity assay in MRC-5 and L929 tested cell lines. The biocompatibility towards MRC-5 and L929 cell lines was investigated by dye exclusion test (DET) implying the non-cytotoxic effect of coatings. Gentamicin release studies were monitored during 21-day by high-performance liquid chromatography coupled with mass spectrometry, indicating rapid release of gentamicin (approximate to 40%) in the first 48 h and more than 60% after 14 days.
PB  - Elsevier B.V.
T2  - Journal of Materials Research and Technology
T1  - The chitosan-based bioactive composite coating on titanium
EP  - 4474
SP  - 4461
VL  - 15
DO  - 10.1016/j.jmrt.2021.10.072
ER  - 

@article{
author = "Stevanović, Milena and Đošić, Marija and Janković, Ana and Kojić, Vesna and Stojanović, Jovica and Grujić, Svetlana and Matić-Bujagić, Ivana and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2021",
abstract = "This paper describes a promising electrophoretic deposition (EPD) approach for developing composite coatings based on chitosan with the additional components of hydroxyapatite, graphene, and gentamicin on titanium substrate. Bioactive properties were investigated in vitro by immersing the coatings in simulated body fluid (SBF) at 37 degrees C. The newly formed biomimetic layer on the top of the deposited chitosan-based coatings on Ti was confirmed by X-ray diffraction, Fourier transform infrared spectroscopy, field emission scanning electron microscopy and electrochemical measurements, while coatings' bioactivity was proved by alkaline phosphatase activity assay in MRC-5 and L929 tested cell lines. The biocompatibility towards MRC-5 and L929 cell lines was investigated by dye exclusion test (DET) implying the non-cytotoxic effect of coatings. Gentamicin release studies were monitored during 21-day by high-performance liquid chromatography coupled with mass spectrometry, indicating rapid release of gentamicin (approximate to 40%) in the first 48 h and more than 60% after 14 days.",
publisher = "Elsevier B.V.",
journal = "Journal of Materials Research and Technology",
title = "The chitosan-based bioactive composite coating on titanium",
pages = "4474-4461",
volume = "15",
doi = "10.1016/j.jmrt.2021.10.072"
}

Stevanović, M., Đošić, M., Janković, A., Kojić, V., Stojanović, J., Grujić, S., Matić-Bujagić, I., Rhee, K. Y.,& Mišković-Stanković, V.. (2021). The chitosan-based bioactive composite coating on titanium. in Journal of Materials Research and Technology
Elsevier B.V.., 15, 4461-4474.
https://doi.org/10.1016/j.jmrt.2021.10.072

Stevanović M, Đošić M, Janković A, Kojić V, Stojanović J, Grujić S, Matić-Bujagić I, Rhee KY, Mišković-Stanković V. The chitosan-based bioactive composite coating on titanium. in Journal of Materials Research and Technology. 2021;15:4461-4474.
doi:10.1016/j.jmrt.2021.10.072 .

Stevanović, Milena, Đošić, Marija, Janković, Ana, Kojić, Vesna, Stojanović, Jovica, Grujić, Svetlana, Matić-Bujagić, Ivana, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "The chitosan-based bioactive composite coating on titanium" in Journal of Materials Research and Technology, 15 (2021):4461-4474,
https://doi.org/10.1016/j.jmrt.2021.10.072 . .

TY  - CONF
AU  - Gvozdić, Eleonora
AU  - Matić Bujagić, Ivana
AU  - Tolić Stojadinović, Ljiljana
AU  - Đurkić, Tatjana
AU  - Grujić, Svetlana
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5926
AB  - Veštački zaslađivači su sintetičke supstance koje se koriste za postizanje slatkog ukusa prehrambenih proizvoda, a čija je upotreba u Republici Srbiji regulisana Pravilnikom o prehrambenim aditivima. Nakon ingestije, najveći procenat ovih jedinjenja prolazi u neizmenjenoj formi kroz ljudsko telo, i kao takva dospevaju u životnu sredinu putem komunalnih otpadnih voda. Naučna istraživanja u poslednjoj deceniji su pokazala široku rasprostranjenost veštačkih zaslađivača u površinskim i podzemnim vodama. Zbog ograničenih podataka o njihovoj toksičnosti po živi svet u vodi, kao i o ponašanju u akvatičnim ekosistemima, svrstani su u klasu emergentnih zagađujućih materija.
Ovaj rad opisuje analizu široko korišćenog zaslađivača ciklamata metodom tečne hromatografije u sprezi sa tandem masenom spektrometrijom u netretiranim otpadnim vodama Beograda radi procene prisustva i unosa ovog jedinjenja u životnu sredinu. Rezultati dobijeni analizom četiri uzorka otpadnih voda iz različitih kanalizacionih ispusta u Beogradu pokazuju prisustvo ciklamata u opsegu koncentracija od 4,3 µg L–1 do 23,2 µg L–1. S obzirom na to da Beograd ne poseduje postrojenje za preradu otpadnih voda, visoki nivoi detektovanog ciklamata ukazuju na kontinualnu kontaminaciju vodenih ekosistema u Republici Srbiji i potencijalnu opasnost po živi svet u vodi.
AB  - Artificial sweeteners are synthetic substances that are used to achieve the sweet taste of
food products, and their application in the Republic of Serbia is regulated by the national
guidelines on food additives. After ingestion, the largest percentage of these compounds passes
unchanged through the human body and reaches the environment through municipal wastewater. In
the last decade, studies have shown the widespread use of artificial sweeteners in surface and
groundwater. Due to limited data on their toxicity to wildlife in the water, as well as on their
behaviour in aquatic ecosystems, they are classified as emerging contaminants.
This paper describes the analysis of widely used sweetener cyclamate by liquid chromatography
with tandem mass spectrometry in untreated urban wastewater of Belgrade to assess the presence
and input of this compound into the environment. The results obtained by analysing four
wastewater samples from different sewage channels in Belgrade show the presence of cyclamate in
the concentration range of 4.3 µg L
–1
–23.2 µg L–1
. Since Belgrade does not have a wastewater
treatment plant, high levels of cyclamate indicate the continuous contamination of aquatic
ecosystems in Serbia and the potential danger to wildlife in the water.
PB  - Beograd : Akademija tehničkih strukovnih studija "Beograd"
C3  - Zbornik radova / Šesti naučno-stručni skup sa međnarodnim učešćem Politehnika, Beograd, 10. decembar 2021. godine
T1  - ODREĐIVANJE VEŠTAČKOG ZASLAĐIVAČA CIKLAMATA U KOMUNALNOJ OTPADNOJ VODI BEOGRADA
T1  - DETERMINATION OF ARTIFICIAL SWEETENER CYCLAMATE IN BELGRADE MUNICIPAL WASTEWATER
EP  - 48
SP  - 44
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5926
ER  - 

@conference{
author = "Gvozdić, Eleonora and Matić Bujagić, Ivana and Tolić Stojadinović, Ljiljana and Đurkić, Tatjana and Grujić, Svetlana",
year = "2021",
abstract = "Veštački zaslađivači su sintetičke supstance koje se koriste za postizanje slatkog ukusa prehrambenih proizvoda, a čija je upotreba u Republici Srbiji regulisana Pravilnikom o prehrambenim aditivima. Nakon ingestije, najveći procenat ovih jedinjenja prolazi u neizmenjenoj formi kroz ljudsko telo, i kao takva dospevaju u životnu sredinu putem komunalnih otpadnih voda. Naučna istraživanja u poslednjoj deceniji su pokazala široku rasprostranjenost veštačkih zaslađivača u površinskim i podzemnim vodama. Zbog ograničenih podataka o njihovoj toksičnosti po živi svet u vodi, kao i o ponašanju u akvatičnim ekosistemima, svrstani su u klasu emergentnih zagađujućih materija.
Ovaj rad opisuje analizu široko korišćenog zaslađivača ciklamata metodom tečne hromatografije u sprezi sa tandem masenom spektrometrijom u netretiranim otpadnim vodama Beograda radi procene prisustva i unosa ovog jedinjenja u životnu sredinu. Rezultati dobijeni analizom četiri uzorka otpadnih voda iz različitih kanalizacionih ispusta u Beogradu pokazuju prisustvo ciklamata u opsegu koncentracija od 4,3 µg L–1 do 23,2 µg L–1. S obzirom na to da Beograd ne poseduje postrojenje za preradu otpadnih voda, visoki nivoi detektovanog ciklamata ukazuju na kontinualnu kontaminaciju vodenih ekosistema u Republici Srbiji i potencijalnu opasnost po živi svet u vodi., Artificial sweeteners are synthetic substances that are used to achieve the sweet taste of
food products, and their application in the Republic of Serbia is regulated by the national
guidelines on food additives. After ingestion, the largest percentage of these compounds passes
unchanged through the human body and reaches the environment through municipal wastewater. In
the last decade, studies have shown the widespread use of artificial sweeteners in surface and
groundwater. Due to limited data on their toxicity to wildlife in the water, as well as on their
behaviour in aquatic ecosystems, they are classified as emerging contaminants.
This paper describes the analysis of widely used sweetener cyclamate by liquid chromatography
with tandem mass spectrometry in untreated urban wastewater of Belgrade to assess the presence
and input of this compound into the environment. The results obtained by analysing four
wastewater samples from different sewage channels in Belgrade show the presence of cyclamate in
the concentration range of 4.3 µg L
–1
–23.2 µg L–1
. Since Belgrade does not have a wastewater
treatment plant, high levels of cyclamate indicate the continuous contamination of aquatic
ecosystems in Serbia and the potential danger to wildlife in the water.",
publisher = "Beograd : Akademija tehničkih strukovnih studija "Beograd"",
journal = "Zbornik radova / Šesti naučno-stručni skup sa međnarodnim učešćem Politehnika, Beograd, 10. decembar 2021. godine",
title = "ODREĐIVANJE VEŠTAČKOG ZASLAĐIVAČA CIKLAMATA U KOMUNALNOJ OTPADNOJ VODI BEOGRADA, DETERMINATION OF ARTIFICIAL SWEETENER CYCLAMATE IN BELGRADE MUNICIPAL WASTEWATER",
pages = "48-44",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5926"
}

Gvozdić, E., Matić Bujagić, I., Tolić Stojadinović, L., Đurkić, T.,& Grujić, S.. (2021). ODREĐIVANJE VEŠTAČKOG ZASLAĐIVAČA CIKLAMATA U KOMUNALNOJ OTPADNOJ VODI BEOGRADA. in Zbornik radova / Šesti naučno-stručni skup sa međnarodnim učešćem Politehnika, Beograd, 10. decembar 2021. godine
Beograd : Akademija tehničkih strukovnih studija "Beograd"., 44-48.
https://hdl.handle.net/21.15107/rcub_technorep_5926

Gvozdić E, Matić Bujagić I, Tolić Stojadinović L, Đurkić T, Grujić S. ODREĐIVANJE VEŠTAČKOG ZASLAĐIVAČA CIKLAMATA U KOMUNALNOJ OTPADNOJ VODI BEOGRADA. in Zbornik radova / Šesti naučno-stručni skup sa međnarodnim učešćem Politehnika, Beograd, 10. decembar 2021. godine. 2021;:44-48.
https://hdl.handle.net/21.15107/rcub_technorep_5926 .

Gvozdić, Eleonora, Matić Bujagić, Ivana, Tolić Stojadinović, Ljiljana, Đurkić, Tatjana, Grujić, Svetlana, "ODREĐIVANJE VEŠTAČKOG ZASLAĐIVAČA CIKLAMATA U KOMUNALNOJ OTPADNOJ VODI BEOGRADA" in Zbornik radova / Šesti naučno-stručni skup sa međnarodnim učešćem Politehnika, Beograd, 10. decembar 2021. godine (2021):44-48,
https://hdl.handle.net/21.15107/rcub_technorep_5926 .

TY  - CONF
AU  - Tolić Stojadinović, Ljiljana
AU  - Grujić, Svetlana
AU  - Antić, Nikolina
AU  - Đurkić, Tatjana
PY  - 2021
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5983
AB  - In the city of Belgrade, raw sewage is discharged directly into the Sava and the Danube rivers affecting the quality of river water. To determine the level of this impact, eight frequently used and detected pharmaceuticals were selected for the study. A previously developed method for analysis of pharmaceuticals in different water matrices was used. Sample extracts were analyzed by liquid chromatography-tandem mass spectrometry, using the electrospray ionization technique. The most commonly detected analytes in both municipal wastewater and surface water were carbamazepine, known for its high environmental stability, and diclofenac, known as having high acute ecotoxicity. The dilution effect, noted for most of the detected drugs, was not as pronounced with diclofenac, indicating a higher risk for aquatic organisms.
PB  - Society of Physical Chemists of Serbia
C3  - Physical Chemistry 2021
T1  - Impact of pharmaceutical levels in untreated wastewater on Belgrade river water quality
EP  - 571
SP  - 569
VL  - II
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5983
ER  - 

@conference{
author = "Tolić Stojadinović, Ljiljana and Grujić, Svetlana and Antić, Nikolina and Đurkić, Tatjana",
year = "2021",
abstract = "In the city of Belgrade, raw sewage is discharged directly into the Sava and the Danube rivers affecting the quality of river water. To determine the level of this impact, eight frequently used and detected pharmaceuticals were selected for the study. A previously developed method for analysis of pharmaceuticals in different water matrices was used. Sample extracts were analyzed by liquid chromatography-tandem mass spectrometry, using the electrospray ionization technique. The most commonly detected analytes in both municipal wastewater and surface water were carbamazepine, known for its high environmental stability, and diclofenac, known as having high acute ecotoxicity. The dilution effect, noted for most of the detected drugs, was not as pronounced with diclofenac, indicating a higher risk for aquatic organisms.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical Chemistry 2021",
title = "Impact of pharmaceutical levels in untreated wastewater on Belgrade river water quality",
pages = "571-569",
volume = "II",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5983"
}

Tolić Stojadinović, L., Grujić, S., Antić, N.,& Đurkić, T.. (2021). Impact of pharmaceutical levels in untreated wastewater on Belgrade river water quality. in Physical Chemistry 2021
Society of Physical Chemists of Serbia., II, 569-571.
https://hdl.handle.net/21.15107/rcub_technorep_5983

Tolić Stojadinović L, Grujić S, Antić N, Đurkić T. Impact of pharmaceutical levels in untreated wastewater on Belgrade river water quality. in Physical Chemistry 2021. 2021;II:569-571.
https://hdl.handle.net/21.15107/rcub_technorep_5983 .

Tolić Stojadinović, Ljiljana, Grujić, Svetlana, Antić, Nikolina, Đurkić, Tatjana, "Impact of pharmaceutical levels in untreated wastewater on Belgrade river water quality" in Physical Chemistry 2021, II (2021):569-571,
https://hdl.handle.net/21.15107/rcub_technorep_5983 .

TY  - JOUR
AU  - Gvozdić, Eleonora
AU  - Matić Bujagić, Ivana
AU  - Đurkić, Tatjana
AU  - Grujić, Svetlana
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4395
PB  - Elsevier Inc.
T2  - Microchemical Journal
T1  - Trace analysis of artificial sweeteners in environmental waters, wastewater and river sediments by liquid chromatography-tandem mass spectrometry
SP  - 105071
VL  - 157
DO  - 10.1016/j.microc.2020.105071
ER  - 

@article{
author = "Gvozdić, Eleonora and Matić Bujagić, Ivana and Đurkić, Tatjana and Grujić, Svetlana",
year = "2020",
publisher = "Elsevier Inc.",
journal = "Microchemical Journal",
title = "Trace analysis of artificial sweeteners in environmental waters, wastewater and river sediments by liquid chromatography-tandem mass spectrometry",
pages = "105071",
volume = "157",
doi = "10.1016/j.microc.2020.105071"
}

Gvozdić, E., Matić Bujagić, I., Đurkić, T.,& Grujić, S.. (2020). Trace analysis of artificial sweeteners in environmental waters, wastewater and river sediments by liquid chromatography-tandem mass spectrometry. in Microchemical Journal
Elsevier Inc.., 157, 105071.
https://doi.org/10.1016/j.microc.2020.105071

Gvozdić E, Matić Bujagić I, Đurkić T, Grujić S. Trace analysis of artificial sweeteners in environmental waters, wastewater and river sediments by liquid chromatography-tandem mass spectrometry. in Microchemical Journal. 2020;157:105071.
doi:10.1016/j.microc.2020.105071 .

Gvozdić, Eleonora, Matić Bujagić, Ivana, Đurkić, Tatjana, Grujić, Svetlana, "Trace analysis of artificial sweeteners in environmental waters, wastewater and river sediments by liquid chromatography-tandem mass spectrometry" in Microchemical Journal, 157 (2020):105071,
https://doi.org/10.1016/j.microc.2020.105071 . .

TY  - JOUR
AU  - Stevanović, Milena
AU  - Đošić, Marija
AU  - Janković, Ana
AU  - Nešović, Katarina
AU  - Kojić, Vesna
AU  - Stojanović, Jovica
AU  - Grujić, Svetlana
AU  - Matić-Bujagić, Ivana
AU  - Rhee, Kyong Yop
AU  - Mišković-Stanković, Vesna
PY  - 2020
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4498
AB  - The electrophoretic deposition process (EPD) was utilized to produce bioactive hydroxyapatite/chitosan (HAP/CS) and hydroxyapatite/chitosan/gentamicin (HAP/CS/Gent) coatings on titanium. The bioactivity of newly synthesized composite coatings was investigated in the simulated body fluid (SBF) and examined by X-ray diffraction, Fourier transform infrared spectroscopy, and field emission scanning electron microscopy. The obtained results revealed carbonate-substituted hydroxyapatite after immersion in SBF, emphasizing the similarity of the biomimetically grown HAP with the naturally occurring apatite in the bone. The formation of biomimetic HAP was confirmed by electrochemical impedance spectroscopy and polarization measurements, through the decrease in corrosion current density and coating capacitance values after 28-day immersion in SBF. The osseointegration ability was further validated by measuring the alkaline phosphatase activity (ALP) indicating the favorable osseopromotive properties of deposited coatings (significant increase in ALP levels for both HAP/CS (3.206 U mL(-1)) and HAP/CS/Gent (4.039 U mL(-1)) coatings, compared to the control (0.900 U mL(-1))). Drug-release kinetics was investigated in deionized water at 37 degrees C by high-performance liquid chromatography coupled with mass spectrometry. Release profiles revealed the beneficial "burst-release effect" (similar to 21% of gentamicin released in the first 48 h) as a potentially promising solution against the biofilm formation in the initial period. When tested against human and mice fibroblast cells (MRC-5 and L929), both composite coatings showed a noncytotoxic effect (viability  gt 85%), providing a promising basis for further medical application trials.
PB  - Amer Chemical Soc, Washington
T2  - ACS Omega
T1  - Assessing the Bioactivity of Gentamicin-Preloaded Hydroxyapatite/Chitosan Composite Coating on Titanium Substrate
EP  - 15445
IS  - 25
SP  - 15433
VL  - 5
DO  - 10.1021/acsomega.0c01583
ER  - 

@article{
author = "Stevanović, Milena and Đošić, Marija and Janković, Ana and Nešović, Katarina and Kojić, Vesna and Stojanović, Jovica and Grujić, Svetlana and Matić-Bujagić, Ivana and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2020",
abstract = "The electrophoretic deposition process (EPD) was utilized to produce bioactive hydroxyapatite/chitosan (HAP/CS) and hydroxyapatite/chitosan/gentamicin (HAP/CS/Gent) coatings on titanium. The bioactivity of newly synthesized composite coatings was investigated in the simulated body fluid (SBF) and examined by X-ray diffraction, Fourier transform infrared spectroscopy, and field emission scanning electron microscopy. The obtained results revealed carbonate-substituted hydroxyapatite after immersion in SBF, emphasizing the similarity of the biomimetically grown HAP with the naturally occurring apatite in the bone. The formation of biomimetic HAP was confirmed by electrochemical impedance spectroscopy and polarization measurements, through the decrease in corrosion current density and coating capacitance values after 28-day immersion in SBF. The osseointegration ability was further validated by measuring the alkaline phosphatase activity (ALP) indicating the favorable osseopromotive properties of deposited coatings (significant increase in ALP levels for both HAP/CS (3.206 U mL(-1)) and HAP/CS/Gent (4.039 U mL(-1)) coatings, compared to the control (0.900 U mL(-1))). Drug-release kinetics was investigated in deionized water at 37 degrees C by high-performance liquid chromatography coupled with mass spectrometry. Release profiles revealed the beneficial "burst-release effect" (similar to 21% of gentamicin released in the first 48 h) as a potentially promising solution against the biofilm formation in the initial period. When tested against human and mice fibroblast cells (MRC-5 and L929), both composite coatings showed a noncytotoxic effect (viability  gt 85%), providing a promising basis for further medical application trials.",
publisher = "Amer Chemical Soc, Washington",
journal = "ACS Omega",
title = "Assessing the Bioactivity of Gentamicin-Preloaded Hydroxyapatite/Chitosan Composite Coating on Titanium Substrate",
pages = "15445-15433",
number = "25",
volume = "5",
doi = "10.1021/acsomega.0c01583"
}

Stevanović, M., Đošić, M., Janković, A., Nešović, K., Kojić, V., Stojanović, J., Grujić, S., Matić-Bujagić, I., Rhee, K. Y.,& Mišković-Stanković, V.. (2020). Assessing the Bioactivity of Gentamicin-Preloaded Hydroxyapatite/Chitosan Composite Coating on Titanium Substrate. in ACS Omega
Amer Chemical Soc, Washington., 5(25), 15433-15445.
https://doi.org/10.1021/acsomega.0c01583

Stevanović M, Đošić M, Janković A, Nešović K, Kojić V, Stojanović J, Grujić S, Matić-Bujagić I, Rhee KY, Mišković-Stanković V. Assessing the Bioactivity of Gentamicin-Preloaded Hydroxyapatite/Chitosan Composite Coating on Titanium Substrate. in ACS Omega. 2020;5(25):15433-15445.
doi:10.1021/acsomega.0c01583 .

Stevanović, Milena, Đošić, Marija, Janković, Ana, Nešović, Katarina, Kojić, Vesna, Stojanović, Jovica, Grujić, Svetlana, Matić-Bujagić, Ivana, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "Assessing the Bioactivity of Gentamicin-Preloaded Hydroxyapatite/Chitosan Composite Coating on Titanium Substrate" in ACS Omega, 5, no. 25 (2020):15433-15445,
https://doi.org/10.1021/acsomega.0c01583 . .

TY  - CONF
AU  - Gvozdić, Eleonora
AU  - Matić Bujagić, Ivana
AU  - Đurkić, Tatjana
AU  - Grujić, Svetlana
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5935
AB  - Široka primena veštačkih zaslađivača u prehrambenoj i farmaceutskoj industriji počela je početkom osamdesetih godina prošlog veka. Većina ovih jedinjenja se ne metaboliše u ljudskom telu i izlučuje se uglavnom nepromenjena. Glavni izvor veštačkih zaslađivača u životnoj sredini predstavljaju komunalne otpadne vode. Zbog ograničenih podataka o njihovoj ekotoksičnosti i ponašanju u životnoj sredini, svrstani su u klasu emergentnih zagađujućih materija. Dosadašnja istraživanja su pokazala široku rasprostranjenost ovih jedinjenja u površinskim i podzemnim vodama.
 U ovom radu je razvijena i optimizovana metoda pripreme uzoraka otpadne vode ekstrakcijom na čvrstoj fazi za analizu veštačkog zaslađivača saharina. Izvršen je odabir optimalnog sorbenta, pH vrednosti i zapremine uzorka vode, kao i rastvarača za eluiranje saharina sa pakovanja kolone. Dobijeni ekstrakti su analizirani metodom tečne hromatografije sa tandem masenom spektrometrijom. Razvijena metoda je primenjena na uzorke otpadnih voda iz tri kanalizaciona ispusta u Beogradu i okolini. Detektovane koncentracije saharina su bile u opsegu od 2,9 µg L–1 do 13,5 µg L–1.
AB  - The widespread use of artificial sweeteners in the food and pharmaceutical industry
started at the beginning of the 1980s. Most of these compounds are not metabolized in human body
and are excreted mostly unchanged. Communal wastewater is the main source of artificial
sweeteners in the environment. Due to limited data on their ecotoxicity and fate in the environment,
they are classified as emerging pollutants. Previous research has shown the wide distribution of
these compounds in surface and ground water. In this paper, the method of preparation of
wastewater samples was developed and optimized using the solid-phase extraction for the analysis
of artificial sweetener saccharin. The sorbent type, the pH and the volume of the water sample, as
well as the elution solvent were tested in the sample preparation optimization. The obtained
extracts were analyzed by liquid chromatography–tandem mass spectrometry. The developed
method was applied to wastewater samples collected from three sewage discharges in Belgrade and
the surroundings. The detected concentrations of saccharin were in the range from 2.9 μg L–1
 to
13.5 μg L–1
.
PB  - Beograd : Beogradska politehnika
C3  - Zbornik radova / Peti naučno-stručni skup Politehnika 5, Beograd, 13. decembar 2019.godine
T1  - Određivanje veštačkog zaslađivača saharina u uzorcima otpadne vode
T1  - Determination of artificial sweetener saccharin in wastewater samples
EP  - 224
SP  - 220
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5935
ER  - 

@conference{
author = "Gvozdić, Eleonora and Matić Bujagić, Ivana and Đurkić, Tatjana and Grujić, Svetlana",
year = "2019",
abstract = "Široka primena veštačkih zaslađivača u prehrambenoj i farmaceutskoj industriji počela je početkom osamdesetih godina prošlog veka. Većina ovih jedinjenja se ne metaboliše u ljudskom telu i izlučuje se uglavnom nepromenjena. Glavni izvor veštačkih zaslađivača u životnoj sredini predstavljaju komunalne otpadne vode. Zbog ograničenih podataka o njihovoj ekotoksičnosti i ponašanju u životnoj sredini, svrstani su u klasu emergentnih zagađujućih materija. Dosadašnja istraživanja su pokazala široku rasprostranjenost ovih jedinjenja u površinskim i podzemnim vodama.
 U ovom radu je razvijena i optimizovana metoda pripreme uzoraka otpadne vode ekstrakcijom na čvrstoj fazi za analizu veštačkog zaslađivača saharina. Izvršen je odabir optimalnog sorbenta, pH vrednosti i zapremine uzorka vode, kao i rastvarača za eluiranje saharina sa pakovanja kolone. Dobijeni ekstrakti su analizirani metodom tečne hromatografije sa tandem masenom spektrometrijom. Razvijena metoda je primenjena na uzorke otpadnih voda iz tri kanalizaciona ispusta u Beogradu i okolini. Detektovane koncentracije saharina su bile u opsegu od 2,9 µg L–1 do 13,5 µg L–1., The widespread use of artificial sweeteners in the food and pharmaceutical industry
started at the beginning of the 1980s. Most of these compounds are not metabolized in human body
and are excreted mostly unchanged. Communal wastewater is the main source of artificial
sweeteners in the environment. Due to limited data on their ecotoxicity and fate in the environment,
they are classified as emerging pollutants. Previous research has shown the wide distribution of
these compounds in surface and ground water. In this paper, the method of preparation of
wastewater samples was developed and optimized using the solid-phase extraction for the analysis
of artificial sweetener saccharin. The sorbent type, the pH and the volume of the water sample, as
well as the elution solvent were tested in the sample preparation optimization. The obtained
extracts were analyzed by liquid chromatography–tandem mass spectrometry. The developed
method was applied to wastewater samples collected from three sewage discharges in Belgrade and
the surroundings. The detected concentrations of saccharin were in the range from 2.9 μg L–1
 to
13.5 μg L–1
.",
publisher = "Beograd : Beogradska politehnika",
journal = "Zbornik radova / Peti naučno-stručni skup Politehnika 5, Beograd, 13. decembar 2019.godine",
title = "Određivanje veštačkog zaslađivača saharina u uzorcima otpadne vode, Determination of artificial sweetener saccharin in wastewater samples",
pages = "224-220",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5935"
}

Gvozdić, E., Matić Bujagić, I., Đurkić, T.,& Grujić, S.. (2019). Određivanje veštačkog zaslađivača saharina u uzorcima otpadne vode. in Zbornik radova / Peti naučno-stručni skup Politehnika 5, Beograd, 13. decembar 2019.godine
Beograd : Beogradska politehnika., 220-224.
https://hdl.handle.net/21.15107/rcub_technorep_5935

Gvozdić E, Matić Bujagić I, Đurkić T, Grujić S. Određivanje veštačkog zaslađivača saharina u uzorcima otpadne vode. in Zbornik radova / Peti naučno-stručni skup Politehnika 5, Beograd, 13. decembar 2019.godine. 2019;:220-224.
https://hdl.handle.net/21.15107/rcub_technorep_5935 .

Gvozdić, Eleonora, Matić Bujagić, Ivana, Đurkić, Tatjana, Grujić, Svetlana, "Određivanje veštačkog zaslađivača saharina u uzorcima otpadne vode" in Zbornik radova / Peti naučno-stručni skup Politehnika 5, Beograd, 13. decembar 2019.godine (2019):220-224,
https://hdl.handle.net/21.15107/rcub_technorep_5935 .

TY  - CONF
AU  - Gvozdić, Eleonora Ž.
AU  - Matić Bujagić, Ivana V.
AU  - Grujić, Svetlana D.
AU  - Đurkić, Tatjana M.
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5936
AB  - Veštački zaslađivači predstavljaju emergentne zagađujuće materije u životnoj sredini. Decenijama se koriste kao aditivi u ishrani i farmaceutskim proizvodima zbog čega su široko rasprostranjeni u prirodnim vodama usled nepotpunog prečišćavanja otpadnih voda. Međutim, pojedini zaslađivači, poput neotama, poseduju visok afinitet za adsorpciju na sedimentu prilikom raspodele u sistemu voda-sediment. Zbog toga je u ovom radu razvijen i optimizovan postupak pripreme uzoraka sedimenata metodom ultrazvučne ekstrakcije za određivanje tragova neotama. Nakon predtretmana, rečni sedimenti (2 g) su ekstrahovani pomoću dihlormetana (3  5 cm3) u ultrazvučnom kupatilu u trajanju od 3  5 min. Dobijeni ekstrakti su analizirani metodom tečne hromatografije sa tandem masenom spektrometrijom. Razvijena metoda je primenjena na uzorke sedimenata iz nekoliko reka u Srbiji – Tise, Morave, Save i Dunava. Po prvi put, dobijeni su podaci o stepenu zagađenosti sedimenata u Srbiji veštačkim zaslađivačem neotamom, detektovanom u koncentracijama od 2 do 56 µg g–1.
AB  - Artificial sweeteners are known as emerging pollutants in the environment. For decades
they have been used as food and pharmaceutical additives, which is why they are
widespread in natural waters, due to incomplete wastewater treatment. However, some
sweeteners, such as neotame, possess a high sorption affinity and partition to sediment in
the water-sediment system. Therefore, in this paper, a method for the sediment sample
preparation using an ultrasonic extraction for determination of neotame traces was
developed and optimized. After pre-treatment, river sediments (2 g) were extracted using
dichloromethane (3  5 cm3
) in an ultrasonic bath for 3  5 min. The obtained extracts were
analyzed by liquid chromatography with tandem mass spectrometry. The developed
method was applied to sediment samples from several rivers in Serbia – the Tisza, the
Morava, the Sava and the Danube. For the first time, data on the contamination level of
sediments in Serbia with artificial sweetener neotame (in the concentration range from 2
to 48 µg g
–1
) were obtained.
PB  - Beograd : Srpsko hemijsko društvo
C3  - Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019
T1  - Određivanje veštačkog zaslađivača neotama u rečnim sedimentima
T1  - Determination of artificial sweetener neotame in river sediments
SP  - 11
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5936
ER  - 

@conference{
author = "Gvozdić, Eleonora Ž. and Matić Bujagić, Ivana V. and Grujić, Svetlana D. and Đurkić, Tatjana M.",
year = "2019",
abstract = "Veštački zaslađivači predstavljaju emergentne zagađujuće materije u životnoj sredini. Decenijama se koriste kao aditivi u ishrani i farmaceutskim proizvodima zbog čega su široko rasprostranjeni u prirodnim vodama usled nepotpunog prečišćavanja otpadnih voda. Međutim, pojedini zaslađivači, poput neotama, poseduju visok afinitet za adsorpciju na sedimentu prilikom raspodele u sistemu voda-sediment. Zbog toga je u ovom radu razvijen i optimizovan postupak pripreme uzoraka sedimenata metodom ultrazvučne ekstrakcije za određivanje tragova neotama. Nakon predtretmana, rečni sedimenti (2 g) su ekstrahovani pomoću dihlormetana (3  5 cm3) u ultrazvučnom kupatilu u trajanju od 3  5 min. Dobijeni ekstrakti su analizirani metodom tečne hromatografije sa tandem masenom spektrometrijom. Razvijena metoda je primenjena na uzorke sedimenata iz nekoliko reka u Srbiji – Tise, Morave, Save i Dunava. Po prvi put, dobijeni su podaci o stepenu zagađenosti sedimenata u Srbiji veštačkim zaslađivačem neotamom, detektovanom u koncentracijama od 2 do 56 µg g–1., Artificial sweeteners are known as emerging pollutants in the environment. For decades
they have been used as food and pharmaceutical additives, which is why they are
widespread in natural waters, due to incomplete wastewater treatment. However, some
sweeteners, such as neotame, possess a high sorption affinity and partition to sediment in
the water-sediment system. Therefore, in this paper, a method for the sediment sample
preparation using an ultrasonic extraction for determination of neotame traces was
developed and optimized. After pre-treatment, river sediments (2 g) were extracted using
dichloromethane (3  5 cm3
) in an ultrasonic bath for 3  5 min. The obtained extracts were
analyzed by liquid chromatography with tandem mass spectrometry. The developed
method was applied to sediment samples from several rivers in Serbia – the Tisza, the
Morava, the Sava and the Danube. For the first time, data on the contamination level of
sediments in Serbia with artificial sweetener neotame (in the concentration range from 2
to 48 µg g
–1
) were obtained.",
publisher = "Beograd : Srpsko hemijsko društvo",
journal = "Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019",
title = "Određivanje veštačkog zaslađivača neotama u rečnim sedimentima, Determination of artificial sweetener neotame in river sediments",
pages = "11",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5936"
}

Gvozdić, E. Ž., Matić Bujagić, I. V., Grujić, S. D.,& Đurkić, T. M.. (2019). Određivanje veštačkog zaslađivača neotama u rečnim sedimentima. in Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019
Beograd : Srpsko hemijsko društvo., 11.
https://hdl.handle.net/21.15107/rcub_technorep_5936

Gvozdić EŽ, Matić Bujagić IV, Grujić SD, Đurkić TM. Određivanje veštačkog zaslađivača neotama u rečnim sedimentima. in Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019. 2019;:11.
https://hdl.handle.net/21.15107/rcub_technorep_5936 .

Gvozdić, Eleonora Ž., Matić Bujagić, Ivana V., Grujić, Svetlana D., Đurkić, Tatjana M., "Određivanje veštačkog zaslađivača neotama u rečnim sedimentima" in Kratki izvodi radova / 56. savetovanje Srpskog hemijskog društva , Niš 7. i 8. juni 2019 (2019):11,
https://hdl.handle.net/21.15107/rcub_technorep_5936 .

TY  - CONF
AU  - Gvozdić, Eleonora Ž.
AU  - Matić Bujagić, Ivana V.
AU  - Đurkić, Tatjana M.
AU  - Grujić, Svetlana D.
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5937
AB  - Artificial sweeteners are used as sugar substitutes in food and beverages which are regulated by national guidelines on food additives (Regulation No. 53/2018)1. After decades of application, their widespread occurrence in environment has been confirmed2. Furthermore, artificial sweeteners are recognized as emerging pollutants due to their ecotoxicity and limited knowledge on environmental fate. Some sweeteners, as aspartame, possess a high sorption affinity and partition to sediment in the water-sediment system. 
In this paper, the presence of aspartame was investigated in sediments of four rivers in Serbia – the Tisza, the Morava, the Sava and the Danube. Analysis of sediment samples was performed by using an ultrasonic extraction as preparation method. The obtained extracts were analyzed by liquid chromatography with tandem mass spectrometry (LC–MS/MS). Aspartame was found in all investigated river sediments in the concentration range from 117 to 568 ng g–1. Data on the contamination levels of sediments in Serbia indicate potentially harmful effects of aspartame on benthic organisms.
PB  - Belgrade : Serbian Chemical Society
C3  - Book of abstracts / Seventh Conference of the Young Chemists of Serbia, Belgrade, 2nd November 2019
T1  - Traces of aspartame in river sediments
SP  - 64
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5937
ER  - 

@conference{
author = "Gvozdić, Eleonora Ž. and Matić Bujagić, Ivana V. and Đurkić, Tatjana M. and Grujić, Svetlana D.",
year = "2019",
abstract = "Artificial sweeteners are used as sugar substitutes in food and beverages which are regulated by national guidelines on food additives (Regulation No. 53/2018)1. After decades of application, their widespread occurrence in environment has been confirmed2. Furthermore, artificial sweeteners are recognized as emerging pollutants due to their ecotoxicity and limited knowledge on environmental fate. Some sweeteners, as aspartame, possess a high sorption affinity and partition to sediment in the water-sediment system. 
In this paper, the presence of aspartame was investigated in sediments of four rivers in Serbia – the Tisza, the Morava, the Sava and the Danube. Analysis of sediment samples was performed by using an ultrasonic extraction as preparation method. The obtained extracts were analyzed by liquid chromatography with tandem mass spectrometry (LC–MS/MS). Aspartame was found in all investigated river sediments in the concentration range from 117 to 568 ng g–1. Data on the contamination levels of sediments in Serbia indicate potentially harmful effects of aspartame on benthic organisms.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Book of abstracts / Seventh Conference of the Young Chemists of Serbia, Belgrade, 2nd November 2019",
title = "Traces of aspartame in river sediments",
pages = "64",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5937"
}

Gvozdić, E. Ž., Matić Bujagić, I. V., Đurkić, T. M.,& Grujić, S. D.. (2019). Traces of aspartame in river sediments. in Book of abstracts / Seventh Conference of the Young Chemists of Serbia, Belgrade, 2nd November 2019
Belgrade : Serbian Chemical Society., 64.
https://hdl.handle.net/21.15107/rcub_technorep_5937

Gvozdić EŽ, Matić Bujagić IV, Đurkić TM, Grujić SD. Traces of aspartame in river sediments. in Book of abstracts / Seventh Conference of the Young Chemists of Serbia, Belgrade, 2nd November 2019. 2019;:64.
https://hdl.handle.net/21.15107/rcub_technorep_5937 .

Gvozdić, Eleonora Ž., Matić Bujagić, Ivana V., Đurkić, Tatjana M., Grujić, Svetlana D., "Traces of aspartame in river sediments" in Book of abstracts / Seventh Conference of the Young Chemists of Serbia, Belgrade, 2nd November 2019 (2019):64,
https://hdl.handle.net/21.15107/rcub_technorep_5937 .

TY  - JOUR
AU  - Matić-Bujagić, Ivana
AU  - Grujić, Svetlana
AU  - Laušević, Mila
AU  - Hofmann, Thilo
AU  - Micić, Vesna
PY  - 2019
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4180
AB  - The Iron Gate I Reservoir is the largest impoundment on the Danube River. It retains  gt 50% of the incoming total suspended solids load and the associated organic contaminants. In the sediment core of the Iron Gate I Reservoir we report the presence and fate of four classes of emerging contaminants (pharmaceuticals, pesticides, steroids and perfluorinated compounds), predominantly not covered by the EU monitoring programs, but considered as future candidates. Based on contaminant's partitioning behavior in the water/sediment system and the suspected ecotoxicological potential asserted from the literature data, the risk of recorded concentrations for sediment-dwelling organisms was discussed. The high anticipated risk was associated with antibiotics sulfamethoxazole and erythromycin, and pesticides linuron and carbendazim (banned in the EU, but still approved for use in the investigated area) and malathion. This indicated the need for better control of release of these compounds into the river, and implied their inclusion in future regular monitoring. Higher concentrations of pharmaceuticals and most pesticides and sterols were recorded in the fragment of allochthonous coarser sediment, assumed to have entered the reservoir during a high discharge event. Only one perfluorinated compound was recorded in the upper part of the sediment core. The vertical concentration profiles of pesticides propazine and malathion indicated their uniform source, most likely atmospheric transport and deposition of particles deriving from agricultural land.
PB  - Elsevier, Amsterdam
T2  - Science of the Total Environment
T1  - Emerging contaminants in sediment core from the Iron Gate I Reservoir on the Danube River
EP  - 87
SP  - 77
VL  - 662
DO  - 10.1016/j.scitotenv.2019.01.205
ER  - 

@article{
author = "Matić-Bujagić, Ivana and Grujić, Svetlana and Laušević, Mila and Hofmann, Thilo and Micić, Vesna",
year = "2019",
abstract = "The Iron Gate I Reservoir is the largest impoundment on the Danube River. It retains  gt 50% of the incoming total suspended solids load and the associated organic contaminants. In the sediment core of the Iron Gate I Reservoir we report the presence and fate of four classes of emerging contaminants (pharmaceuticals, pesticides, steroids and perfluorinated compounds), predominantly not covered by the EU monitoring programs, but considered as future candidates. Based on contaminant's partitioning behavior in the water/sediment system and the suspected ecotoxicological potential asserted from the literature data, the risk of recorded concentrations for sediment-dwelling organisms was discussed. The high anticipated risk was associated with antibiotics sulfamethoxazole and erythromycin, and pesticides linuron and carbendazim (banned in the EU, but still approved for use in the investigated area) and malathion. This indicated the need for better control of release of these compounds into the river, and implied their inclusion in future regular monitoring. Higher concentrations of pharmaceuticals and most pesticides and sterols were recorded in the fragment of allochthonous coarser sediment, assumed to have entered the reservoir during a high discharge event. Only one perfluorinated compound was recorded in the upper part of the sediment core. The vertical concentration profiles of pesticides propazine and malathion indicated their uniform source, most likely atmospheric transport and deposition of particles deriving from agricultural land.",
publisher = "Elsevier, Amsterdam",
journal = "Science of the Total Environment",
title = "Emerging contaminants in sediment core from the Iron Gate I Reservoir on the Danube River",
pages = "87-77",
volume = "662",
doi = "10.1016/j.scitotenv.2019.01.205"
}

Matić-Bujagić, I., Grujić, S., Laušević, M., Hofmann, T.,& Micić, V.. (2019). Emerging contaminants in sediment core from the Iron Gate I Reservoir on the Danube River. in Science of the Total Environment
Elsevier, Amsterdam., 662, 77-87.
https://doi.org/10.1016/j.scitotenv.2019.01.205

Matić-Bujagić I, Grujić S, Laušević M, Hofmann T, Micić V. Emerging contaminants in sediment core from the Iron Gate I Reservoir on the Danube River. in Science of the Total Environment. 2019;662:77-87.
doi:10.1016/j.scitotenv.2019.01.205 .

Matić-Bujagić, Ivana, Grujić, Svetlana, Laušević, Mila, Hofmann, Thilo, Micić, Vesna, "Emerging contaminants in sediment core from the Iron Gate I Reservoir on the Danube River" in Science of the Total Environment, 662 (2019):77-87,
https://doi.org/10.1016/j.scitotenv.2019.01.205 . .

TY  - CONF
AU  - Gvozdić, Eleonora
AU  - Matić Bujagić, Ivana
AU  - Grujić, Svetlana
AU  - Đurkić, Tatjana
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5944
AB  - U ovom radu su prikazani razvoj i optimizacija tečno-hromatografske metode za analizu sedam odabranih veštačkih zaslađivača, sa ciljem optimalnog hromatografskog razdvajanja analita u što kraćem vremenskom periodu, u okviru LC-MS/MS analize.
PB  - Beograd : Srpsko hemijsko društvo
C3  - Knjiga izvoda / 8. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, Kruševac 30. maj - 1. jun 2018
T1  - Razvoj hromatografske metode za određivanje tragova veštačkih zaslađivača u vodi
T1  - Development of chromatografic method for trace determination of artificial
sweeteners in water
EP  - 168
SP  - 167
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5944
ER  - 

@conference{
author = "Gvozdić, Eleonora and Matić Bujagić, Ivana and Grujić, Svetlana and Đurkić, Tatjana",
year = "2018",
abstract = "U ovom radu su prikazani razvoj i optimizacija tečno-hromatografske metode za analizu sedam odabranih veštačkih zaslađivača, sa ciljem optimalnog hromatografskog razdvajanja analita u što kraćem vremenskom periodu, u okviru LC-MS/MS analize.",
publisher = "Beograd : Srpsko hemijsko društvo",
journal = "Knjiga izvoda / 8. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, Kruševac 30. maj - 1. jun 2018",
title = "Razvoj hromatografske metode za određivanje tragova veštačkih zaslađivača u vodi, Development of chromatografic method for trace determination of artificial
sweeteners in water",
pages = "168-167",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5944"
}

Gvozdić, E., Matić Bujagić, I., Grujić, S.,& Đurkić, T.. (2018). Razvoj hromatografske metode za određivanje tragova veštačkih zaslađivača u vodi. in Knjiga izvoda / 8. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, Kruševac 30. maj - 1. jun 2018
Beograd : Srpsko hemijsko društvo., 167-168.
https://hdl.handle.net/21.15107/rcub_technorep_5944

Gvozdić E, Matić Bujagić I, Grujić S, Đurkić T. Razvoj hromatografske metode za određivanje tragova veštačkih zaslađivača u vodi. in Knjiga izvoda / 8. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, Kruševac 30. maj - 1. jun 2018. 2018;:167-168.
https://hdl.handle.net/21.15107/rcub_technorep_5944 .

Gvozdić, Eleonora, Matić Bujagić, Ivana, Grujić, Svetlana, Đurkić, Tatjana, "Razvoj hromatografske metode za određivanje tragova veštačkih zaslađivača u vodi" in Knjiga izvoda / 8. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, Kruševac 30. maj - 1. jun 2018 (2018):167-168,
https://hdl.handle.net/21.15107/rcub_technorep_5944 .

TY  - CONF
AU  - Gvozdić, Eleonora
AU  - Matić Bujagić, Ivana
AU  - Tolić Stojadinović, Ljiljana
AU  - Grujić, Svetlana
AU  - Đurkić, Tatjana
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5946
AB  - Veštački zaslađivači se decenijama koriste kao aditivi u hrani, piću i farmaceutskim proizvodima. Savremena istraživanja su pokazala široku rasprostranjenost ovih supstanci u prirodnim i otpadnim vodama, zbog čega su svrstani u klasu emergentnih zagađujućih materija. U ovom radu je prikazana optimizacija metode pripreme uzoraka vode ekstrakcijom na čvrstoj fazi za određivanje tragova odabranih veštačkih zaslađivača. Ova metoda omogućava istovremeno izolovanje i koncentrovanje analita, ali i prečišćavanje ekstrakta uzorka. Prilikom razvoja metode izvršen je izbor optimalnog adsorbenta, zapremine i pH vrednosti uzorka vode, kao i rastvarača za eluiranje analita sa pakovanja kolone. Dobijeni ekstrakti su analizirani metodom tečne hromatografije–masene spektrometrije.
PB  - Novi Sad : Faculty of Technical Sciences, Department of Production Engineering
C3  - Proceedings / 12th Scientific Conference with International Participation ETIKUM 2018, Novi Sad, 06-08 December 2018
T1  - Priprema uzoraka vode za analizu veštačkih zaslađivača
EP  - 164
SP  - 161
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5946
ER  - 

@conference{
author = "Gvozdić, Eleonora and Matić Bujagić, Ivana and Tolić Stojadinović, Ljiljana and Grujić, Svetlana and Đurkić, Tatjana",
year = "2018",
abstract = "Veštački zaslađivači se decenijama koriste kao aditivi u hrani, piću i farmaceutskim proizvodima. Savremena istraživanja su pokazala široku rasprostranjenost ovih supstanci u prirodnim i otpadnim vodama, zbog čega su svrstani u klasu emergentnih zagađujućih materija. U ovom radu je prikazana optimizacija metode pripreme uzoraka vode ekstrakcijom na čvrstoj fazi za određivanje tragova odabranih veštačkih zaslađivača. Ova metoda omogućava istovremeno izolovanje i koncentrovanje analita, ali i prečišćavanje ekstrakta uzorka. Prilikom razvoja metode izvršen je izbor optimalnog adsorbenta, zapremine i pH vrednosti uzorka vode, kao i rastvarača za eluiranje analita sa pakovanja kolone. Dobijeni ekstrakti su analizirani metodom tečne hromatografije–masene spektrometrije.",
publisher = "Novi Sad : Faculty of Technical Sciences, Department of Production Engineering",
journal = "Proceedings / 12th Scientific Conference with International Participation ETIKUM 2018, Novi Sad, 06-08 December 2018",
title = "Priprema uzoraka vode za analizu veštačkih zaslađivača",
pages = "164-161",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5946"
}

Gvozdić, E., Matić Bujagić, I., Tolić Stojadinović, L., Grujić, S.,& Đurkić, T.. (2018). Priprema uzoraka vode za analizu veštačkih zaslađivača. in Proceedings / 12th Scientific Conference with International Participation ETIKUM 2018, Novi Sad, 06-08 December 2018
Novi Sad : Faculty of Technical Sciences, Department of Production Engineering., 161-164.
https://hdl.handle.net/21.15107/rcub_technorep_5946

Gvozdić E, Matić Bujagić I, Tolić Stojadinović L, Grujić S, Đurkić T. Priprema uzoraka vode za analizu veštačkih zaslađivača. in Proceedings / 12th Scientific Conference with International Participation ETIKUM 2018, Novi Sad, 06-08 December 2018. 2018;:161-164.
https://hdl.handle.net/21.15107/rcub_technorep_5946 .

Gvozdić, Eleonora, Matić Bujagić, Ivana, Tolić Stojadinović, Ljiljana, Grujić, Svetlana, Đurkić, Tatjana, "Priprema uzoraka vode za analizu veštačkih zaslađivača" in Proceedings / 12th Scientific Conference with International Participation ETIKUM 2018, Novi Sad, 06-08 December 2018 (2018):161-164,
https://hdl.handle.net/21.15107/rcub_technorep_5946 .

TY  - JOUR
AU  - Antanasijević, Davor
AU  - Matić-Bujagić, Ivana
AU  - Grujić, Svetlana
AU  - Laušević, Mila
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4020
AB  - In this paper, multivariate analysis of sterol concentrations detected in river sediment samples was performed. In order to remove co-dependence of values, concentrations of sterols were transformed using centered log-ratio (CLR) transformation. The main objective of the work was to point out the damaging effects of working in the wrong geometry on the principal component analysis (PCA) assessment of sterol pollution. In order to determine if the dimension lost have effect on the principal component analysis of sterols in sediments, we have performed the PCA using raw and log-ratio transformed sterol data. Additionally, two rounded zero replacement approaches, i.e. a simple-substitution method (DL/2, 0.55DL and DL/root 2) and multiplicative replacement strategy (0.65 DL), were compared in order to determine if the replacement values have an effect on PCA results and conclusions. Relevant differences were noted by comparing the results of the principal component analysis obtained with raw data and log-ratio transformed sterol data. Only the PC loadings obtained from the CLR PCA allowed the clear distinction between human-sourced pollution and biogenic sources of sterols, whereas in the case of PCA with raw data loadings were all grouped almost in a single quadrant. For the small proportion of rounded zeros (not more than 10%), two different replacement approaches did not have any effect on transformed PCA output. The results presented in this work have shown that the effect of "closure" in the sterol data can be easily observed from the PCA biplot, and that it obstructs the evaluation of human contribution to pollution of river sediments. Therefore, prior to the PCA, sterol concentrations must be CLR transformed in order to perform a reliable assessment of the sewage contamination.
PB  - Elsevier Science Bv, Amsterdam
T2  - Microchemical Journal
T1  - Effect of compositional data in the multivariate analysis of sterol concentrations in river sediments
EP  - 195
SP  - 188
VL  - 139
DO  - 10.1016/j.microc.2018.02.031
ER  - 

@article{
author = "Antanasijević, Davor and Matić-Bujagić, Ivana and Grujić, Svetlana and Laušević, Mila",
year = "2018",
abstract = "In this paper, multivariate analysis of sterol concentrations detected in river sediment samples was performed. In order to remove co-dependence of values, concentrations of sterols were transformed using centered log-ratio (CLR) transformation. The main objective of the work was to point out the damaging effects of working in the wrong geometry on the principal component analysis (PCA) assessment of sterol pollution. In order to determine if the dimension lost have effect on the principal component analysis of sterols in sediments, we have performed the PCA using raw and log-ratio transformed sterol data. Additionally, two rounded zero replacement approaches, i.e. a simple-substitution method (DL/2, 0.55DL and DL/root 2) and multiplicative replacement strategy (0.65 DL), were compared in order to determine if the replacement values have an effect on PCA results and conclusions. Relevant differences were noted by comparing the results of the principal component analysis obtained with raw data and log-ratio transformed sterol data. Only the PC loadings obtained from the CLR PCA allowed the clear distinction between human-sourced pollution and biogenic sources of sterols, whereas in the case of PCA with raw data loadings were all grouped almost in a single quadrant. For the small proportion of rounded zeros (not more than 10%), two different replacement approaches did not have any effect on transformed PCA output. The results presented in this work have shown that the effect of "closure" in the sterol data can be easily observed from the PCA biplot, and that it obstructs the evaluation of human contribution to pollution of river sediments. Therefore, prior to the PCA, sterol concentrations must be CLR transformed in order to perform a reliable assessment of the sewage contamination.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Microchemical Journal",
title = "Effect of compositional data in the multivariate analysis of sterol concentrations in river sediments",
pages = "195-188",
volume = "139",
doi = "10.1016/j.microc.2018.02.031"
}

Antanasijević, D., Matić-Bujagić, I., Grujić, S.,& Laušević, M.. (2018). Effect of compositional data in the multivariate analysis of sterol concentrations in river sediments. in Microchemical Journal
Elsevier Science Bv, Amsterdam., 139, 188-195.
https://doi.org/10.1016/j.microc.2018.02.031

Antanasijević D, Matić-Bujagić I, Grujić S, Laušević M. Effect of compositional data in the multivariate analysis of sterol concentrations in river sediments. in Microchemical Journal. 2018;139:188-195.
doi:10.1016/j.microc.2018.02.031 .

Antanasijević, Davor, Matić-Bujagić, Ivana, Grujić, Svetlana, Laušević, Mila, "Effect of compositional data in the multivariate analysis of sterol concentrations in river sediments" in Microchemical Journal, 139 (2018):188-195,
https://doi.org/10.1016/j.microc.2018.02.031 . .

TY  - CONF
AU  - Matić Bujagić, Ivana
AU  - Jauković, Zorica
AU  - Grujić, Svetlana
AU  - Gvozdić, Eleonora
AU  - Laušević, Mila
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5947
AB  - Komunalne otpadne vode i efluenti iz postrojenja za prečišćavanje otpadnih voda predstavljaju značajan izvor zagađujućih materija u vodenoj sredini. Studije su pokazale da se steroidna jedinjenja u postrojenjima za tretman ne uklanjaju u potpunosti, kao i da prisustvo steroida u vodi, čak i pri veoma niskim koncentracijama, može izazvati brojne neželjene efekte. U ovom radu analizirani su kompozitni uzorci otpadne vode, uzeti tokom pet dana sa dva ispusta komunalne vode u Novom Sadu. U uzorcima otpadne vode ispitivano je prisustvo 20 najčešće detektovanih steroidnih hormona i sterola optimizovanom metodom tečne hromatografije visokih performansi u sprezi sa tandem masenom spektrometrijom. Pored rastvornog oblika steroida, analizirana je i frakcija adsorbovana na suspendovanoj materiji.
PB  - Beograd : Srpsko hemijsko društvo
C3  - Knjiga izvoda / 8. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, Kruševac 30. maj - 1. jun 2018
T1  - Određivanje odabranih steroida u uzorcima komunalne otpadne vode
T1  - Determination of selected steroids in municipal wastewater samples
EP  - 170
SP  - 169
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5947
ER  - 

@conference{
author = "Matić Bujagić, Ivana and Jauković, Zorica and Grujić, Svetlana and Gvozdić, Eleonora and Laušević, Mila",
year = "2018",
abstract = "Komunalne otpadne vode i efluenti iz postrojenja za prečišćavanje otpadnih voda predstavljaju značajan izvor zagađujućih materija u vodenoj sredini. Studije su pokazale da se steroidna jedinjenja u postrojenjima za tretman ne uklanjaju u potpunosti, kao i da prisustvo steroida u vodi, čak i pri veoma niskim koncentracijama, može izazvati brojne neželjene efekte. U ovom radu analizirani su kompozitni uzorci otpadne vode, uzeti tokom pet dana sa dva ispusta komunalne vode u Novom Sadu. U uzorcima otpadne vode ispitivano je prisustvo 20 najčešće detektovanih steroidnih hormona i sterola optimizovanom metodom tečne hromatografije visokih performansi u sprezi sa tandem masenom spektrometrijom. Pored rastvornog oblika steroida, analizirana je i frakcija adsorbovana na suspendovanoj materiji.",
publisher = "Beograd : Srpsko hemijsko društvo",
journal = "Knjiga izvoda / 8. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, Kruševac 30. maj - 1. jun 2018",
title = "Određivanje odabranih steroida u uzorcima komunalne otpadne vode, Determination of selected steroids in municipal wastewater samples",
pages = "170-169",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5947"
}

Matić Bujagić, I., Jauković, Z., Grujić, S., Gvozdić, E.,& Laušević, M.. (2018). Određivanje odabranih steroida u uzorcima komunalne otpadne vode. in Knjiga izvoda / 8. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, Kruševac 30. maj - 1. jun 2018
Beograd : Srpsko hemijsko društvo., 169-170.
https://hdl.handle.net/21.15107/rcub_technorep_5947

Matić Bujagić I, Jauković Z, Grujić S, Gvozdić E, Laušević M. Određivanje odabranih steroida u uzorcima komunalne otpadne vode. in Knjiga izvoda / 8. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, Kruševac 30. maj - 1. jun 2018. 2018;:169-170.
https://hdl.handle.net/21.15107/rcub_technorep_5947 .

Matić Bujagić, Ivana, Jauković, Zorica, Grujić, Svetlana, Gvozdić, Eleonora, Laušević, Mila, "Određivanje odabranih steroida u uzorcima komunalne otpadne vode" in Knjiga izvoda / 8. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, Kruševac 30. maj - 1. jun 2018 (2018):169-170,
https://hdl.handle.net/21.15107/rcub_technorep_5947 .

TY  - CONF
AU  - Gvozdić, Eleonora
AU  - Matić Bujagić, Ivana
AU  - Tolić Stojadinović, Ljiljana
AU  - Grujić, Svetlana
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5945
AB  - After decades of using artificial sweeteners in the food and pharmaceutical industry, their ubiquitous presence in the environment has been determined 1,2. These substances are recognized as emerging pollutants due to limited data on their occurrence, environmental fate and ecotoxicity. Prior to analysis of artificial sweeteners at trace levels in water samples, it is necessary to isolate and concentrate analytes and clean-up the obtained extracts. In this paper, the optimization of the preparation method for the determination of saccharin, sucralose and neotame in water by solid-phase extraction (SPE) was performed. The extracts were analyzed by liquid chromatography–tandem mass spectrometry (LC–MS/MS). In the SPE optimization, the following parameters were tested: the sorbent type, the pH value and the volume of water sample and the elution solvent. The suitability of anion-exchange, polymeric, C18 and carbon sorbents for the extraction of selected sweeteners was assessed. The results showed that the highest recoveries were obtained using polymeric Oasis HLB cartridges, with copolymer poly(divinylbenzene-co-N-vinylpyrrolidone). Furthermore, it was determined that the pH value of water sample was crucial for extraction efficiency. For all three artificial sweeteners, the optimal pH value of the sample was 3. Finally, the sample volume of 100 ml ensured a high preconcentration factor without the sorbent breakthrough, and methanol was selected as the elution solvent.
PB  - Beograd : Srpsko hemijsko društvo
C3  - Kratki izvodi radova / Šesta konferencija mladih hemičara Srbije, Beograd, 27. oktobar 2018
T1  - Optimization of solid-phase extraction for analysis of artificial sweeteners in water
SP  - 33
UR  - https://hdl.handle.net/21.15107/rcub_technorep_5945
ER  - 

@conference{
author = "Gvozdić, Eleonora and Matić Bujagić, Ivana and Tolić Stojadinović, Ljiljana and Grujić, Svetlana",
year = "2018",
abstract = "After decades of using artificial sweeteners in the food and pharmaceutical industry, their ubiquitous presence in the environment has been determined 1,2. These substances are recognized as emerging pollutants due to limited data on their occurrence, environmental fate and ecotoxicity. Prior to analysis of artificial sweeteners at trace levels in water samples, it is necessary to isolate and concentrate analytes and clean-up the obtained extracts. In this paper, the optimization of the preparation method for the determination of saccharin, sucralose and neotame in water by solid-phase extraction (SPE) was performed. The extracts were analyzed by liquid chromatography–tandem mass spectrometry (LC–MS/MS). In the SPE optimization, the following parameters were tested: the sorbent type, the pH value and the volume of water sample and the elution solvent. The suitability of anion-exchange, polymeric, C18 and carbon sorbents for the extraction of selected sweeteners was assessed. The results showed that the highest recoveries were obtained using polymeric Oasis HLB cartridges, with copolymer poly(divinylbenzene-co-N-vinylpyrrolidone). Furthermore, it was determined that the pH value of water sample was crucial for extraction efficiency. For all three artificial sweeteners, the optimal pH value of the sample was 3. Finally, the sample volume of 100 ml ensured a high preconcentration factor without the sorbent breakthrough, and methanol was selected as the elution solvent.",
publisher = "Beograd : Srpsko hemijsko društvo",
journal = "Kratki izvodi radova / Šesta konferencija mladih hemičara Srbije, Beograd, 27. oktobar 2018",
title = "Optimization of solid-phase extraction for analysis of artificial sweeteners in water",
pages = "33",
url = "https://hdl.handle.net/21.15107/rcub_technorep_5945"
}

Gvozdić, E., Matić Bujagić, I., Tolić Stojadinović, L.,& Grujić, S.. (2018). Optimization of solid-phase extraction for analysis of artificial sweeteners in water. in Kratki izvodi radova / Šesta konferencija mladih hemičara Srbije, Beograd, 27. oktobar 2018
Beograd : Srpsko hemijsko društvo., 33.
https://hdl.handle.net/21.15107/rcub_technorep_5945

Gvozdić E, Matić Bujagić I, Tolić Stojadinović L, Grujić S. Optimization of solid-phase extraction for analysis of artificial sweeteners in water. in Kratki izvodi radova / Šesta konferencija mladih hemičara Srbije, Beograd, 27. oktobar 2018. 2018;:33.
https://hdl.handle.net/21.15107/rcub_technorep_5945 .

Gvozdić, Eleonora, Matić Bujagić, Ivana, Tolić Stojadinović, Ljiljana, Grujić, Svetlana, "Optimization of solid-phase extraction for analysis of artificial sweeteners in water" in Kratki izvodi radova / Šesta konferencija mladih hemičara Srbije, Beograd, 27. oktobar 2018 (2018):33,
https://hdl.handle.net/21.15107/rcub_technorep_5945 .